Measure TEER continuously—without pulling inserts out of the incubator. ECIS TEER products collect continuous, real-time TEER with fixed electrode positioning for consistent, repeatable measurements.
Common pain points with handheld or manual insert workflows:
Designed for long-term, reproducible TEER data capture:
Continuous TEER monitoring with ECIS transforms TEER from a static measurement into a real-time assay of barrier biology-revealing kinetics, transient effects, and reproducibility that single timepoint measurements simply cannot capture.
Continuous TEER measurement allows real-time tracking of barrier formation and disruption under incubated conditions, capturing transient or reversible changes that single timepoint measurements often miss. This approach reduces handling-induced variability and provides a more accurate, physiologically relevant view of barrier dynamics over time.
Monitor the formation, strengthening, and disruption of cell-cell junctions while cells remain under a more natural environment.
Monitor the variability of constantly changing cell barriers over time.
Electrodes don’t move while measurements are being taken, allowing for accurate, steady data.
ECIS® impedance measurements normally report resistance and capacitance as a series circuit. When the TEER value is relatively low, this series resistance at low AC frequency can be used as an effective measure of the barrier. However, when TEER values become much higher, as for many epithelial cells, some current will “sneak” capacitively through the cells, resulting in an incorrect low TEER measurement.
ECIS can take this into account and report the true TEER value. To do this, software converts the series RC circuit to a parallel one. This is not only a better representation of the cell (see diagram below), but also allows one to compensate for the sneak path and report the true barrier function.
© 2026 Applied BioPhysics, Inc.
185 Jordan
Road Troy, NY 12180 / Phone: 518-880-6860 / Toll Free: 866-301-ECIS (3247) / Fax: 518-880-6865
