Publications

Lipopolysaccharide-induced active telocyte exosomes alleviate lipopolysaccharide-induced vascular barrier disruption and acute lung injury via the activation of the miRNA-146a-5p/caspase-3 signaling pathway in endothelial cells.,  Huang, Xiaoqin,Zhang, Haoran  (2025).  Burns $ Trauma  13 (tkae074) :  doi:10.1093/burnst/tkae074 [Abstract]

Stabilizing milk-derived extracellular vesicles (mEVs) through lyophilization : a novel trehalose and tryptophan formulation for maintaining structure and Bioactivity during long-term storage.,  Dogan, Alan B,Marsh, Spencer R,Tschetter, Rachel J,Beard, Claire E,Amin, R,Jourdan, L Jane,Gourdie, Robert G  (2025).  Journal of Biological Engineering  19 (4) :  doi:10.1186/s13036-024-00470-z [Abstract]

Endothelial-Ercc1 DNA repair deficiency provokes blood-brain barrier dysfunction.,  Hansen, Cathrin E.,Vacondio, Davide,van der Molen, Lennart,Juttner, Annika A.,Ka Fung, Wing,Karsten, Manon,van het Hof, Bert,Fontijn, Ruud D.,Kooij, Gijs,Witte, Maarten E.,Roks, Anton J.M.,de Vries, Helga E.,Mulder, Inge,Wit, Nienke M De  (2025).  Cell Death and Disease  16 (1) :  1 doi:10.1038/s41419-024-07306-0 [Abstract]

Trying to Kill a Killer; Impressive Killing of Patient Derived Glioblastoma Cultures Using NK-92 Natural Killer Cells Reveals Both Sensitive and Highly Resistant Glioblastoma Cells.,  Yu, Jane,Kim, Hyeon Joo,Reinecke, Jordyn,Hucklesby, James,Read, Tennille,Anchan, Akshata,Angel, Catherine E.,Graham, Euan Scott  (2025).  Cells  14 (1) :  doi:10.3390/cells14010053 [Abstract]

Biomimetic astrocyte cell membrane-fused nanovesicles for protecting neurovascular units in hypoxic ischemic encephalopathy.,  Liu, Zihao,Xia, Qian,Wang, Chanyue,Xu, Jiacan,Tian, Kangqian,Wang, Zhihai,Li, Longji,Li, Yuchen,Shang, Hao,Liu, Qian,Xin, Tao  (2024).  Journal of Nanobiotechnology  (22) :  766 doi:10.1186/s12951-024-03053-8 [Abstract]

Impact of surface chemistry of upconversion nanoparticles on time-dependent cytotoxicity in non-cancerous epithelial cells.,  Märkl, Susanne,Przybilla, Frédéric,Rachel, Reinhard,Hirsch, Thomas,Keller, Max,Witzgall, Ralph,Mély, Yves,Wegener, Joachim  (2024).  Scientific Reports  14 (1) :  1-11 doi:10.1038/s41598-024-83406-3 [Abstract]

Succinate Regulates Endothelial Mitochondrial Function and Barrier Integrity.,  Atallah, Reham,Gindlhuber, Juergen,Platzer, Wolfgang,Rajesh, Rishi,Heinemann, Akos  (2024).  Antioxidants  13 (12) :  1-21 doi:10.3390/antiox13121579 [Abstract]

TNIK: A redox sensor in endothelial cell permeability.,  Joachim, Justin,Maselli, Davide,Petsolari, Emmanouela,Aman, Jurjan,Swiatlowska, Pamela,Killock, David,Chaudhry, Hiba,Zarban, Ali A.,Sarker, Mosharraf,Fraser, Paul,Cleary, Simon J.,Amison, Richard,Cuthbert, Isabelle,Yang, Yue,Meier, Magda,Fraternali, Franca,Brain, Susan D.,Shah, Ajay M.,Ivetic, Aleksandar  (2024).  Science advances  10 (51) :  eadk6583 doi:10.1126/sciadv.adk6583 [Abstract]

EPLIN, a prospective oncogenic molecule with contribution to growth, migration and drug resistance in pancreatic cancer.,  Zeng, Jianyuan,Wang, Cai,Ruge, Fiona,Ji, Edison Ke,Martin, Tracey A.,Sanders, Andrew J.,Jia, Shuqin,Hao, Chunyi,Jiang, Wen G.  (2024).  Scientific Reports  14 (1) :  1-21 doi:10.1038/s41598-024-81485-w [Abstract]

DRIM modulates Src activation and regulates angiogenic functions in vascular endothelial cells.,  Tong, Jia,Jiang, Wen G,Dong, Xuefei,Martin, Tracey A,Yang, Yiming,Dong, Bo  (2024).  Cell Biology International  (September) :  doi:10.1002/cbin.12265 [Abstract]

Epigenetic mechanisms mediate cytochrome P450 1A1 expression and lung endothelial injury caused by MRSA in vitro and in vivo.,  Ha, Alison W.,Meliton, Lucille N.,Chen, Weiguo,Wang, Lichun,Maienschein-Cline, Mark,Jacobson, Jeffrey R.,Letsiou, Eleftheria,Dudek, Steven M.  (2024).  FASEB Journal  38 (22) :  1-16 doi:10.1096/fj.202401812R [Abstract]

Impedance-based monitoring of titration and neutralization assays with VSV-G and SARS-CoV-2-spike pseudoviruses.,  Mildner, Anne Kathrin,Einhauser, Sebastian,Michaelis, Stefanie,Bieberstein, Klara Rogalla v.,Wagner, Ralf,Wegener, Joachim  (2024).  Applied Research  (August) :  1-12 doi:10.1002/appl.202400097 [Abstract]

Electrical impedance sensing in stem cell research: Insights, applications, and future directions.,  Moghtaderi, Hassan,Mohahammadi, Saeed,Sadeghian, Golfam,Choudhury, Mahua,Al-Harrasi, Ahmed,Rahman, Shaikh Mizanoor  (2024).  Progress in Biophysics and Molecular Biology  November 1 doi:10.1016/j.pbiomolbio.2024.11.004 [Abstract]

Electrical cell-substrate impedance sensing (ECIS) in lung biology and disease.,  Schaller, Lena,Hofmann, Katharina,Geiger, Fabienne,Dietrich, Alexander  (2024).  Applied Research  (April) :  1-10 doi:10.1002/appl.202400059 [Abstract]

Dual Inhibition of Phosphodiesterase 3 and 4 Enzymes by Ensifentrine Protects against MRSA-Induced Lung Endothelial and Epithelial Dysfunction.,  Al Matni, Mohammed Yaman,Meliton, Lucille,Dudek, Steven M.,Letsiou, Eleftheria  (2024).  Cells  13 (21) :  1750 doi:10.3390/cells13211750 [Abstract]

Cysteine Leukotriene Receptor Antagonist-Montelukast Effects on Diabetic Retinal Microvascular Endothelial Cells Curtail Autophagy.,  Awad, Ahmed M,Seetharaman, Amritha T M,Hossain, Mohammad Shahadat,Elshaer, Sally L,Abdelaziz, Rania R,Nader, Manar A,Gangaraju, Rajashekhar  (2024).  Investigative Ophthalmology and Visual Science  65 (13) :  15 doi:10.1167/iovs.65.13.15 [Abstract]

Metformin Improves the Function of Abdominal Aortic Aneurysm Patient- Derived Aortic Smooth Muscle Cells.,  Merrienboer, Tara A R Van,Rombouts, Karlijn B,Bogunovic, Natalija,Mieremet, Arnout,Meekel, Jorn P.,Balm, Ron,de Waard, Vivian,Yeung, Kak K.  (2024).  European Journal of Vascular & Endovascular Surgery  September doi:10.1016/j.ejvs.2024.09.022 [Abstract]

Biophysical Analysis of EGCG ’ s Protective Effects on Camptothecin-Induced Oxidative Stress in Bone-Like Cancer Cells Using Electric Cell-Substrate Impedance Sensing ( ECIS ).,  Nguyen, Ailinh,Joseph, Eugene,Clement, Peace,Alvarez, Gisela,Crogman, Horace T  (2024).  Biophysica  4 (4) :  530-544 doi:10.3390/biophysica4040035 [Abstract]

AAMP and MTSS1 Are Novel Negative Regulators of Endothelial Barrier Function Identified in a Proteomics Screen.,  Podieh, Fabienne,Overboom, Max C.,Knol, Jaco C.,Piersma, Sander R.,Goeij-de Haas, Richard,Pham, Thang V.,Jimenez, Connie R.,Hordijk, Peter L.  (2024).  Cells  13 (19) :  1-22 doi:10.3390/cells13191609 [Abstract]

Asymmetric dimethylarginine induces maladaptive function of the blood-brain barrier.,  Buzhdygan, Tetyana P.,Ramirez, Servio H.,Nenov, Miroslav N.  (2024).  Frontiers in Cell and Developmental Biology  12 (October) :  1-11 doi:10.3389/fcell.2024.1476386 [Abstract]

Rap1A Modulates Store-Operated Calcium Entry in the Lung Endothelium: A Novel Mechanism Controlling NFAT-Mediated Vascular Inflammation and Permeability.,  Kosuru, Ramoji,Romito, Olivier,Sharma, Guru Prasad,Ferraresso, Francesca,Ghadrdoost Nakhchi, Behshid,Yang, Kai,Mammoto, Tadanori,Mammoto, Akiko,Kastrup, Christian,Zhang, David,Goldspink, Paul,Trebak, Mohamed,Chrzanowska, Magdalena  (2024).  Arteriosclerosis, Thrombosis, and Vascular Biology  44 (11) :  2271-2287 doi:10.1161/ATVBAHA.124.321458 [Abstract]

TRPV4 Mediates Alveolar Epithelial Barrier Integrity and Induces ADAM10-Driven E-Cadherin Shedding.,  Schaller, Lena,Gudermann, Thomas,Dietrich, Alexander  (2024).  Cells  13 (20) :  1717 doi:10.3390/cells13201717 [Abstract]

Effect of Different Glucose Levels and Glycation on Meningioma Cell Migration and Invasion.,  Selke, Philipp,Strauss, Christian,Horstkorte, Rüdiger,Scheer, Maximilian  (2024).  International Journal of Molecular Sciences  25 (18) :  10075 doi:10.3390/ijms251810075 [Abstract]

The effect of nerve cells on the intestinal barrier function and the influence of human milk oligosaccharides (hMOs) on the intestinal neuro-epithelial crosstalk.,  Chen, Xiaochen,Gasaly, Naschla,Tang, Xin,Walvoort, Marthe T.C.,de Vos, Paul  (2024).  Current Research in Food Science  9 (July) :  100851 doi:10.1016/j.crfs.2024.100851 [Abstract]

Exploring the Immunomodulatory Potential of Human Milk: Aryl Hydrocarbon Receptor Activation and Its Impact on Neonatal Gut Health.,  Wieser, Naomi V.,Ghiboub, Mohammed,Verseijden, Caroline,van Goudoever, Johannes B.,Schoonderwoerd, Anne,de Meij, Tim G.J.,Niemarkt, Hendrik J.,Davids, Mark,Lefèvre, Antoine,Emond, Patrick,Derikx, Joep P.M.,Jonge, Wouter J.de,Sovran, Bruno  (2024).  Nutrients  16 (10) :  1531 doi:10.3390/nu16101531 [Abstract]

Growth behavior and mRNA expression profiling during growth of IPEC-J2 cells.,  Binder, A. Ronja D.,Mussack, Veronika,Kirchner, Benedikt,Pfaffl, Michael W.  (2024).  BMC Research Notes  17 (1) :  1-6 doi:10.1186/s13104-024-06812-w [Abstract]

Endothelial cell sphingosine 1-phosphate receptor 1 restrains VE-cadherin cleavage and attenuates experimental inflammatory arthritis.,  Burg, Nathalie,Malpass, Ryan,Alex, Linda,Tran, Miles,Englebrecht, Eric,Kuo, Andrew,Pannelini, Tania,Minett, Margaret,Athukorala, Kalana,Worgall, Tilla,Faust, Heather J.,Goodman, Susan,Mehta, Bella,Brenner, Michael,Vestweber, Dietmar,Wei, Kevin,Blobel, Carl,Hla, Timothy,Salmon, Jane E.  (2024).  JCI Insight  9 (11) :  1-18 doi:10.1172/jci.insight.171467 [Abstract]

The Role of TIM-1 and CD300a in Zika Virus Infection Investigated with Cell-Based Electrical Impedance.,  Oeyen, Merel,Heymann, Clément J.F.,Jacquemyn, Maarten,Daelemans, Dirk,Schols, Dominique  (2024).  Biosensors  14 (8) :  doi:10.3390/bios14080362 [Abstract]

Phylloquinone improves endothelial function, inhibits cellular senescence, and vascular inflammation.,  Kieronska-Rudek, Anna,Kij, Agnieszka,Bar, Anna,Kurpinska, Anna,Mohaissen, Tasnim,Grosicki, Marek,Stojak, Marta,Sternak, Magdalena,Buczek, Elżbieta,Proniewski, Bartosz,Kuś, Kamil,Suraj-Prazmowska, Joanna,Panek, Agnieszka,Pietrowska, Monika,Zapotoczny, Szczepan,Shanahan, Catherine M.,Szabo, Csaba,Chlopicki, Stefan  (2024).  GeroScience  46 (5) :  4909-4935 doi:10.1007/s11357-024-01225-w [Abstract]

Cell-substrate distance fluctuations of confluent cells enable fast and coherent collective migration.,  Jipp, Marcel,Wagner, Bente D,Egbringhoff, Lisa,Teichmann, Andreas,Rübeling, Angela,Nieschwitz, Paul,Honigmann, Alf,Chizhik, Alexey,Oswald, Tabea A,Janshoff, Andreas  (2024).  Cell Reports  43 (8) :  114553 doi:10.1016/j.celrep.2024.114553 [Abstract]

The significance of upper glycolytic components in regulating retinal pigment epithelial cellular behavior.,  Naghdi, Armaan,Oska, Nicole,Yumnamcha, Thangal,Eltanani, Shaimaa,Shawky, Mohamed,Me, Rao,Ibrahim, Ahmed S  (2024).  Scientific Reports  14 (18862) :  1-13 doi:10.1038/s41598-024-68343-5 [Abstract]

Serum from patients with cirrhosis undergoing liver transplantation induces permeability in human pulmonary microvascular endothelial cells ex vivo.,  Bokoch, Michael P.,Xu, Fengyun,Govindaraju, Krishna,Lloyd, Elliot,Tsutsui, Kyle,Kothari, Rishi P.,Adelmann, Dieter,Joffre, Jérémie,Hellman, Judith  (2024).  Frontiers in Medicine  11 (July) :  1-12 doi:10.3389/fmed.2024.1412891 [Abstract]

Cell – Electrode Models for Impedance Analysis of Epithelial and Endothelial Monolayers Cultured on Microelectrodes.,  Chiu, Wei-chih,Chen, Wei-ling,Lai, Yi-ting,Hung, Yu-han,Lo, Chun-Min  (2024).  Sensors  24 (13) :  1-14 doi:10.3390/s24134214 [Abstract]

Regulation of vascular endothelial integrity by mesenchymal stem cell extracellular vesicles after hemorrhagic shock and trauma.,  Barry, Mark,Trivedi, Alpa,Miyazawa, Byron,Vivona, Lindsay R,Shimmin, David,Pathipati, Praneeti,Keane, Callie,Cuschieri, Joseph,Pati, Shibani  (2024).  Journal of Translational Medicine  22 588 doi:10.1186/s12967-024-05406-1 [Abstract]

Cyanobacterial harmful bloom lipopolysaccharides: pro-inflammatory effects on epithelial and immune cells in vitro.,  Skočková, V.,Raptová, P.,Pospíchalová, K.,Sovadinová, I.,Sychrová, E.,Smutná, M.,Hilscherová, K.,Babica, P.,Šindlerová, L.  (2024).  Archives of Toxicology  98 (2) :  481-491 doi:10.1007/s00204-023-03644-8 [Abstract]

Off-targets of BRAF inhibitors disrupt endothelial signaling and vascular barrier function.,  Bromberger, Sophie,Zadorozhna, Yuliia,Ressler, Julia Maria,Holzner, Silvio,Nawrocki, Arkadiusz,Zila, Nina,Springer, Alexander,Larsen, Martin Røssel,Schossleitner, Klaudia  (2024).  Life Sci Alliance  7 (8) :  doi:10.26508/lsa.202402671 [Abstract]

Modulation of the Blood–Brain Barrier by Sigma-1R Activation.,  Brailoiu, Eugen,Barr, Jeffrey L,Wittorf, Hailey N,Inan, Saadet,Unterwald, Ellen M,Brailoiu, Gabriela Cristina  (2024).  International Journal of Molecular Sciences  25 (10) :  5147 doi:10.3390/ijms25105147 [Abstract]

Intrinsic endothelial hyper-responsiveness to inflammatory mediators drives acute episodes in models of Clarkson disease.,  Ablooglu, Ararat J.,Chen, Wei-Sheng,Xie, Zhihui,Desai, Abhishek,Paul, Subrata,Lack, Justin B.,Scott, Linda A.,Eisch, A. Robin,Dudek, Arkadiusz Z.,Parikh, Samir M.,Druey, Kirk M.  (2024).  Journal of Clinical Investigation  134 (10) :  e169137 doi:10.1172/jci169137 [Abstract]

Aging-regulated PNUTS maintains endothelial barrier function via SEMA3B suppression.,  Lozano-Vidal, Noelia,Stanicek, Laura,Bink, Diewertje I.,Juni, Rio P.,Hooglugt, Aukie,Kremer, Veerle,Phelp, Philippa,van Bergen, Anke,MacInnes, Alyson W.,Dimmeler, Stefanie,Boon, Reinier A.  (2024).  Communications Biology  7 (1) :  1-11 doi:10.1038/s42003-024-06230-5 [Abstract]

Chronic heart failure induces early defenestration of liver sinusoidal endothelial cells (LSECs) in mice.,  Wojnar-Lason, Kamila,Tyrankiewicz, Urszula,Kij, Agnieszka,Kurpinska, Anna,Kaczara, Patrycja,Kwiatkowski, Grzegorz,Wilkosz, Natalia,Giergiel, Magdalena,Stojak, Marta,Grosicki, Marek,Mohaissen, Tasnim,Jasztal, Agnieszka,Kurylowicz, Zuzanna,Szymonski, Marek,Czyzynska-Cichon, Izabela,Chlopicki, Stefan  (2024).  Acta Physiologica  240 (5) :  1-21 doi:10.1111/apha.14114 [Abstract]

Targeting IL-6 trans-signalling by sgp130Fc attenuates severity in SARS-CoV-2 -infected mice and reduces endotheliopathy.,  Rodríguez-Hernández, María Ángeles,Baena-Bustos, Mercedes,Carneros, David,Zurita-Palomo, Carola,Muñoz-Pinillos, Pablo,Millán, Jaime,Padillo, Francisco Javier,Smerdou, Cristian,von Kobbe, Cayetano,Rose-John, Stefan,Bustos, Matilde  (2024).  eBioMedicine  103 105132 doi:10.1016/j.ebiom.2024.105132 [Abstract]

MARCH family E3 ubiquitin ligases selectively target and degrade cadherin family proteins.,  Seo, Tadahiko,Lowery, Anthony M.,Xu, Haifang,Giang, William,Troyanovsky, Sergey M.,Vincent, Peter A.,Kowalczyk, Andrew P.  (2024).  PLoS One  19 (5) :  e0290485 doi:10.1371/journal.pone.0290485 [Abstract]

A novel “microbiota-host interaction model” to study the real-time effects of fermentation of non-digestible carbohydrate (NDCs) on gut barrier function.,  Chen, Xiaochen,Moreno, Luis Llanos,Tang, Xin,Gasaly, Naschla,Schols, Henk A.,de Vos, Paul  (2024).  Current Research in Food Science  8 (February) :  100736 doi:10.1016/j.crfs.2024.100736 [Abstract]

Cepharanthine maintains integrity of the blood-brain barrier (BBB) in stroke via the VEGF/VEGFR2/ZO-1 signaling pathway.,  Yang, Yunfang,Li, Changjiang,Yang, Sijin,Zhang, Zhuo,Bai, Xue,Tang, Hongmei,Huang, Jiang  (2024).  Aging  16 (7) :  5905-5915 doi:10.18632/aging.205678 [Abstract]

Control of endothelial cell function and arteriogenesis by MEG3:EZH2 epigenetic regulation of integrin expression.,  Dunn-Davies, Hywel,Dudnakova, Tatiana,Nogara, Antonella,Rodor, Julie,Thomas, Anita C.,Parish, Elisa,Gautier, Philippe,Meynert, Alison,Ulitsky, Igor,Madeddu, Paolo,Caporali, Andrea,Baker, Andrew,Tollervey, David,Mitić, Tijana  (2024).  Molecular Therapy Nucleic Acids  35 (2) :  1-22 doi:10.1016/j.omtn.2024.102173 [Abstract]

Inflammation-induced TRPV4 channels exacerbate blood–brain barrier dysfunction in multiple sclerosis.,  Hansen, Cathrin E.,Kamermans, Alwin,Mol, Kevin,Berve, Kristina,Rodriguez-Mogeda, Carla,Fung, Wing Ka,van het Hof, Bert,Fontijn, Ruud D.,van der Pol, Susanne M.A.,Michalick, Laura,Kuebler, Wolfgang M.,Kenkhuis, Boyd,van Roon-Mom, Willeke,Liedtke, Wolfgang,Engelhardt, Britta,Kooij, Gijs,Witte, Maarten E.,de Vries, Helga E.  (2024).  Journal of Neuroinflammation  21 (1) :  1-20 doi:10.1186/s12974-024-03069-9 [Abstract]

Modulation of the expression of connexins 37, 40, and 43 in endothelial cells in a culture.,  Zhuang, Wenqing,Mitrou, Nick G. A.,Kulak, Steve,Cupples, William A.,Braam, Branko  (2024).  Frontiers in Network Physiology  4 (March) :  doi:10.3389/fnetp.2024.1199198 [Abstract]

Azilsartan improves urinary albumin excretion in hypertension mice.,  Cao, Jun,Zhang, Dandan,Li, Wenfeng,Yuan, Wenjin,Luo, Gang,Xie, Shaofeng  (2024).  Aging  16 (5) :  4138-4148 doi:10.18632/aging.205271 [Abstract]

Designer high-density lipoprotein particles enhance endothelial barrier function and suppress inflammat.,  Lin, Yueh Chien,Swendeman, Steven,Moreira, Irina S.,Ghosh, Avishek,Kuo, Andrew,Rosário-Ferreira, Nícia,Guo, Shihui,Culbertson, Alan,Levesque, Michel V.,Cartier, Andreane,Seno, Takahiro,Schmaier, Alec,Galvani, Sylvain,Inoue, Asuka,Parikh, Samir M.,FitzGerald, Garret A.,Zurakowski, David,Liao, Maofu,Flaumenhaft, Robert,Gümüş, Zeynep H.,Hla, Timothy  (2024).  Science Signaling  17 (824) :  1-34 doi:10.1126/scisignal.adg9256 [Abstract]

Interleukin-22 Contributes to Blood-Brain Barrier Disruption via STAT3/VEGFA Activation in Escherichia coli Meningitis.,  Yang, Ruicheng,Chen, Jiaqi,Qu, Xinyi,Liu, Hulin,Wang, Xinyi,Tan, Chen,Chen, Huanchun,Wang, Xiangru  (2024).  ACS Infectious Diseases  10 (3) :  988-999 doi:10.1021/acsinfecdis.3c00668 [Abstract]

Vascular ATGL-dependent lipolysis and the activation of cPLA2–PGI2 pathway protect against postprandial endothelial dysfunction.,  Sternak, M.,Stojak, M.,Banasik, T.,Kij, A.,Bar, A.,Pacia, M. Z.,Wojnar-Lason, K.,Chorazy, N.,Mohaissen, T.,Marczyk, B.,Czyzynska-Cichon, I.,Berkimbayeva, Z.,Mika, A.,Chlopicki, S.  (2024).  Cellular and Molecular Life Sciences  81 (1) :  doi:10.1007/s00018-024-05167-6 [Abstract]

Monitoring Intestinal Organoid–Derived Monolayer Barrier Functions with Electric Cell–Substrate Impedance Sensing (ECIS).,  Ouahoud, Sarah,Giugliano, Francesca,Muncan, Vanesa  (2024).  Bio-Protocol  14 (5) :  e4947 doi:10.21769/bioprotoc.4947 [Abstract]

The deubiquitinase USP40 preserves endothelial integrity by targeting the heat shock protein HSP90β.,  Miao, Jiaxing,Li, Lian,Shaheen, Nargis,Wei, Jianxin,Jacko, Anastasia M.,Sundd, Prithu,Taleb, Sarah J.,Mallampalli, Rama K.,Zhao, Yutong,Zhao, Jing  (2024).  Experimental and Molecular Medicine  56 (2) :  395-407 doi:10.1038/s12276-024-01160-y [Abstract]

Electric cell-substrate impedance sensing in cancer research: An in-depth exploration of impedance sensing for profiling cancer cell behavior.,  Moghtaderi, Hassan,Sadeghian, Golfam,Abiri, Hamed,Khan, Faizullah,Rahman, Mizanur,Al-harrasi, Ahmed,Rahman, Shaikh Mizanoor  (2024).  Sensors and Actuators Reports  100188 doi:10.1016/j.snr.2024.100188 [Abstract]

HSP70 Is a Critical Regulator of HSP90 Inhibitor’s Effectiveness in Preventing HCl-Induced Chronic Lung Injury and Pulmonary Fibrosis.,  Colunga Biancatelli, R.M.L.,Solopov, P.A.,Day, T.,Gregory, B.,Osei-nkansah, M.,Dimitropoulou, C.,Catravas, J.D.  (2024).  International Journal of Molecular Sciences  25 (3) :  1920 doi:10.3390/ijms25031920 [Abstract]

Group A Streptococcus strains causing meningitis without distinct invasive phenotype.,  Marquardt, Laura,Andreoni, Federica,Boumasmoud, Mathilde,Schweizer, Tiziano A.,Heuberger, Dorothea M.,Parietti, Elena,Hertegonne, Sanne,Epprecht, Jana,Mattle, Dario,Raez, Anna K.,Marques-Maggio, Ewerton,Schuepbach, Reto A.,Hasse, Barbara,Mairpady-Shambat, Srikanth,Brugger, Silvio D.,Zinkernagel, Annelies S.  (2024).  MicrobiologyOpen  13 (1) :  1-10 doi:10.1002/mbo3.1394 [Abstract]

Cortactin is in a complex with VE-cadherin and is required for endothelial adherens junction stability through Rap1/Rac1 activation.,  Moztarzadeh, Sina,Sepic, Sara,Hamad, Ibrahim,Waschke, Jens,Radeva, Mariya Y.,García-Ponce, Alexander  (2024).  Scientific Reports  14 (1) :  1-18 doi:10.1038/s41598-024-51269-3 [Abstract]

Investigation of the functional impact of CHED- and FECD4-associated SLC4A11 mutations in human corneal endothelial cells.,  Id, Doug D Chung,Chen, Angela C,Choo, Charlene H,Id, Wenlin Zhang,Williams, Dominic,Griffis, Christopher G,Bonezzi, Paul,Jatavallabhula, Kavya,Sampath, Alapakkam P,Id, Anthony J Aldave  (2024).  PLOS ONE  19 (1) :  e0296928 doi:10.1371/journal.pone.0296928 [Abstract]

PVT1 promotes proliferation and macrophage immunosuppressive polarization through STAT1 and CX3CL1 regulation in glioblastoma multiforme.,  Huang, Lijie,Wang, Zheng,Liao, Chihyi,Zhao, Zheng,Gao, Hua,Huang, Ruoyu,Chen, Jing,Wu, Fan,Zeng, Fan,Zhang, Ying,Jiang, Tao,Hu, Huimin  (2024).  CNS Neuroscience and Therapeutics  30 (1) :  1-15 doi:10.1111/cns.14566 [Abstract]

The Protective Role of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Protein Sigma-1 Receptor in Regulating Endothelial Inflammation and Permeability Associated with Acute Lung Injury.,  Mahamed, Zahra,Shadab, Mohammad,Najar, Rauf Ahmad,Millar, Michelle Warren,Bal, Jashandeep,Pressley, Traci,Fazal, Fabeha  (2024).  Cells  13 (1) :  5 doi:10.3390/cells13010005 [Abstract]

Synergistic effects of nanosecond pulsed plasma and electric field on inactivation of pancreatic cancer cells in vitro.,  Oshin, Edwin A.,Minhas, Zobia,Colunga Biancatelli, Ruben M. L.,Catravas, John D.,Heller, Richard,Guo, Siqi,Jiang, Chunqi  (2024).  Scientific Reports  14 (885) :  1-1 doi:10.1038/s41598-024-51298-y [Abstract]

Transmembrane Protein CMTM6 Alleviates Ocular Inflammatory Response and Improves Corneal Epithelial Barrier Function in Experimental Dry Eye.,  Zhou, Yifan,Ma, Baikai,Liu, Qiyao,Duan, Hongyu,Huo, Yangbo,Zhao, Lu,Chen, Jiawei,Han, Wenling,Qi, Hong  (2024).  Invest Opthalmology Visual Science  65 (1) :  4 doi:10.1167/iovs.65.1.4 [Abstract]

Metastatic Lymph Node 64 (MLN64) Expression in Gastric Cancer: The Clinical and Molecular Implications in Drug Resistance..,  Li, Amber Xinyu,Zeng, Jimmy Jianyuan,Khan, Elyas,Dou, Q Ping,Zhuang, Xinguo,Ji, Edison Ke,Ruge, Fiona,Martin, Tracey A,Jia, Shuqin,Jiang, Wen G  (2024).  Cancer genomics & proteomics  21 (1) :  30-40 doi:10.21873/cgp.20427 [Abstract]

Dually Modified Cellulose as a Non-Viral Vector for the Delivery and Uptake of HDAC3 siRNA.,  Hülsmann, Juliana,Lindemann, Henry,Wegener, Jamila,Kühne, Marie,Godmann, Maren,Koschella, Andreas,Coldewey, Sina M,Heinze, Thomas,Heinzel, Thorsten  (2023).  Pharmaceutics  15 (12) :  1-22 doi:10.3390/pharmaceutics15122659 [Abstract]

Activation of mTOR signaling in adult lung microvascular progenitor cells accelerates lung aging.,  Mason, Emma C.,Menon, Swapna,Schneider, Benjamin R.,Gaskill, Christa F.,Dawson, Maggie M.,Moore, Camille M.,Armstrong, Laura Craig,Cho, Okyong J.,Richmond, Bradley W.,Kropski, Jonathan A.,West, James D.,Geraghty, Patrick,Gomperts, Brigitte N.,Ess, Kevin C.,Gally, Fabienne,Majka, Susan M.  (2023).  Journal of Clinical Investigation  133 (24) :  e171430 doi:10.1172/jci171430 [Abstract]

A Novel Combination Therapy Tβ4/VIP Protects against Hyperglycemia-Induced Changes in Human Corneal Epithelial Cells.,  Ebrahim, Abdul Shukkur,Carion, Thomas W.,Ebrahim, Thanzeela,Win, Jeff,Kani, Hussein,Wang, Yuxin,Stambersky, Ashten,Ibrahim, Ahmed S.,Sosne, Gabriel,Berger, Elizabeth A.  (2023).  Biosensors  13 (11) :  974 doi:10.3390/bios13110974 [Abstract]

Pharmacological Modulation of β-Catenin Preserves Endothelial Barrier Integrity and Mitigates Retinal Vascular Permeability and Inflammation.,  Rudraraju, Madhuri,Shan, Shengshuai,Liu, Fang,Tyler, Jennifer,Caldwell, Ruth B.,Somanath, Payaningal R.,Narayanan, S. Priya  (2023).  Journal of Clinical Medicine  12 (22) :  7145 doi:10.3390/jcm12227145 [Abstract]

Sphingosine-1-Phosphate Receptor 3 Induces Endothelial Barrier Loss via ADAM10-Mediated Vascular Endothelial-Cadherin Cleavage.,  Wu, Jialin,Liang, Ying,Fu, Panfeng,Feng, Anlin,Lu, Qing,Unwalla, Hoshang J.,Marciano, David P.,Black, Stephen M.,Wang, Ting  (2023).  International Journal of Molecular Sciences  24 (22) :  16083 doi:10.3390/ijms242216083 [Abstract]

Cationic LNP-formulated mRNA expressing Tie2-agonist in the lung endothelium prevents pulmonary vascular leakage.,  Radloff, Katrin,Gutbier, Birgitt,Dunne, Charlotte Maeve,Moradian, Hanieh,Schwestka, Marko,Gossen, Manfred,Ahrens, Katharina,Kneller, Laura,Wang, Yadong,Moga, Akanksha,Gkionis, Leonidas,Keil, Oliver,Fehring, Volker,Tondera, Daniel,Giese, Klaus,Santel, Ansgar,Kaufmann, Jörg,Witzenrath, Martin  (2023).  Molecular Therapy Nucleic Acids  34 (December) :  102068 doi:10.1016/j.omtn.2023.102068 [Abstract]

Upper glycolytic components contribute differently in controlling retinal vascular endothelial cellular behavior : Implications for endothelial-related retinal diseases.,  Oska, Nicole,Eltanani, Shaimaa,Shawky, Mohamed,Naghdi, Armaan,Gregory, Andrew,Yumnamcha, Thangal,Id, Ahmed S Ibrahim  (2023).  PLOS ONE  18 (11) :  1-20 doi:10.1371/journal.pone.0294909 [Abstract]

Phenotype plasticity and altered sensitivity to chemotherapeutic agents in aggressive prostate cancer cells.,  Paxson, Allan I,Chang, Loren H,Gard, Jaime M C,Harryman, William L,Nelson, Colin S,Salmon, Stella B,Marr, Kendra D,Wachsmuth, Leah M,Ramanathan, Anita,Ran, Jing,Kapoor, Abhijeet,Marugan, Juan J,Henderson, Mark J,Sanchez, Tino W,Cress, Anne E  (2023).  Frontiers in Cell and Developmental Biology  11 (November) :  1-10 doi:10.3389/fcell.2023.1285372 [Abstract]

A ligand-independent Tie2-activating antibody reduces vascular leakage in models of Clarkson disease.,  Ablooglu, Ararat J,Desai, Abhishek,Yoo, Jin-san,Park, Cheon Ho,Lee, Eun-ah,Kim, Bu Yeon,Park, Hyunsun,Lee, Young Ae,Shim, Sang Ryeol,Lee, Weon Sup,Druey, Kirk M  (2023).  Science Advances  9 (46) :  1394 doi:10.1126/sciadv.adi1394 [Abstract]

LPA2 Alleviates Septic Acute Lung Injury via Protective Endothelial Barrier Function Through Activation of PLC-PKC-FAK.,  Bai, Ruifeng,Pei, Jianqiu,Pei, Shengqiang,Cong, Xiangfeng,Chun, Jerold,Wang, Fang,Chen, Xi  (2023).  Journal of Inflammation Research  16 (November) :  5095-5109 doi:10.2147%2FJIR.S419578 [Abstract]

Multi-Omics Analysis of Circulating Exosomes in Adherent Long-Term Treated OSA Patients.,  Khalyfa, Abdelnaby,Marin, Jose M,Sanz-rubio, David,Lyu, Zhen,Joshi, Trupti,Gozal, David  (2023).  International Journal of Molecular Sciences  24 (22) :  [Abstract]

Human organoids are superior to cell culture models for intestinal barrier research.,  Kollmann, Catherine,Buerkert, Hannah,Meir, Michael,Richter, Konstantin,Kretzschmar, Kai,Flemming, Sven,Kelm, Matthias,Germer, Christoph-Thomas,Otto, Christoph,Burkard, Natalie,Schlegel, Nicolas  (2023).  Frontiers in Cell and Developmental Biology  11 (October) :  1223032 doi:10.3389/fcell.2023.1223032 [Abstract]

Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation dis- rupts endothelial adherens junctions.,  Tiruppathi, Chinnaswamy,Wang, Dong-mei,Ansari, Mohammad Owais,Bano, Shabana,Tsukasaki, Yoshikazu,Mukhopadhyay, Amitabha,Joshi, Jagdish C,Loch, Christian,Niessen, Hans W M,Malik, Asrar B  (2023).  Nature Communications  14 (6582) :  doi:10.1038/s41467-023-42225-2 [Abstract]

UCHL1 Regulates Radiation Lung Injury via Sphingosine Kinase-1.,  Epshtein, Yulia,Mathew, Biji,Chen, Weiguo,Jacobson, Jeffrey R  (2023).  Cells  12 (19) :  2405 doi:10.3390/cells12192405 [Abstract]

Endothelial barrier dysfunction in systemic inflammation is mediated by soluble VE-cadherin interfering VE-PTP signaling.,  Knop, Juna-lisa,Burkard, Natalie,Danesh, Mahshid,Kintrup, Sebastian,Dandekar, Thomas,Srivastava, Mugdha,Springer, Rebecca,Hiermaier, Matthias,Wagner, Nana-Maria,Waschke, Jens,Flemming, Sven,Schlegel, Nicolas  (2023).  iScience  26 (10) :  108049 doi:10.1016/j.isci.2023.108049 [Abstract]

MicroRNA-1 protects the endothelium in acute lung injury.,  Korde, Asawari,Haslip, Maria,Pednekar, Prachi,Khan, Alamzeb,Chioccioli, Maurizio,Mehta, Sameet,Lopez-Giraldez, Francesc,Bermejo, Santos,Rojas, Mauricio,Dela Cruz, Charles,Matthay, Michael A.,Pober, Jordan S.,Pierce, Richard W.,Takyar, Shervin S.  (2023).  JCI insight  8 (18) :  1-20 doi:10.1172/jci.insight.164816 [Abstract]

Myeloperoxidase enhances the migration and invasion of human choriocarcinoma JEG-3 cells.,  Mihalic, Z.N.,Kloimböck, T.,Cosic-Mujkanovic, N.,Valadez-Cosmes, P.,Maitz, K.,Kindler, O.,Wadsack, C.,Heinemann, A.,Marsche, G.,Gauster, M.,Pollheimer, J.,Kargl, J.  (2023).  Redox Biology  67 (April) :  102885 doi:10.1016/j.redox.2023.102885 [Abstract]

The effect of circulating iron on barrier integrity of primary human endothelial cells.,  Madsen, M C,Podieh, F,Overboom, M C,Thijs, A,Heijer, M Den,Hordijk, P L  (2023).  Scientific Reports  13 1-11 doi:10.1038/s41598-023-44122-6 [Abstract]

Disheveled-1 Interacts with Claudin-5 and Contributes to Norrin-Induced Endothelial Barrier Restoration.,  Diaz-Coranguez, Monica,Gonzalez-Gonzalez, Laura,Wang, Amy,Liu, Xuwen,Antonetti, David A.  (2023).  Cells  12 (19) :  doi:10.3390/cells12192402 [Abstract]

Uptake and effects of polystyrene nanoplastics in comparison to non-plastic silica nanoparticles on small intestine cells (IPEC-J2).,  Binder, Anna Ronja Dorothea,Mussack, Veronika,Kirchner, Benedikt,Pfaffl, Michael W.  (2023).  Ecotoxicology and Environmental Safety  262 (June) :  115147 doi:10.1016/j.ecoenv.2023.115147 [Abstract]

Higher gestational weight gain delays wound healing and reduces expression of long non-coding RNA KLRK1-AS1 in neonatal endothelial progenitor cells.,  Weiss, Elisa,Schrüfer, Anna,Tocantins, Carolina,Diniz, Mariana Simoes,Novakovic, Boris,van Bergen, Anke S.,Kulovic-Sissawo, Azra,Saffery, Richard,Boon, Reinier A.,Hiden, Ursula  (2023).  Journal of Physiology  601 (17) :  3961-3974 doi:10.1113/JP284871 [Abstract]

Influenza H7N9 virus disrupts the monolayer human brain microvascular endothelial cells barrier in vitro.,  Lei, Yuxuan,Sun, Ying,Wu, Weihua,Liu, Hui,Wang, Xin,Shu, Yuelong,Fang, Shisong  (2023).  Virology Journal  20 219 doi:10.1186/s12985-023-02163-3 [Abstract]

Elevated PLAUR is observed in the airway epithelium of asthma patients and blocking improves barrier integrity.,  Portelli, Michael A,Bhaker, Sangita,Pang, Vincent,Bates, David O,Johnson, Simon R,Mazar, Andrew P,Shaw, Dominick,Brightling, Christopher,Sayers, Ian  (2023).  Clinical and Translational Allergy  13 (10) :  e12293 doi:10.1002/clt2.12293 [Abstract]

Non-Lethal Doses of RSL3 Impair Microvascular Endothelial Barrier through Degradation of Sphingosie-1-Phosphate Receptor 1 and Cytoskeletal Arrangement in A Ferroptosis-Independent Manner.,  Baoyinna, Boina,Miao, Jiaxing,Oliver, Patrick J.,Ye, Qinmao,Shaheen, Nargis,Kalin, Timothy,He, Jinshan,Parinandi, Narasimham L.,Zhao, Yutong,Zhao, Jing  (2023).  Biomedicines  11 (9) :  2451 doi:10.3390/biomedicines11092451 [Abstract]

The contribution of reticular basement membrane proteins to basal airway epithelial attachment, spreading and barrier formation: implications for airway remodeling in asthma.,  Hsieh, Aileen,Yang, Chen Xi,Al-Fouadi, May,Nwozor, Kingsley Okechukwu,Osei, Emmanuel Twumasi,Hackett, Tillie-Louise  (2023).  Frontiers in Medicine  10 (September) :  1-10 doi:10.3389/fmed.2023.1214130 [Abstract]

The Multi-Kinase Inhibitor RepSox Enforces Barrier Function in the Face of Both VEGF and Cytokines.,  Lietuvninkas, Lina,Baccouche, Basma,Kazlauskas, Andrius  (2023).  Biomedicines  11 (9) :  2431 doi:10.3390/biomedicines11092431 [Abstract]

Metabolism of Acetaminophen by Enteric Epithelial Cells Mitigates Hepatocellular Toxicity In Vitro.,  Morgan, Katie,Morley, Steven D.,Raja, Arslan K.,Vandeputte, Martin,Samuel, Kay,Waterfall, Martin,Homer, Natalie Z.M.,Hayes, Peter C.,Fallowfield, Jonathan A.,Plevris, John N.  (2023).  Journal of Clinical Medicine  12 (12) :  3995 doi:10.3390/jcm12123995 [Abstract]

Sodium Butyrate as Key Regulator of Mitochondrial Function and Barrier Integrity of Human Glomerular Endothelial Cells.,  Nicese, Maria Novella,Bijkerk, Roel,Zonneveld, Anton Jan Van,Berg, Bernard M Van Den,Rotmans, Joris I  (2023).  International Journal of Molecular Sciences  24 (17) :  13090 doi:10.3390/ijms241713090 [Abstract]

Particulate matter increases connexin 43 expression and function, exacerbating endothelial barrier disruption.,  Zhang, Jun,Wu, Xiaomin,Liang, Ying,Kelly, Gabriel,Burt, Janis M,Zhang, Liming,Wang, Ting  (2023).  American Journal of Translational Research  15 (8) :  5099-5109 doi:PMC10492082 [Abstract]

Direct endothelial ENaC activation mitigates vasculopathy induced by SARS-CoV2 spike protein.,  Romero, Maritza J,Yue, Qian,Singla, Bhupesh,Hamacher, Jürg,Sridhar, Supriya,Moseley, Auriel S,Song, Chang,Mraheil, Mobarak A,Fischer, Bernhard,Zeitlinger, Markus,Chakraborty, Trinad,Fulton, David,Gan, Lin,Annex, Brian H,Csanyi, Gabor,Eaton, Douglas C,Lucas, Rudolf  (2023).  Frontiers in Immunology  2 (August) :  1-13 doi:10.3389/fimmu.2023.1241448 [Abstract]

Aging-Related Accumulation of Truncated Oxidized Phospholipids Augments Infectious Lung Injury and Endothelial Dysfunction via Cluster of Differentiation 36-Dependent Mechanism.,  Ke, Yunbo,Karki, Pratap,Li, Yue,Promnares, Kamoltip,Zhang, Chen-ou,Eggerman, Thomas L,Bocharov, Alexander V,Birukova, Anna A,Birukov, Konstantin G  (2023).  Cells  12 (15) :  1937 doi:10.3390/cells12151937 [Abstract]

Opto-RhoGEFs: an optimized optogenetic toolbox to reversibly control Rho GTPase activity on a global to subcellular scale, enabling precise control over vascular endothelial barrier strength.,  Mahlandt, Eike K.,Martínez, Sebastián Palacios,Arts, Janine J.G.,Tol, Simon,Buul, Jaap D. van,Goedhart, Joachim  (2023).  eLife  12 (RP84364.) :  doi:10.7554/eLife.84364 [Abstract]

VEGF Induces Expression of Genes That Either Promote or Limit Relaxation of the Retinal Endothelial Barrier.,  McCann, Maximilian,Li, Yueru,Baccouche, Basma,Kazlauskas, Andrius  (2023).  International Journal of Molecular Sciences  24 (7) :  doi:10.3390/ijms24076402 [Abstract]

Integrated Analysis of Tracheobronchial Fluid from Before and After Cardiopulmonary Bypass Reveals Activation of the Integrated Stress Response and Altered Pulmonary Microvascular Permeability.,  Habet, Victoria,Li, Ningshan,Qi, Ji,Peng, Gang,Charkoftaki, Georgia,Vasiliou, Vasilis,Sharma, Lokesh,Pober, Jordan S.,Cruz, Charles Dela,Yan, Xiting,Pierce, Richard W.  (2023).  Yale Journal of Biology and Medicine  96 (1) :  23-42 doi:10.59249/KFYZ8002 [Abstract]

CHIR99021 Maintenance of the Cell Stemness by Regulating Cellular Iron Metabolism.,  Han, Yingying,He, Yong,Jin, Xiaofang,Xie, Jiayi,Yu, Peng,Gao, Guofen,Chang, Shiyang,Zhang, Jianhua,Chang, Yan Zhong  (2023).  Antioxidants  12 (2) :  doi:10.3390/antiox12020377 [Abstract]

Differential role for rapid proteostasis in Rho GTPase-mediated control of quiescent endothelial integrity.,  Podieh, Fabienne,Wensveen, Roos,Overboom, Max C.,Abbas, Lotte,Majolée, Jisca,Hordijk, Peter L.  (2023).  Journal of Biological Chemistry  299 (4) :  104593 doi:10.1016/j.jbc.2023.104593 [Abstract]

Combining Electrostimulation with Impedance Sensing to Promote and Track Osteogenesis within a Titanium Implant.,  Engel, Nadja,Dau, Michael,Engel, Vivien,Franz, Denise,Klemmstein, Fabian,Thanisch, Christiane,Kolb, Jürgen F.,Frank, Marcus,Springer, Armin,Köhling, Rüdiger,Bader, Rainer,Frerich, Bernhard,Wiesmann, Nadine,Heimes, Diana,Kämmerer, Peer W.  (2023).  Biomedicines  11 (3) :  doi:10.3390/biomedicines11030697 [Abstract]

Impact of blood factors on endothelial cell metabolism and function in two diverse heart failure models.,  Song, Young,Leem, Joseph,Dhanani, Mehul,McKirnan, M. Dan,Ichikawa, Yasuhiro,Braza, Julie,Harrington, Elizabeth O.,Hammond, H. Kirk,Roth, David M.,Patel, Hemal H.  (2023).  PLoS ONE  18 (2 February) :  1-17 doi:10.1371/journal.pone.0281550 [Abstract]

7-Ketocholesterol Promotes Retinal Pigment Epithelium Senescence and Fibrosis of Choroidal Neovascularization via.,  Wang, Haibo,Ramshekar, Aniket,Cung, Thaonhi,Wallace-carrete, Chris,Zaugg, Chandler,Nguyen, Jasmine,Stoddard, Gregory J,Hartnett, M Elizabeth  (2023).  International Journal of Molecular Sciences  24 (12) :  10276 doi:10.3390/ijms241210276 [Abstract]

Marked elevations in lung and plasma ceramide in COVID-19 linked to microvascular injury.,  Petrache, Irina,Pujadas, Elisabet,Ganju, Aditya,Serban, Karina A.,Borowiec, Alexander,Babbs, Beatrice,Bronova, Irina A.,Egersdorf, Nicholas,Hume, Patrick S.,Goel, Khushboo,Janssen, William J.,Berdyshev, Evgeny V.,Cordon-Cardo, Carlos,Kolesnick, Richard  (2023).  JCI Insight  8 (10) :  1-9 doi:10.1172/jci.insight.156104 [Abstract]

Perillyl alcohol modulates activation , permeability and integrity of human brain endothelial cells induced by Plasmodium falciparum.,  Marin, Adriana A,Juillard, Annette,Katzin, Alejandro M,Carvalho, Leonardo J M,Grau, Georges E R  (2023).  Memorias Do Instituto Oswaldo Cruz  118 (18) :  1-9 doi:10.1590/0074-02760230033 [Abstract]

Metformin alleviates lung-endothelial hyperpermeability by regulating cofilin-1/PP2AC pathway.,  Siddiqui, M Rizwan,Reddy, Narsa M,Faridi, Hafeez M,Shahid, Mohd,Shanley, Thomas P  (2023).  Frontiers in Pharmacology  14 (June) :  1-10 doi:10.3389/fphar.2023.1211460 [Abstract]

SOX17 Enhancer Variants Disrupt Transcription Factor Binding And Enhancer Inactivity Drives Pulmonary Hypertension.,  Walters, Rachel,Vasilaki, Eleni,Aman, Jurjan,Chen, Chien Nien,Wu, Yukyee,Liang, Olin D.,Ashek, Ali,Dubois, Olivier,Zhao, Lin,Sabrin, Farah,Cebola, Inês,Ferrer, Jorge,Morrell, Nicholas W.,Klinger, James R.,Wilkins, Martin R.,Zhao, Lan,Rhodes, Christopher J.  (2023).  Circulation  147 (21) :  1606-1621 doi:10.1161/CIRCULATIONAHA.122.061940 [Abstract]

Effects of sevoflurane on lung epithelial permeability in experimental models of acute respiratory distress syndrome.,  Zhai, Ruoyang,Lenga Ma Bonda, Woodys,Leclaire, Charlotte,Saint-Béat, Cécile,Theilliere, Camille,Belville, Corinne,Coupet, Randy,Blondonnet, Raiko,Bouvier, Damien,Blanchon, Loic,Sapin, Vincent,Jabaudon, Matthieu  (2023).  Journal of Translational Medicine  21 (397) :  1-16 doi:10.1186/s12967-023-04253-w [Abstract]

Basement membrane product , endostatin , as a link between inflammation , coagulation and vascular permeability in COVID- 19 and non-COVID-19 acute respiratory distress syndrome.,  Jandl, Katharina,Berg, Johannes Lorenz,Birnhuber, Anna,Fliesser, Elisabeth,Borek, Izabela,Seeliger, Benjamin,David, Sascha,Schmidt, Julius J,Gorkiewicz, Gregor,Zacharias, Martin,Welte, Tobias,Olschewski, Horst,Heinemann, Akos,Wygrecka, Malgorzata,Kwapiszewska, Grazyna  (2023).  Frontiers in Immunology  14 (May) :  1-11 doi:10.3389/fimmu.2023.1188079 [Abstract]

Lung infection by P . aeruginosa induces neuroinflammation and blood-brain barrier dysfunction in mice.,  Villalba, Nuria,Ma, Yonggang,Gahan, Sarah A,Joly-amado, Aurelie,Spence, Sam,Yang, Xiaoyuan,Nash, Kevin,Yuan, Sarah Y  (2023).  Research Square  20 (127) :  1-18 doi:10.1186/s12974-023-02817-7 [Abstract]

Activin A Limits VEGF-Induced Permeability via VE-PTP.,  Baccouche, Basma,Lietuvninkas, Lina,Kazlauskas, Andrius  (2023).  International Journal of Molecular Sciences  24 (10) :  8698 doi:10.3390/ijms24108698 [Abstract]

Beyond Pattern Recognition: TLR2 Promotes Chemotaxis, Cell Adhesion, and Migration in THP-1 Cells.,  Colleselli, Katrin,Ebeyer-masotta, Marie,Neuditschko, Benjamin,Stierschneider, Anna,Pollhammer, Christopher,Potocnjak, Mia,Hundsberger, Harald,Herzog, Franz,Wiesner, Christoph  (2023).  Cells  12 (10) :  1425 doi:10.3390/cells12101425 [Abstract]

Expression of ALCAM in Clinical Colon Cancer and Relationship With Patients' Treatment Responses..,  Fang, Ziqian,Zeng, Jimmy Jianyuan,Yang, Yiming,Ruge, Fiona,Lane, Jane,Hargest, Rachel,Jiang, Wen G  (2023).  In vivo (Athens, Greece)  37 (3) :  1117-1128 doi:10.21873/invivo.13187 [Abstract]

Bone Morphogenetic Protein-4 Impairs Retinal Endothelial Cell Barrier, a Potential Role in Diabetic Retinopathy.,  Darwish, Noureldien H E,Hussein, Khaled A,Elmasry, Khaled,Ibrahim, Ahmed S,Humble, Julia,Moustafa, Mohamed,Awadalla, Fatma,Al-shabrawey, Mohamed  (2023).  Cells  12 (9) :  1279 doi:10.3390/cells12091279 [Abstract]

Heterozygosity for ADP-ribosylation factor 6 suppresses the burden and severity of atherosclerosis.,  Gogulamudi, Venkateswara R,Islam, Md Torikul,Durrant, Jessica R,Adeyemo, Adelola O,Trott, Daniel W,Hyuhn, Mi Ho,Zhu, Weiquan,Donato, Anthony J,Walker, Ashley E,Lesniewski, Lisa A  (2023).  PLOS ONE  18 (5) :  1-17 doi:10.1371/journal.pone.0285253 [Abstract]

Circulating extracellular vesicles are associated with the clinical outcomes of sepsis.,  Li, Pengfei,Wu, Yan,Goodwin, Andrew J,Wolf, Bethany,Halushka, Perry V,Wang, Hongjun,Zingarelli, Basilia,Fan, Hongkuan  (2023).  Frontiers in Immunology  (April) :  1-12 doi:10.3389/fimmu.2023.1150564 [Abstract]

Cell-Based Electrical Impedance Platform to Evaluate Zika Virus Inhibitors in Real Time.,  Oeyen, Merel,Meyen, Eef,Schols, Dominique  (2023).  Journal of visualized experiments : JoVE  (193) :  1-12 doi:10.3791/65149 [Abstract]

Melanoma Cells Produce Large Vesicular-Bodies That Cause Rapid Disruption of Brain Endothelial Barrier-Integrity and Disassembly of Junctional Proteins..,  Spurling, Dayna,Anchan, Akshata,Hucklesby, James,Finlay, Graeme,Angel, Catherine E,Graham, E Scott  (2023).  International journal of molecular sciences  24 (7) :  doi:10.3390/ijms24076082 [Abstract]

Comparative and Temporal Characterization of LPS and Blue-Light-Induced TLR4 Signal Transduction and Gene Expression in Optogenetically Manipulated Endothelial Cells.,  Stierschneider, Anna,Neuditschko, Benjamin,Colleselli, Katrin,Hundsberger, Harald,Herzog, Franz,Wiesner, Christoph  (2023).  Cells  12 (5) :  doi:10.3390/cells12050697 [Abstract]

Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome.,  de Jesus, Adriana A.,Chen, Guibin,Yang, Dan,Brdicka, Tomas,Ruth, Natasha M.,Bennin, David,Cebecauerova, Dita,Malcova, Hana,Freeman, Helen,Martin, Neil,Svojgr, Karel,Passo, Murray H.,Bhuyan, Farzana,Alehashemi, Sara,Rastegar, Andre T.,Uss, Katsiaryna,Kardava, Lela,Marrero, Bernadette,Duric, Iris,Omoyinmi, Ebun,Peldova, Petra,Lee, Chyi-Chia Richard,Kleiner, David E.,Hadigan, Colleen M.,Hewitt, Stephen M.,Pittaluga, Stefania,Carmona-Rivera, Carmelo,Calvo, Katherine R.,Shah, Nirali,Balascakova, Miroslava,Fink, Danielle L.,Kotalova, Radana,Parackova, Zuzana,Peterkova, Lucie,Kuzilkova, Daniela,Campr, Vit,Sramkova, Lucie,Biancotto, Angelique,Brooks, Stephen R.,Manes, Cameron,Meffre, Eric,Harper, Rebecca L.,Kuehn, Hyesun,Kaplan, Mariana J.,Brogan, Paul,Rosenzweig, Sergio D.,Merchant, Melinda,Deng, Zuoming,Huttenlocher, Anna,Moir, Susan L.,Kuhns, Douglas B.,Boehm, Manfred,Kramarzova, Karolina Skvarova,Goldbach-Mansky, Raphaela  (2023).  Nature Communications  14 (1502) :  doi:10.1038/s41467-023-36941-y [Abstract]

IL-33 via PKCμPRKD1 Mediated α-Catenin Phosphorylation Regulates Endothelial Cell-Barrier Integrity and Ischemia-Induced Vascular Leakage.,  Sharma, Deepti,Kaur, Geetika,Bisen, Shivantika,Sharma, Anamika,Ibrahim, Ahmed S.,Singh, Nikhlesh K  (2023).  Cells  12 (5) :  703 doi:10.3390/cells12050703 [Abstract]

E2F1 Mediates SOX17 Deficiency-Induced Pulmonary Hypertension.,  Yi, Dan,Liu, Bin,Ding, Hongxu,Li, Shuai,Li, Rebecca,Pan, Jiakai,Ramirez, Karina,Xia, Xiaomei,Kala, Mrinalini,Singh, Indrapal,Ye, Qinmao,Lee, Won Hee,Frye, Richard E.,Wang, Ting,Zhao, Yutong,Knox, Kenneth S.,Glembotski, Christopher C.,Fallon, Michael B.,Dai, Zhiyu  (2023).  (602) :  doi:10.1101/2023.02.15.528740 [Abstract]

nWASP Inhibition Increases Wound Healing via TrKb/PLCγ Signalling.,  Frugtniet, Bethan A.,Ruge, Fiona,Sanders, Andrew J.,Owen, Sioned,Harding, Keith G.,Jiang, Wen G.,Martin, Tracey A.  (2023).  Biomolecules  13 (2) :  doi:10.3390/biom13020379 [Abstract]

Presence of Polyketide Synthase (PKS) Gene and Counterpart Virulence Determinants in Klebsiella pneumoniae Strains Enhances Colorectal Cancer Progression In-Vitro.,  Kaur, Christina Parvinder,Iyadorai, Thevambiga,Sears, Cynthia,Roslani, April Camilla,Vadivelu, Jamuna,Samudi, Chandramathi  (2023).  Microorganisms  11 (2) :  1-22 doi:10.3390/microorganisms11020443 [Abstract]

Odorant Binding Causes Cytoskeletal Rearrangement , Leading to Detectable Changes in Endothelial and Epithelial Barrier Function and Micromotion.,  Curtis, Theresa M,Nilon, Annabella M,Greenberg, Anthony J,Besner, Matthew,Scibek, Jacob J,Nichols, Jennifer A,Huie, Janet L  (2023).  Biosensors  13 (3) :  doi:10.3390/bios13030329 [Abstract]

Association of Ang / Tie2 pathway mediators with endothelial barrier integrity and disease severity in COVID-19.,  Peachazepei de Moraes, Carla Roberta,Teixeira de Borba Junior, Ivanio,De Lima, Franciele,Silva, Jessica Ribeiro Alves,Bombassaro, Bruna,Palma, Andre C.,Mansour, Eli,Velloso, Licio Augusto,Orsi, Fernanda Andrade,Costa, Fabio Trindade Maranhao,De Paula, Erich Vinicius  (2023).  Frontiers in Physiology  14 (February) :  1-8 doi:10.3389/fphys.2023.1113968 [Abstract]

Activated Leukocyte Cell Adhesion Molecule ( ALCAM ), a Potential ‘ Seed ’ and ‘ Soil ’ Receptor in the Peritoneal Metastasis of Gastrointestinal Cancers.,  Yang, Yi Ming,Ye, Lin,Ruge, Fiona,Fang, Ziqian,Ji, Ke,Sanders, Andrew J,Jia, Shuqin,Hao, Chunyi,Dou, Q Ping,Ji, Jiafu,Jiang, Wen G  (2023).  International Journal of Molecular Sciences  24 (1) :  1-24 doi:10.3390/ijms24010876 [Abstract]

Plakophilin 2 regulates intestinal barrier function by modulating protein kinase C activity in vitro.,  Nagler, Simon,Ghoreishi, Yalda,Kollmann, Catherine,Kelm, Matthias,Gerull, Brenda,Waschke, Jens,Burkard, Natalie,Schlegel, Nicolas  (2022).  Tissue Barriers  11 (4) :  doi:10.1080/21688370.2022.2138061 [Abstract]

Relative Importance of Different Elements of Mitochondrial Oxidative Phosphorylation in Maintaining the Barrier Integrity of Retinal Endothelial Cells: Implications for Vascular-Associated Retinal Diseases.,  Eltanani, Shaimaa,Yumnamcha, Thangal,Gregory, Andrew,Elshal, Mahmoud,Shawky, Mohamed,Ibrahim, Ahmed S.  (2022).  Cells  11 (24) :  doi:10.3390/cells11244128 [Abstract]

Loss of SOX18/CLAUDIN5 disrupts the pulmonary endothelial barrier in ventilator-induced lung injury.,  Garcia-Flores, Alejandro E.,Gross, Christine M.,Zemskov, Evgeny A.,Lu, Qing,Tieu, Kim,Wang, Ting,Black, Stephen M.  (2022).  Frontiers in Physiology  13 (December) :  1-13 doi:10.3389/fphys.2022.1066515 [Abstract]

Real-Time Monitoring of the Cytotoxic and Antimetastatic Properties of Cannabidiol in Human Oral Squamous Cell Carcinoma Cells Using Electric Cell-Substrate Impedance Sensing.,  Huang, Chien Chu,Chiu, Shao Chih,Chao, Shih Chi,Liao, Heng Yi,Lee, Shiao Pieng,Huang, Chun Chung,Cho, Der Yang  (2022).  International journal of molecular sciences  23 (24) :  doi:10.3390/ijms232415842 [Abstract]

GPR4 in the pH- ­ dependent migration of melanoma cells in the tumor microenvironment.,  Stolwijk, Judith Anthea,Wallner, Susanne,Heider, Judith,Kurz, Bernadett,Pütz, Lisa,Michaelis, Stefanie,Goricnik, Barbara,Erl, Julia,Frank, Linda,Berneburg, Mark,Haubner, Frank,Wegener, Joachim,Schreml, Stephan  (2022).  Experimental Dermatology  (November) :  1-12 doi:10.1111/exd.14735 [Abstract]

Non-Muscle MLCK Contributes to Endothelial Cell Hyper-Proliferation through the ERK Pathway as a Mechanism for Vascular Remodeling in Pulmonary Hypertension.,  Anis, Mariam,Gonzales, Janae,Halstrom, Rachel,Baig, Noman,Humpal, Cat,Demeritte, Regaina,Epshtein, Yulia,Jacobson, Jeffrey R.,Fraidenburg, Dustin R.  (2022).  International Journal of Molecular Sciences  23 (21) :  13641 doi:10.3390/ijms232113641 [Abstract]

Key Role of Hyaluronan Metabolism for the Development of Brain Metastases in Triple-Negative Breast Cancer.,  Hamester, Fabienne,Stürken, Christine,Legler, Karen,Eylmann, Kathrin,Möller, Katrin,Roßberg, Maila,Gorzelanny, Christian,Bauer, Alexander T.,Windhorst, Sabine,Schmalfeldt, Barbara,Laakmann, Elena,Müller, Volkmar,Witzel, Isabell,Oliveira-Ferrer, Leticia  (2022).  Cells  11 (20) :  doi:10.3390/cells11203275 [Abstract]

Pirfenidone exacerbates Th2-driven vasculopathy in a mouse model of SSc-ILD.,  Birnhuber, Anna,Jandl, Katharina,Biasin, Valentina,Fließer, Elisabeth,Valzano, Francesco,Marsh, Leigh M,Krolczik, Christina,Olschewski, Andrea,Wilhelm, Jochen,Toller, Wolfgang,Heinemann, Akos,Olschewski, Horst,Wygrecka, Malgorzata,Kwapiszewska, Grazyna  (2022).  European Respiratory Journal  60 (4) :  2102347 doi:10.1183/13993003.02347-2021 [Abstract]

Analysis of Heat Flow for In Vitro Culture Monitored by Impedance Measurement.,  Kociubiński, Andrzej,Zarzeczny, Dawid,Duk, Mariusz,Bieniek, Tomasz  (2022).  Energies  15 (21) :  8231 doi:10.3390/EN15218231 [Abstract]

Protective effects of GHRH antagonists against hydrogen peroxide-induced lung endothelial barrier disruption.,  Akhter, Mohammad S,Kubra, Khadeja-Tul,Barabutis, Nektarios  (2022).  Endocrine  October 1-6 doi:10.1007/s12020-022-03226-1 [Abstract]

p73 is required for vessel integrity controlling endothelial junctional dynamics through Angiomotin.,  Maeoso-Alonso, Laura,Alonso-Olivares, Hugo,Martinez-Garcia, Nicole,Lopez-Ferreras, Lorena,Villoch-Fernandez, Javier,Puente-Santamaria, Laura,Colas-Algora, Natalia,Fernandez-Corona, Alfonso,Lorenzo-Marcos, Maria Elena,Jimenez, Benilde,Homgren, Lars,Wilhelm, Margareta,Millan, Jaime,Peso, Luis del,Claesson-Welsh, Lena,Marques, Margarita M,Marin, Maria C  (2022).  Cellular and Molecular Life Sciences  79 (10) :  535 doi:10.1007/s00018-022-04560-3 [Abstract]

Aging-regulated TUG1 is dispensable for endothelial cell function.,  Gimbel, Anna Theresa,Koziarek, Susanne,Theodorou, Kosta,Schulz, Jana Felicitas,Stanicek, Laura,Ali, Tamer,Günther, Stefan,Kumar, Sandeep,Jo, Hanjoong,Hübner, Norbert,Maegdefessel, Lars,Dimmeler, Stefanie,Heesch, Sebastiaan van,Boon, Reinier A.  (2022).  PloS one  17 (9) :  1-20 doi:10.1371/journal.pone.0265160 [Abstract]

Electric Cell-Substrate Impedance Sensing (ECIS) as a Convenient Tool to Assess the Potential of Low Molecular Fraction Derived from Medicinal Fungus Cerrena unicolor in Action on L929 and CT-26 Cell Lines.,  Prendecka-Wrobel, Monika,Pigon-Zajac, Dominika,Jaszek, Magdalena,Matuszewska, Anna,Stefaniuk, Dawid,Opielak, Grzegorz,Piotrowska, Katarzyna,Rahnama-Hezavah, Mansur,Malecka-Massalska, Teresa  (2022).  Molecules  27 (19) :  doi:10.3390/molecules27196251 [Abstract]

Apremilast exerts protective effects on stroke outcomes and blood–brain barrier (BBB) dysfunction through regulating Rho-associated protein kinase 2 expression.,  Wang, Mingyuan,Meng, Xiangyuan,Cheng, Zhihua  (2022).  Brain and Behavior  12 (9) :  e2677 doi:10.1002/brb3.2677 [Abstract]

Low Concentrations of Oxidized Phospholipids Increase Stress Tolerance of Endothelial Cells.,  Mauerhofer, Christina,Afonyushkin, Taras,Oskolkova, Olga V.,Hellauer, Klara,Gesslbauer, Bernd,Schmerda, Jasmin,Ke, Yunbo,Zimmer, Andreas,Birukova, Anna A.,Birukov, Konstantin G.,Bochkov, Valery  (2022).  Antioxidants  11 (9) :  1741 doi:10.3390/antiox11091741 [Abstract]

Lack of adducin impairs the stability of endothelial adherens and tight junctions and may be required for cAMP ‑ Rac1 ‑ mediated endothelial barrier stabilization.,  Moztarzadeh, Sina,Radeva, Mariya Y,Sepic, Sara,Schuster, Katharina,Hamad, Ibrahim,Waschke, Jens,Ponce, Alexander García  (2022).  Scientific Reports  12 (0123456789) :  1-15 doi:10.1038/s41598-022-18964-5 [Abstract]

Real-time quantification of osteoclastic resorptive activity by electric cell-substrate impedance sensing.,  Jansen, Ineke D C,Velzen, Thijs Van,Vries, Teun J De,Szulcek, Robert,van Loon, Jack J.W.A.  (2022).  Frontiers in Cell and Developmental Biology  10 (August) :  1-9 doi:10.3389/fcell.2022.921066 [Abstract]

Lung-Based, Exosome Inhibition Mediates Systemic Impacts Following Particulate Matter Exposure.,  Lopez, Keegan,Camacho, Alexandra,Jacquez, Quiteria,Amistadi, Mary Kay,Medina, Sebastian,Zychowski, Katherine  (2022).  Toxics  10 (8) :  457 doi:10.3390/toxics10080457 [Abstract]

Paracrine factors of stressed peripheral blood mononuclear cells activate pro-angiogenic and anti-proteolytic processes in whole blood cells and protect the endothelial barrier.,  Copic, Dragan,Direder, Martin,Schossleitner, Klaudia,Laggner, Maria,Klas, Katharina,Bormann, Daniel,Ankersmit, Hendrik Jan,Mildner, Michael  (2022).  Pharmaceutics  14 (8) :  1600 doi:10.3390/pharmaceutics14081600 [Abstract]

Anandamide Alters Barrier Integrity of Bovine Vascular Endothelial Cells during Endotoxin Challenge.,  Walker, Carsten C F,Sordillo, Lorraine M,Contreras, G Andres  (2022).  Antioxidants  11 (8) :  1461 doi:10.3390/antiox11081461 [Abstract]

Development of In Vitro Assays for Advancing Radioimmunotherapy against Brain Tumors.,  Walter, Yohan,Hubbard, Anne,Benoit, Allie,Jank, Erika,Salas, Olivia,Jordan, Destiny,Ekpenyong, Andrew  (2022).  Biomedicines  10 (8) :  1-25 doi:10.3390/biomedicines10081796 [Abstract]

NF- κ B-dependent repression of Sox18 transcription factor requires the epigenetic regulators histone deacetylases 1 and 2 in acute lung injury.,  Zemskov, Evgeny A,Gross, Christine M,Aggarwal, Saurabh,Zemskova, Marina A,Wu, Xiaomin,Gu, Chenxin,Wang, Ting,Tang, Haiyang,Black, Stephen M  (2022).  Frontiers in Physiology  13 1-12 doi:10.3389/fphys.2022.947537 [Abstract]

Quantitative Action Spectroscopy Reveals ARPE-19 Sensitivity to Long-Wave Ultraviolet Radiation at 350 nm and 380 nm.,  Anderson, Graham,McLeod, Andrew,Bagnaninchi, Pierre,Dhillon, Baljean  (2022).  Scientific Reports  12 (14223) :  doi:10.1038/s41598-022-17251-7 [Abstract]

Neutrophils activated by membrane attack complexes increase the permeability of melanoma blood vessels.,  Liu, Xiaobo,Wang, Yuanyuan,Bauer, Alexander T,Kirschfink, Michael,Ding, Peipei,Gebhardt, Christoffer,Borsig, Lubor  (2022).  Proceedings of the National Academy of Sciences of the United States of America  119 (33) :  doi:10.1073/pnas.2122716119 [Abstract]

Functional optimization of electric cell-substrate impedance sensing (ECIS) using human corneal epithelial cells.,  Abdul Shukkur, Ebrahim,Thanzeela, Ebrahim,Hussein, Kan,Ahmed S., Ibrahim,W. Carion, Thomas,Berger, Elizabeth  (2022).  Scientific Reports  12 (1) :  1-11 doi:10.1038/s41598-022-18182-z [Abstract]

Protective role of Cav-1 in endothelial barrier dysfunction.,  Batori, Robert K,Chen, Feng,Bordan, Zsuzsanna,Haigh, Stephen,Su, Yunchao,Verin, Alexander D,Barman, Scott A,Stepp, David W,Chakraborty, Trinad,Lucas, Rudolf,Fulton, David J R  (2022).  Frontiers in Immunology  13 (July) :  1-12 doi:10.3389/fimmu.2022.945656 [Abstract]

Melanoma Mediated Disruption of Brain Endothelial Barrier Integrity Is Not Prevented by the Inhibition of Matrix Metalloproteinases and Proteases.,  Anchan, Akshata,Finlay, Graeme,Angel, Catherine E,Hucklesby, James J W,Graham, Scott E  (2022).  Biosensors  12 (8) :  660 doi:10.3390/bios12080660 [Abstract]

Electrical cell ‑ substrate impedance sensing ( ECIS ) as a tool to study microbial ‑ cell interactions.,  Keerthi, S.,Nandkumar, A Maya  (2022).  In vitro models  (0123456789) :  doi:10.1007/s44164-022-00029-6 [Abstract]

The long non-coding RNA MEG8 induces an endothelial barrier through regulation of microRNA-370 and -494 processing.,  Kremer, Veerle,Stanicek, Laura,van Ingen, Eva,Bink, Diewertje I.,Hilderink, Sarah,Tijsen, Anke J.,Wittig, Ilka,Mägdefessel, Lars,Nossent, Anne Yaël,Boon, Reinier A.  (2022).  Journal of Cell Science  135 (12) :  doi:10.1242/jcs.259671 [Abstract]

Endothelial cell-derived extracellular vesicles impair the angiogenic response of coronary artery endothelial cells.,  Carter, Nigeste,Mathiesen, Allison H,Miller, Noel,Brown, Michael,Biancatelli, Ruben M L Colunga,Catravas, John D,Dobrian, Anca D  (2022).  Frontiers in Cardiovascular Medicine  9 (July) :  1-17 doi:10.3389/fcvm.2022.923081 [Abstract]

An Actin-, Cortactin- and Ena-VASP-Linked Complex Contributes to Endothelial Cell Focal Adhesion and Vascular Barrier Regulation.,  Mascarenhas, Joseph B,Song, Jin H,Gaber, Amir A,Jacobson, Jeffrey R,Cress, Anne E,Camp, Sara M,Dudek, Steven M,Garcia, Joe G N  (2022).  Cellular Physiology and Biochemistry  56 (4) :  329-339 doi:10.33594/000000553 [Abstract]

Metformin Enhances the Anti-Cancer Efficacy of Sorafenib via Suppressing MAPK / ERK / Stat3 Axis in Hepatocellular Carcinoma.,  Siddharth, Sumit,Kuppusamy, Panjamurthy,Wu, Qitong,Nagalingam, Arumugam,Saxena, Neeraj K,Sharma, Dipali  (2022).  International Journal of Molecular Sciences  23 (15) :  8083 doi:10.3390/ijms23158083 [Abstract]

Endothelial Barrier Disruption by Lipid Emulsions Containing a High Amount of N3 Fatty Acids (Omegaven) but Not N6 Fatty Acids (Intralipid).,  Gueguen, Emilie,Morsy, Yasser,Charl, Michael,Kramer, Stefanie D.,Zaugg, Michael,Hersberger, Martin,Rogler, Gerhard,Wawrzyniak, Marcin  (2022).  Cells  11 (14) :  doi:10.3390/cells11142202 [Abstract]

Heparan sulfate dependent binding of plasmatic von Willebrand factor to blood circulating melanoma cells attenuates metastasis.,  Wang, Yuanyuan,Liu, Xiaobo,Obser, Tobias,Bauer, Alexander T.,Heyes, Martin,Starzonek, Sarah,Zulal, Mina,Opitz, Karena,Ott, Leonie,Riethdorf, Sabine,Lange, Tobias,Pantel, Klaus,Bendas, Gerd,Schneider, Stefan W.,Kusche-Gullberg, Marion,Gorzelanny, Christian  (2022).  Matrix Biology  111 76-94 doi:10.1016/j.matbio.2022.06.002 [Abstract]

Blocking of P2X7r Reduces Mitochondrial Stress Induced by Alcohol and Electronic Cigarette Exposure in Brain.,  Mekala, Naveen,Gheewala, Nishi,Rom, Slava,Sriram, Uma,Persidsky, Yuri  (2022).  Antioxidants  11 (7) :  1328 doi:10.3390/antiox11071328 [Abstract]

In-Depth Characterization of Zika Virus Inhibitors Using Cell-Based Electircal Impedance.,  Oeyen, Merel,Meyen, Eef,Doijen, Jordi,Schols, Dominique  (2022).  Microbiology Spectrum  July doi:10.1128/spectrum.00491-22 [Abstract]

Induction of endothelial barrier dysfunction by serum factors in rats subjected to traumatic brain injury and hemorrhagic shock.,  Ke, Yunbo,Proctor, Julie,Zhang, Chenou,Medina, Juliana,Miller, Catriona,Junhyun, Kim,Grissom, Thomas,Birukova, Anna,Fiskum, Gary,Birukov, Konstantin  (2022).  Physiological Reports  10 (13) :  e15350 doi:10.14814/phy2.15350 [Abstract]

Tight junction channel regulation by interclaudin interference.,  Shashikanth, Nitesh,France, Marion M,Xiao, Ruyue,Haest, Xenia,Rizzo, Heather E,Yeste, Jose,Reiner, Johannes,Turner, Jerrold R  (2022).  Nature Communications  13 (3780) :  doi:10.1038/s41467-022-31587-8 [Abstract]

In Vitro High-Throughput Toxicological Assessment of Nanoplastics.,  Tolardo, Valentina,Magr, Davide,Fumagalli, Francesco,Cassano, Domenico,Athanassiou, Athanassia,Fragouli, Despina,Gioria, Sabrina  (2022).  Nanomaterials  12 (12) :  1947 doi:10.3390/nano12121947 [Abstract]

Comparison of anti ‑ cancer effects of novel protein disulphide isomerase ( PDI ) inhibitors in breast cancer cells characterized by high and low PDIA17 expression.,  Kurpińska, Anna,Prażmowska, Joanna Suraj,Stojak, Marta,Jarosz, Joanna,Mateuszuk, Łukasz,Andres, Ewa Niedzielska,Smolik, Magdalena,Wietrzyk, Joanna,Kalvins, Ivars,Walczak, Maria,Chłopicki, Stefan  (2022).  Cancer Cell International  22 (218) :  1-12 doi:10.1186/s12935-022-02631-w [Abstract]

The splicing‐regulatory lncRNA NTRAS sustains vascular integrity.,  Fouani, Youssef,Kirchhof, Luisa,Stanicek, Laura,Luxán, Guillermo,Heumüller, Andreas W,Knau, Andrea,Fischer, Ariane,Devraj, Kavi,John, David,Neumann, Philipp,Bindereif, Albrecht,Boon, Reinier A,Liebner, Stefan,Wittig, Ilka,Mogler, Carolin,Karimova, Madina,Dimmeler, Stefanie,Jaé, Nicolas  (2022).  EMBO reports  23 (6) :  1-13 doi:10.15252/embr.202154157 [Abstract]

Electric Cell-Substrate Impedance Sensing ( ECIS ) as a Platform for Evaluating Barrier-Function Susceptibility and Damage from Pulmonary Atelectrauma.,  Yamaguchi, Eiichiro,Yao, Joshua,Aymond, Allison,Chrisey, Douglas B,Nieman, Gary F,Bates, Jason H T,Gaver, Donald P  (2022).  Biosensors  12 (6) :  doi:10.3390/bios12060390 [Abstract]

Adiponectin Ameliorates Hyperglycemia-Induced Retinal Endothelial Dysfunction , Highlighting Pathways , Regulators , and Networks.,  Bushra, Sumbul,Al-sadeq, Duaa W,Bari, Redwana,Sahara, Afifah,Fadel, Amina,Rizk, Nasser  (2022).  Journal of Inflammation Research  15 (January) :  3135-3166 doi:10.2147/JIR.S358594 [Abstract]

EGFR R521K Polymorphism Is Not a Major Determinant of Clinical Cetuximab Resistance in Head and Neck Cancer.,  Mihaly, Cserepes,Nelhubel, Gyogyi A.,Meilinger-Dobra, Monika,Herczeg, Adrienn,Turk, Dora,Hegedus, Zita,Svajda, Laura,Raso, Erzsebet,Ladanyi, Andrea,Csiko, Kristof Gyorgy,Kenessey, Istvan,Szoor, Arpad,Vereb, Gyorgy,Remenar, Eva,Tovari, Jozsef  (2022).  Cancers  14 (10) :  2407 doi:10.3390/cancers14102407 [Abstract]

Real-Time Monitoring the Cytotoxic Effect of Andrographolide on Human Oral Epidermoid Carcinoma Cells.,  Liao, Heng-yi,Huang, Chun-chung,Chao, Shih-chi,Chiang, Chien-ping,Tang, Bo-hsuan,Lee, Shiao-Pieng,Wang, Jehng-Kang  (2022).  Biosensors  12 (5) :  304 doi:10.3390/bios12050304 [Abstract]

Hemin Induced Endothelial Dysfunction and Endothelial to Mesenchymal Transition Contributes to the Pathogenesis of Pulmonary Hypertension Due to Chronic Hemolysis.,  Gonzales, Janae,Holbert, Kelsey,Czysz, Kamryn,George, Joseph,Fernandes, Caroline,Fraidenburg, Dustin R.  (2022).  International Journal of Molecular Sciences  23 (9) :  4763 doi:10.3390/ijms23094763 [Abstract]

Preclinical In Vitro Model to Assess the Changes in Permeability and Cytotoxicity of Polarized Intestinal Epithelial Cells during Exposure Mimicking Oral or Intravenous Routes : An Example of Arsenite Exposure.,  Parajuli, Pravin,Gokulan, Kuppan,Khare, Sangeeta  (2022).  International Journal of Molecular Sciences  23 (9) :  4851 doi:10.3390/ijms23094851 [Abstract]

Antiproliferative Properties of Triterpenoids by ECIS Method — A New Promising Approach in Anticancer Studies ?.,  Hordyjewska, Anna,Prendecka-Wrobel, Monika,Kurach, Łukasz,Horecka, Anna,Olszewska, Anna,Pigon-Zajac, Dominika,Malecka-Massalska, Teresa,Kurzepa, Jacek  (2022).  Molecules  27 (10) :  3150 doi:10.3390/molecules27103150 [Abstract]

The Link Between 15-F 2t -Isoprostane Activity and Acute Bovine Endothelial Inflammation Remains Elusive.,  Putman, Ashley K,Sordillo, Lorraine M,Contreras, G Andres  (2022).  Frontiers in Veterinary Science  9 (April) :  873544 doi:10.3389/fvets.2022.873544 [Abstract]

Heparan sulfate mimetic fucoidan restores the endothelial glycocalyx and protects against dysfunction induced by serum of COVID-19 patients on ICU.,  Yuan, Lushun,Cheng, Shuzhen,Sol, Wendy M.P.J.,van der Velden, Anouk I.M.,Vink, Hans,Rabelink, Ton J.,van den Berg, Bernard M.  (2022).  ERJ Open Research  (March) :  00652-2021 doi:10.1183/23120541.00652-2021 [Abstract]

ECIS Based Electric Fence Method for Measurement of Human Keratinocyte Migration on Different Substrates.,  Hung, Yu-han,Chiu, Wei-chih,Fuh, Shyh-rong,Lai, Yi-ting,Tung, Tse-hua,Huang, Chun-chung,Lo, Chun-Min  (2022).  Biosensors  12 (5) :  1-15 doi:10.3390/bios12050293 [Abstract]

Oral administration of turmeric ‑ derived exosome ‑ like nanovesicles with anti ‑ inflammatory and pro ‑ resolving bioactions for murine colitis therapy.,  Liu, Cui,Yan, Xiangji,Zhang, Yujie,Yang, Mei,Ma, Yana,Zhang, Yuanyuan,Xu, Qiuran,Tu, Kangsheng,Zhang, Mingzhen  (2022).  Journal of Nanobiotechnology  20 (206) :  1-17 doi:10.1186/s12951-022-01421-w [Abstract]

The ATX – LPA Axis Regulates Vascular Permeability during Cerebral Ischemic-Reperfusion.,  Bhattarai, Susmita,Sharma, Sudha,Subedi, Utsab,Ara, Hosne,Shum, Alika,Milena, Murov,Bhuiyan, Md. Shenuarin,Kidambi, Srivatsan,Sun, Hong,Miriyala, Sumitra,Panchatcharam, Manikandan  (2022).  International Journal of Molecular Sciences  23 (8) :  4138 [Abstract]

Endothelial cells of pulmonary origin display unique sensitivity to the bacterial endotoxin lipopolysaccharide.,  Morsing, Sofia K. H.,Zeeuw van der Laan, Eveline,Stalborch, Anne‐Marieke D.,Buul, Jaap D.,Vlaar, Alexander P. J.,Kapur, Rick  (2022).  Physiological Reports  10 (8) :  1-14 doi:10.14814/phy2.15271 [Abstract]

Differential Effects of Cytopathic Hypoxia on Human Retinal Endothelial Cellular Behavior : Implication for Ischemic Retinopathies.,  El-tanani, Shaimaa,Yumnamcha, Thangal,Singh, Lalit Pukhrambam,Ibrahim, Ahmed S  (2022).  International Journal of Molecular Sciences  23 (8) :  1-14 doi:10.3390/ijms23084274 [Abstract]

TNF- α Induced Myotube Atrophy in C2C12 Cell Line Uncovers Putative Inflammatory-Related lncRNAs Mediating Muscle Wasting.,  Powrozek, Tomasz,Pgion-Zajac, Dominika,Mazurek, Marcin,Otieno, Michael Ochieng,Rahnama-Hezavah, Mansur,Malecka-Massalska, Teresa  (2022).  International journal of molecular medicine  23 (7) :  3878 doi:10.3390/ijms23073878 [Abstract]

Cell-Crossing Functional Network Driven by microRNA-125a Regulates Endothelial Permeability and Monocyte Trafficking in Acute In flammation.,  Müller, Martin Bernhard,Hübner, Max,Li, Lei,Tomasi, Stephanie,Ließke, Valena,Ef, David,Hirschberger, Simon,Pogoda, Kristin,Sperandio, Markus,Kreth, Simone  (2022).  Frontiers in Immunology  13 (March) :  1-15 doi:10.3389/fimmu.2022.826047 [Abstract]

HSP90 Inhibitors Modulate SARS-CoV-2 Spike Protein Subunit 1-Induced Human Pulmonary Microvascular Endothelial Activation and Barrier Dysfunction.,  Colunga Biancatelli, Ruben Manuel Luciano,Solopov, Pavel A.,Gregory, Betsy,Khodour, Yara,Catravas, John D.  (2022).  Frontiers in Physiology  13 (March) :  doi:10.3389/fphys.2022.812199 [Abstract]

The amyloid peptide β disrupts intercellular junctions and increases endothelial permeability in a NADPH oxidase 1-dependent manner.,  Tarafdar, Anuradha,Wolska, Nina,Krisp, Christoph,Schlüter, Hartmut,Pula, Giordano  (2022).  Redox Biology  52 (December 2021) :  102287 doi:10.1016/j.redox.2022.102287 [Abstract]

Aldehyde trapping by ADX-102 is protective against cigarette smoke and alcohol-mediated lung cell injury.,  Ochoa, Carmen A.,Nissen, Claire,Mosley, Deanna D.,Bauer, Christopher D.,Jordan, Destiny,Bailey, Kristina L.,Wyatt, Todd A.  (2022).  Biomolecules  12 (3) :  393 doi:10.3390/biom12030393 [Abstract]

The Heat Shock Protein 90 Inhibitor, AT13387, Protects the Alveolo-Capillary Barrier and Prevents HCl-Induced Chronic Lung Injury and Pulmonary Fibrosis.,  Biancatelli, Ruben M L Colunga,Solopov, Pavel,Dimitropoulou, Christiana,Gregory, Betsy,Day, Tierney,Catravas, John D  (2022).  Cells  11 (6) :  1-12 doi:10.3390/cells11061046 [Abstract]

Direct Thrombin Inhibitor Dabigatran Compromises Pulmonary Endothelial Integrity in a Murine Model of Breast Cancer Metastasis to the Lungs; the Role of Platelets and Inflammation-Associated Haemostasis.,  Smeda, Marta,Stojak, Marta,Przyborowski, Kamil,Sternak, Magdalena,Suraj-Prazmowska, Joanna,Kus, Kamil,Derszniak, Katarzyna,Jasztal, Agnieszka,Kij, Agnieszka,Kurpinska, Anna,Kieronska-Rudek, Anna,Wojnar-Lason, Kamila,Buczek, Elzbieta,Mohaissen, Tasnim,Chlopicki, Stefan  (2022).  Frontiers in Pharmacology  13 (February) :  1-15 doi:10.3389/fphar.2022.834472 [Abstract]

Isolation of Primary Patient-specific Aortic Smooth Muscle Cells and Semiquantitative Real-time Contraction Measurements In Vitro.,  Bogunovic, Natalija,Rombouts, Karlijn B,Yeung, Kak Khee  (2022).  JoVE  doi:10.3791/63122 [Abstract]

Endothelial Superoxide Dismutase 2 is Decreased in Sickle Cell Disease and Regulates Fibronectin Processing.,  Dosunmu-Ogunbi, Atinuke,Yuan, Shuai,Shiwarski, Daniel J,Tashman, Joshua W,Reynolds, Michael,Feinberg, Adam,Novelli, Enrico M,Shiva, Sruti,Straub, Adam C  (2022).  Function  3 (October 2021) :  1-12 doi:10.1093/function/zqac005 [Abstract]

Integrin Beta 4E Promotes Endothelial Phenotypic Changes and Attenuates Lung Endothelial Cell Inflammatory Responses.,  Chen, Weiguo,Gard, Jamie M. C.,Epshtein, Yulia,Camp, Sara M.,Garcia, Joe G. N.,Jacobson, Jeffrey R.,Cress, Anne E.  (2022).  Frontiers in Physiology  13 (February) :  1-10 doi:10.3389/fphys.2022.769325 [Abstract]

The relation between age and airway epithelial barrier function.,  de Vries, M.,Nwozor, K. O.,Muizer, K.,Wisman, M.,Timens, W.,van den Berge, M.,Faiz, A.,Hackett, T.-L.,Heijink, I. H.,Brandsma, C. A.  (2022).  Respiratory Research  23 (1) :  1-9 doi:10.1186/s12931-022-01961-7 [Abstract]

Tunicamycin Protects against LPS-Induced Lung Injury.,  Kubra, Khadeja-Tul,Uddin, Mohammad A.,Barabutis, Nektarios  (2022).  Pharmaceuticals  15 (2) :  134 doi:10.3390/ph15020134 [Abstract]

Hepatitis A Virus Cellular Receptor 1 ( HAVcr-1 ) Initiates Prostate Cancer Progression in Human Cells via Hepatocyte Growth Factor ( HGF ) -Induced Changes in Junctional Integrity.,  Telford, Emily A,Sanders, Andrew J,Owen, Sioned,Ruge, Fiona,Harrison, Gregory M,Jiang, Wen G,Martin, Tracey A  (2022).  Biomolecules  12 (2) :  338 doi:10.3390/biom12020338 [Abstract]

Blood-Brain Barrier Disruption Mediated by FFA1 Receptor — Evidence Using Miniscope.,  Lindenau, Kristen L,Barr, Jeffrey L,Higgins, Christopher R,Sporici, Kevin T,Brailoiu, Eugen,Brailoiu, Gabriela C  (2022).  International Journal of Molecular Sciences  23 (4) :  2258 doi:10.3390/ijms23042258 [Abstract]

Meningitic Escherichia coli-Induced Interleukin-17A Facilitates Blood–Brain Barrier Disruption via Inhibiting Proteinase 3/Protease-Activated Receptor 2 Axis.,  Xu, Bojie,Chen, Jiaqi,Fu, Jiyang,Yang, Ruicheng,Yang, Bo,Huo, Dong,Tan, Chen,Chen, Huanchun,Wang, Xiangru  (2022).  Frontiers in Cellular Neuroscience  16 (February) :  1-12 doi:10.3389/fncel.2022.814867 [Abstract]

In Vitro Methods for Measuring the Permeability of Cell Monolayers.,  Bednarek, Radoslaw  (2022).  Methods and Protocols  5 (1) :  17 doi:10.3390/mps5010017 [Abstract]

Elevated Cytokine Levels in Plasma of Patients with SARS-CoV-2 Do Not Contribute to Pulmonary Microvascular Endothelial.,  Kovacs-kasa, Anita,Zaied, Abdelrahman A,Leanhart, Silvia,Koseoglu, Murat,Sridhar, Supriya,Lucas, Rudolf,Fulton, David J,Vazquez, Jose A,Annex, Brian H  (2022).  Microbiology Spectrum  10 (1) :  1-16 doi:10.1128/spectrum.01671-21 [Abstract]

Allicin Improves Intestinal Epithelial Barrier Function and Prevents LPS-Induced Barrier Damages of Intestinal Epithelial Cell Monolayers.,  Gao, Jingxia,Song, Guanzhong,Shen, Haibo,Wu, Yiming,Zhao, Chongqi,Zhang, Zhuo,Jiang, Qian,Li, Xilong,Ma, Xiaokang,Tan, Bie,Yin, Yulong  (2022).  Frontiers in Immunology  13 (February) :  1-12 doi:10.3389/fimmu.2022.847861 [Abstract]

pH-Sensing G Protein-Coupled Receptor OGR1 ( GPR68 ) Expression and Activation Increases in Intestinal Inflammation and Fibrosis.,  Valliere, Cheryl De,Cosin-Roger, Jesus,Baebler, Katharina,Schoepflin, Anja,Mamie, C,Mollet, Michelle,Schuler, Cordelia,Bengs, Susan,Lang, Silvia,Scharl, Michael,Seuwen, Klaus,Ruiz, Pedro A,Hausmann, Martin,Rogler, Gerhard  (2022).  International journal of molecular sciences  23 (3) :  1419 doi:10.3390/ijms23031419 [Abstract]

Insights into the Steps of Breast Cancer – Brain Metastases Development : Tumor Cell Interactions with the Blood-Brain Barrier.,  Hamester, Fabienne,Stürken, Christine,Saygi, Ceren,Qi, Minyue,Legler, Karen,Gorzelanny, Christian,Robador, Jos R,Schmalfeldt, Barbara,Laakmann, Elena,Müller, Volkmar,Witzel, Isabell,Oliveira-Ferrer, Leticia  (2022).  International Journal of Molecular Sciences  23 (3) :  1900 doi:10.3390/ijms23031900 [Abstract]

Biological Activity of an Epilobium angustifolium L. (Fireweed) Infusion after In Vitro Digestion.,  Kowalik, Klaudia,Polak-berecka, Magdalena,Prendecka-Wrobel, Monika,Pigon-Zajac, Dominika,Niedzwiedz, Iwona,Szwajgier, Dominik,Baranowska-Wojcik, Ewa,Wasko, Adam  (2022).  Molecules  27 (3) :  1006 doi:10.3390/molecules27031006 [Abstract]

The multitargeted receptor tyrosine kinase inhibitor sunitinib induces resistance of HER2 positive breast cancer cells to trastuzumab-mediated ADCC.,  Guti, Eliza,Regdon, Zsolt,Sturniolo, Isotta,Kiss, Alexandra,Kovács, Katalin,Demény, Máté,Szöőr, Árpád,Vereb, György,Szöllősi, János,Hegedűs, Csaba,Polgár, Zsuzsanna,Virág, László  (2022).  Cancer Immunology, Immunotherapy  doi:10.1007/s00262-022-03146-z [Abstract]

AICAR Protects Vascular Endothelial Cells from Oxidative Injury Induced by the Long-Term Palmitate Excess.,  Samsonov, Mikhail V,Podkuychenko, Nikita V,Khapchaev, Asker Y,Efremov, Eugene E,Yanushevskaya, Elena V,Vlasik, Tatiana N,Lankin, Vadim Z,Stafeev, Iurii S,Skulachev, Maxim V,Shestakova, Marina V,Vorotnikov, Alexander V,Shirinsky, Vladimir P  (2022).  International Journal of Molecular Sciences  23 (1) :  211 doi:10.3390/ijms23010211 [Abstract]

Distinct Mechanisms of Human Retinal Endothelial Barrier Modulation In Vitro by Mediators of Diabetes and Uveitis.,  Rudraraju, Madhuri,Narayanan, S Priya,Somanath, Payaningal R  (2022).  Life (Basel)  12 (1) :  33 doi:10.3390/life12010033 [Abstract]

Inhibiting TLR7 Expression in the Retinal Pigment Epithelium Suppresses Experimental Autoimmune Uveitis.,  Lo, Sheng-Min,Hwang, Yih-Shiou,Liu, Chao-Lin,Shen, Chia-Ning,Hong, Wei-Hsin,Yang, Wei-Cheng,Lee, Meng-Hua,Shen, Chia-Rui  (2022).  Frontiers in Immunology  12 (January) :  1-13 doi:10.3389/fimmu.2021.736261 [Abstract]

MEG8 regulates Tissue Factor Pathway Inhibitor 2 ( TFPI2 ) expression in the endothelium.,  Kremer, Veerle,Bink, Diewertje I,Stanicek, Laura,Ingen, Eva Van,Gimbel, Theresa,Hilderink, Sarah,Gunther, Stefan,Nossent, Anne Yael,Boon, Reinier A.  (2022).  Scientific Reports  12 (843) :  doi:10.1038/s41598-022-04812-z [Abstract]

Electric cell-substrate impedance sensing in kidney research.,  Kociubinski, Andrzej  (2021).  Journal of Electrical Bioimpedance  12 (1) :  163-168 doi:10.2478/joeb-2021-0019 [Abstract]

Silencing Akt1 enhances the resistance of prostate cancer cells to starvation and inhibits starvation-induced lung metastasis through epithelial–mesenchymal transition in prostate cancer.,  Yang, Mei,Liu, Hui,Qiu, Guo-Ping,Gao, Fei  (2021).  Medical Oncology  39 (1) :  8 doi:10.1007/s12032-021-01600-z [Abstract]

Complement activation induces excessive T cell cytotoxicity in severe COVID-19.,  Georg, Phillip,Astaburuaga-Garcia, Rosario,Bonaguro, Lorenzo,Brumhard, Sophia,Michalick, Laura,Lippert, Lena J.,Kostevc, Tomislav,Gabel, Christiane,Schnelder, Maria,Streitz, Mathias,Demichev, Vadim,Gemund, Ioanna,Barone, Matthias,Tober-Lau, Pinkus,Helbig, Elisa T.,Hillus, David,Petrov, Lev,Stein, Julia,Dey, Hannah-Philine,Paclik, Daniela,Iwert, Christina,Mulleder, Michael,Aulakh, Simran Kaur,Djudjaj, Sonja,Bulow, Roman D.,Mei, Henrik E.,Schulz, Axel R.,Thiel, Andreas,Hippenstiel, Stefan,Saliba, Antoine-Emmanuel,Eils, Roland,Lehmann, Irina,Mall, Marcus A.,Strciker, Sebastian,Rohmel, Jobst,Corman, Victor M.,Beule, Dieter,Wyler, Emanuel,Landthaler, Markus,Obermayer, Benedikt,Stillfried, Saskia von,Boor, Peter,Demir, Munevver,Wesselmann, Hans,Suttorp, Norbert,Uhrig, Alexander,Muller-Redetzky, Holger,Nattermann, Jacob,Kuebler, Wolfgang M.,Meisel, Christian,Ralser, Markus,Schultze, Joachim L.,Aschenbrenner, Anna C.,Thibeault, Charlotte,Kurth, Florian,Sander, Leif E.,Bluthgen, Nils,Sawitzki, Birgit  (2021).  Cell  (December) :  doi:10.1016/j.cell.2021.12.040 [Abstract]

Activated leukocyte cell adhesion molecule ( ALCAM )/ CD166 in pancreatic cancer , a pivotal link to clinical outcome and vascular embolism.,  Yang, Yiming,Sanders, Andrew J,Ruge, Fiona,Dong, Xuefei,Cui, Yuxin,Dou, Qing Ping,Jia, Shuqin,Hao, Chunyl,Ji, Jiafu,Jiang, Wen G  (2021).  American Journal of Cancer Research  11 (12) :  5917-5932 [Abstract]

Essential Role of Rho-Associated Kinase in ABO Immune Complex-Mediated Endothelial Barrier Disruption.,  Mcrae, Hannah L,Millar, Michelle Warren,Slavin, Spencer A,Blumberg, Neil,Rahman, Arshad,Refaai, Majed A  (2021).  Biomedicines  9 (12) :  1851 doi:10.3390/biomedicines9121851 [Abstract]

Can ECIS Biosensor Technology Be Used to Measure the Cellular Responses of Glioblastoma Stem Cells?.,  Robilliard, Laverne Diana,Yu, Jane,Jun, Sung-Min,Anchan, Akshata,Finlay, Graeme,Angel, Catherine E.,Graham, Euan Scott  (2021).  Biosensors  11 (12) :  498 doi:10.3390/bios11120498 [Abstract]

Deciphering the role of extracellular vesicles derived from ZIKV-infected hcMEC/D3 cells on the blood–brain barrier system.,  Fikatas, Antonios,Dehairs, Jonas,Noppen, Sam,Doijen, Jordi,Vanderhoydonc, Frank,Meyen, Eef,Swinnen, Johannes V.,Pannecouque, Christophe,Schols, Dominique  (2021).  Viruses  13 (12) :  doi:10.3390/v13122363 [Abstract]

Circulating Levels of Ang/Tie2 and VEGF-a Pathway Mediators Are Associated with Clinical Severity, Endothelial Barrier Disruption and Coagulation Activation in COVID-19.,  Peachazepei de Moraes, Carla Roberta,Teixeira de Borba Junior, Ivanio,Lima, Franciele de,Barbosa, Mayck Silva,Huber, Stephany Cares,Palma, Andre C.,Nunes, Thyago A.,Ulaf, Rasia G.,Ribeiro, Luciana C.,Bernandes, Ana Flavia,Bombassaro, Bruna,Dertkigil, Sergio S.,Moretti, Maria Luiza,Bizzacchi, Joyce Annichino,Mansour, Eli,Velloso, Licio Augusto,Costa, Fabio Trindade Maranhao,Orsi, Fernanda Andrade,De Paula, Erich V.  (2021).  Blood  (138) :  2073 doi:10.1182/blood-2021-152771 [Abstract]

Upregulation of Aquaporin 1 Mediates Increased Migration and Proliferation in Pulmonary Vascular Cells From the Rat SU5416/Hypoxia Model of Pulmonary Hypertension.,  Yun, Xin,Philip, Nicolas M.,Jiang, Haiyang,Smith, Zion,Huetsch, John C.,Damarla, Mahendra,Suresh, Karthik,Shimoda, Larissa A.  (2021).  Frontiers in Physiology  12 (December) :  doi:10.3389/fphys.2021.763444 [Abstract]

Chronic Porphyromonas gingivalis lipopolysaccharide induces adverse myocardial infarction wound healing through activation of CD8 + T cells.,  Zaidi, Yusra,Corker, Alexa,Vasileva, Valeriia Y.,Oviedo, Kimberly,Graham, Connor,Wilson, Kyrie,Martino, John,Troncoso, Miguel,Broughton, Philip,Ilatovskaya, Daria V.,Lindsey, Merry L.,DeLeon-Pennell, Kristine Y.  (2021).  American Journal of Physiology-Heart and Circulatory Physiology  321 (5) :  H948-H962 doi:10.1152/ajpheart.00082.2021 [Abstract]

Recent Advances in Electrical Impedance Sensing Technology for Single-Cell Analysis.,  Zhang, Zhao,Huang, Xiaowen,Liu, Ke,Lan, Tiancong,Wang, Zixin,Zhu, Zhen  (2021).  Biosensors  11 (11) :  470 doi:10.3390/bios11110470 [Abstract]

Paracrine Regulation of Alveolar Epithelial Damage and Repair Responses by Human Lung-Resident Mesenchymal Stromal Cells.,  Kruk, Dennis M. L. W.,Wisman, Marissa,Noordhoek, Jacobien A.,Nizamoglu, Mehmet,Jonker, Marnix R.,de Bruin, Harold G.,Arevalo Gomez, Karla,ten Hacken, Nick H. T.,Pouwels, Simon D.,Heijink, Irene H.  (2021).  Cells  10 (11) :  2860 doi:10.3390/cells10112860 [Abstract]

Syncytialization alters the extracellular matrix and barrier function of placental trophoblasts.,  Moore, Kyle H,Murphy, Haley A,Chapman, Heather,George, Eric M  (2021).  American Journal of Physiology Cell Physiology  321 (4) :  doi:10.1152/ajpcell.00177.2021 [Abstract]

Total parasite biomass but not peripheral parasitaemia is associated with endothelial and haematological perturbations in Plasmodium vivax patients.,  Silva-, João L,Dos-, João C K,Venugopal, Kannan,Lima, Diogenes,Nakaya, Helder I,Paula, Erich V De,Lopes, Stefanie C P,Lacerda, Marcus V G,Marti, Matthias,Costa, Fabio T M  (2021).  eLife  10 1-25 doi:10.7554/eLife.71351 [Abstract]

Desmoglein2 Regulates Claudin2 Expression by Sequestering PI-3-Kinase in Intestinal Epithelial Cells.,  Burkard, Natalie,Meir, Michael,Kannapin, Felix,Otto, Christoph,Petzke, Maximilian,Germer, Christoph-Thomas,Waschke, Jens,Schlegel, Nicolas  (2021).  Frontiers in Immunology  12 (September) :  1-17 doi:10.3389/fimmu.2021.756321 [Abstract]

Maraviroc Prevents HCC Development by Suppressing Macrophages and the Liver Progenitor Cell Response in a Murine Chronic Liver Disease Model.,  Passman, Adam M,Strauss, Robyn P,McSpadden, Sarah B,Finch-Edmondson, Megan,Andrewartha, Neil,Woo, Ken H,Diepeveen, Luke A,Zhao, Weihao,Fernandez-Irigoyen, Joaquin,Santamaria, Enrique,Medina-ruiz, Laura,Szpakowska, Martyna,Chevigne, Andy,Park, Hyerin,Carlessi, Rodrigo,Tirnitz-parker, Janina E E,Blanco, Jose R,London, Roslyn,Callus, Bernard A,Elsegood, Caryn L,Baker, Murray V,Martinez, Alfredo,Yeoh, George C T  (2021).  Cancers  13 (19) :  doi:10.3390/cancers13194935 [Abstract]

Label-free cell based impedance measurements of ZnO nanoparticles—human lung cell interaction: a comparison with MTT, NR, Trypan blue and cloning efficiency assays.,  Bozzuto, Giuseppina,D’Avenio, Giuseppe,Condello, Maria,Sennato, Simona,Battaglione, Ezio,Familiari, Giuseppe,Molinari, Agnese,Grigioni, Mauro  (2021).  Journal of Nanobiotechnology  19 (1) :  1-23 doi:10.1186/s12951-021-01033-w [Abstract]

Proteomics analysis identifies PEA-15 as an endosomal phosphoprotein that regulates α5β1 integrin endocytosis.,  Caliva, Maisel J.,Yang, Won Seok,Young-Robbins, Shirley,Zhou, Ming,Yoon, Hana,Matter, Michelle L.,Grimes, Mark L.,Conrads, Thomas,Ramos, Joe William  (2021).  Scientific Reports  11 (1) :  doi:10.1038/s41598-021-99348-z [Abstract]

EVL is a novel focal adhesion protein involved in the regulation of cytoskeletal dynamics and vascular permeability.,  Mascarenhas, Joseph B,Gaber, Amir A,Larrinaga, Tania M,Mayfield, Rachel,Novak, Stefanie,Camp, Sara M.,Gregorio, Carol,Jacobson, Jeffrey,Cress, Anne E,Dudek, Steven,Garcia, Joe G. N.  (2021).  Pulmonary Circulation  204589402110490 doi:10.1177/20458940211049002 [Abstract]

Comparison of polynomial fitting versus single time point analysis of ECIS data for barrier assessment.,  Suresh, Karthik,Servinsky, Laura,Johnston, Laura,Punjabi, Naresh M.,Dudek, Steven M.,Damarla, Mahendra  (2021).  Physiological Reports  9 (19) :  1-8 doi:10.14814/phy2.14983 [Abstract]

TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity.,  Bi, Jiacheng,Cheng, Chen,Zheng, Chaoyue,Huang, Chen,Zheng, Xiaohu,Wan, Xiaochun,Chen, Youhai H.,Tian, Zhigang,Sun, Haoyu  (2021).  Science Advances  7 (38) :  1-13 doi:10.1126/sciadv.abi6515 [Abstract]

BRCC3 Promotes Tumorigenesis of Bladder Cancer by Activating the NF-κB Signaling Pathway Through Targeting TRAF2.,  Tao, Huangheng,Liao, Yixiang,Yan, Youji,He, Zhiwen,Zhou, Jiajie,Wang, Xinghuan,Peng, Jianping,Li, Shangze,Liu, Tao  (2021).  Frontiers in Cell and Developmental Biology  9 (September) :  1-11 doi:10.3389/fcell.2021.720349 [Abstract]

Endothelial-Derived Extracellular Vesicles Induce Cerebrovascular Dysfunction in Inflammation.,  Roig-carles, David,Willms, Eduard,Fontijn, Ruud D,Martinez-pacheco, Sarai,Mäger, Imre,Vries, Helga E De,Hirst, Mark,Sharrack, Basil,Male, David K,Hawkes, Cheryl A,Romero, Ignacio A  (2021).  Pharmaceutics  13 (9) :  1525 doi:10.3390/pharmaceutics13091525 [Abstract]

Serum Vitamin D Is Associated with Antioxidant Potential in Peri-Parturient Cows.,  Strickland, Jaimie M,Wisnieski, Lauren,Mavangira, Vengai,Sordillo, Lorraine M  (2021).  Antioxidants  10 (9) :  1420 doi:10.3390/antiox10091420 [Abstract]

The Short-Chain Fatty Acid Butyrate Attenuates Pulmonary Vascular Remodeling and Inflammation in Hypoxia-Induced Pulmonary Hypertension.,  Karoor, Vijaya,Strassheim, Derek,Sullivan, Timothy,Verin, Alexander,Umapathy, Nagavedi S,Dempsey, Edward C,Frank, Daniel N,Stenmark, Kurt R,Gerasimovskaya, Evgenia  (2021).  International Journal of Molecular Sciences  22 (18) :  1-19 doi:10.3390/ijms22189916 [Abstract]

Haloperidol Attenuates Lung Endothelial Cell Permeability In Vitro and In Vivo.,  Colamonici, Marco A.,Epshtein, Yulia,Chen, Weiguo,Jacobson, Jeffrey R.  (2021).  Cells  10 (9) :  2186 doi:10.3390/cells10092186 [Abstract]

Cartilage Acidic Protein a Novel Therapeutic Factor to Improve Skin Damage Repair ?.,  Felix, Rute Castelo,Anjos, Liliana,Costa, Rita Alves,Letsiou, Sophia,Power, Deborah Mary  (2021).  Marine Drugs  19 (10) :  541 doi:10.3390/md19100541 [Abstract]

The Role of the Wnt Pathway in VEGF/Anti-VEGF-Dependent Control of the Endothelial Cell Barrier.,  Li, Yueru,Baccouche, Basma,Olayinka, Olamide,Serikbaeva, Anara,Kazlauskas, Andrius  (2021).  Investigative Opthalmology & Visual Science  62 (12) :  17 doi:10.1167/iovs.62.12.17 [Abstract]

Cocaine augments neuro-inflammation via modulating extracellular vesicle release in HIV-1 infected immune cells.,  Narayanan, Manojkumar,Kulkarni, Rutuja,Jiang, Shuxian,Kashanchi, Fatah,Prasad, Anil  (2021).  Retrovirology  18 (1) :  1-17 doi:10.1186/s12977-021-00570-4 [Abstract]

Brain Microvascular Endothelial Cell-Derived HMGB1 Facilitates Monocyte Adhesion and Transmigration to Promote JEV Neuroinvasion.,  Zou, Song-Song,Zou, Qing-Cui,Xiong, Wen-Jing,Cui, Ning-Yi,Wang, Ke,Liu, Hao-Xuan,Lou, Wen-Juan,Higazy, Doaa,Zhang, Ya-Ge,Cui, Min  (2021).  Frontiers in Cellular and Infection Microbiology  11 (August) :  1-13 doi:10.3389/fcimb.2021.701820 [Abstract]

Advanced optogenetic-based biosensing and related biomaterials.,  Gheorghiu, Mihaela,Polonschii, Cristina,Popescu, Octavian,Gheorghiu, Eugen  (2021).  Materials  14 (15) :  5-12 doi:10.3390/ma14154151 [Abstract]

Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration.,  Cao, Qi,Wei, Wenbin,Wang, Huan,Wang, Zesong,Lv, Yujin,Dai, Menghong,Tan, Chen,Chen, Huanchun,Wang, Xiangru  (2021).  Virulence  12 (1) :  2296-2313 doi:10.1080/21505594.2021.1966996 [Abstract]

Pulmonary delivery of the broad-spectrum matrix metalloproteinase inhibitor marimastat diminishes multiwalled carbon nanotube-induced circulating bioactivity without reducing pulmonary inflammation.,  Young, Tamara L.,Mostovenko, Ekaterina,Denson, Jesse L.,Begay, Jessica G.,Lucas, Selita N.,Herbert, Guy,Zychowski, Katherine,Hunter, Russell,Salazar, Raul,Wang, Ting,Fraser, Kelly,Erdely, Aaron,Ottens, Andrew K.,Campen, Matthew J.  (2021).  Particle and Fibre Toxicology  18 (1) :  1-16 doi:10.1186/s12989-021-00427-w [Abstract]

Light-Inducible Spatio-Temporal Control of TLR4 and NF- κ B-Gluc Reporter in Human Pancreatic Cell Line.,  Stierschneider, Anna,Grünstäudl, Petra,Colleselli, Katrin,Atzler, Josef,Klein, Christian T,Hundsberger, Harald,Wiesner, Christoph  (2021).  International Journal of Molecular Sciences  22 (17) :  9232 doi:10.3390/ijms22179232 [Abstract]

Transcriptome Differences in Pig Tracheal Epithelial Cells in Response to Pasteurella Multocida Infection.,  Wang, Xueying,Wang, Fei,Lin, Lin,Liang, Wan,Liu, Songtao,Hua, Lin,Wang, Xiangru,Chen, Huanchun,Peng, Zhong,Wu, Bin  (2021).  Frontiers in Veterinary Science  8 (August) :  1-11 doi:10.3389/fvets.2021.682514 [Abstract]

A short review on cell-based biosensing: challenges and breakthroughs in biomedical analysis.,  Gheorghiu, Mihaela  (2021).  The Journal of Biomedical Research  35 (4) :  255 doi:10.7555/jbr.34.20200128 [Abstract]

Increase in Blood – Brain Barrier Permeability is Modulated by Tissue Kallikrein via Activation of Bradykinin B1 and B2 Receptor-Mediated Signaling.,  Zhang, Qin,Tan, Juan,Chen, Chao,Wu, Bin,Ke, Xijian,Wu, Rongxue,Ran, Xiao  (2021).  Journal of Inflammation Research  (14) :  4283-4297 doi:10.2147/JIR.S322225 [Abstract]

Modelling and Differential Quantification of Electric Cell-Substrate Impedance Sensing Growth Curves.,  Ronja, Anna,Binder, Dorothea,Spiess, Andrej-nikolai,Pfaffl, Michael W  (2021).  Sensors  21 (16) :  5286 doi:10.3390/s21165286 [Abstract]

Syncytialization alters the extracellular matrix and barrier function of placental trophoblasts.,  Moore, Kyle H,Murphy, Hayley A,Chapman, Heather,George, Eric M  (2021).  American Journal of Physiology - Cell Physiology  doi:10.1152/ajpcell.00177.2021 [Abstract]

Nicotinamide N-methyltransferase in endothelium protects against oxidant stress-induced endothelial injury.,  Campagna, Roberto,Mateuszuk, Łukasz,Wojnar-Lason, Kamila,Kaczara, Patrycja,Tworzydło, Anna,Kij, Agnieszka,Bujok, Robert,Mlynarski, Jacek,Wang, Yu,Sartini, Davide,Emanuelli, Monica,Chlopicki, Stefan  (2021).  Biochimica et Biophysica Acta - Molecular Cell Research  1868 (10) :  1-14 doi:10.1016/j.bbamcr.2021.119082 [Abstract]

Impedimetric characterization of normal and cancer cell responses after nano-pulse stimulation.,  Zhang, Long,Shi, Fukun,Guo, Jinsong,Wang, Qun,Kolb, Juergen F.,Wang, Weidong,Wu, Xiaodong,Zhuang, Jie  (2021).  Journal of Physics D: Applied Physics  54 (18) :  1-9 doi:10.1088/1361-6463/abdd69 [Abstract]

Sialylated Lipooligosaccharide Contributes to Glaesserella parasuis Penetration of Porcine Respiratory Epithelial Barrier.,  Wang, Huan,Wei, Wenbin,Cao, Qi,Xu, Manman,Chen, Qichao,Lv, Yujin,Tan, Chen,Dai, Menghong,Xu, Xiaojuan,Chen, Huanchun,Wang, Xiangru  (2021).  ACS Infectious Diseases  7 (3) :  661-671 doi:10.1021/acsinfecdis.0c00850 [Abstract]

Sialic acid-modified mesoporous polydopamine induces tumor vessel normalization to enhance photodynamic therapy by inhibiting VE-cadherin internalization.,  Xu, Xiao Ling,Chen, Mei Xuan,Lou, Xue Fang,Du, Yu Yin,Shu, Gao Feng,Qi, Jing,Zhu, Meng Lu,Ying, Xiao Ying,Yu, Lian,Ji, Jian Song,Du, Yong Zhong  (2021).  Chemical Engineering Journal  414 1-13 doi:10.1016/j.cej.2021.128743 [Abstract]

Inside-out regulation of E-cadherin conformation and adhesion.,  Koirala, Ramesh,Priest, Andrew Vae,Yen, Chi-fu,Cheah, Joleen S,Pannekoek, Willem-jan,Gloerich, Martijn,Yamada, Soichiro,Sivasankar, Sanjeevi  (2021).  Proceedings of the National Academy of Sciences of the United States of America  118 (30) :  1-49 [Abstract]

ERK1/2 has divergent roles in LPS-induced microvascular endothelial cell cytokine production and permeability.,  Wong, Erika,Xu, Fenguyn,Joffre, Jérémie,Nguyen, Nina,Wilhelmsen, Kevin,Hellman, Judith  (2021).  Shock  55 (3) :  349-356 doi:10.1097/SHK.0000000000001639 [Abstract]

Endothelial SOCS3 maintains homeostasis and promotes survival in endotoxemic mice.,  Martino, Nina,Ramos, Ramon Bossardi,Lu, Shuhan,Leyden, Kara,Tomaszek, Lindsay,Sadhu, Sudeshna,Fredman, Gabrielle,Jaitovich, Ariel,Vincent, Peter A.,Adam, Alejandro P.  (2021).  JCI Insight  6 (14) :  1-21 doi:10.1172/jci.insight.147280 [Abstract]

Balanced Wnt/Dickkopf-1 signaling by mesenchymal vascular progenitor cells in the microvascular niche maintains distal lung structure and function.,  Summers, Megan E.,Richmond, Bradley W.,Kropski, Jonathan A.,Majka, Sarah A.,Bastarache, Julie A.,Hatzopoulos, Antonis K.,Bylund, Jeffery,Ghosh, Moumita,Petrache, Irina,Foronjy, Robert F.,Geraghty, Patrick,Majka, Susan M.  (2021).  American Journal of Physiology - Cell Physiology  320 (1) :  C119-C131 doi:10.1152/ajpcell.00277.2020 [Abstract]

Malondialdehyde but Not Methylglyoxal Impairs Insulin Signaling, NO Production, and Endothelial Barrier.,  Samsonov, M. V.,Podkuychenko, N. V.,Lankin, V. Z.,Vorotnikov, A. V.,Shirinsky, V. P.  (2021).  Biochemistry (Moscow) Supplement Series A: Membrane and Cell Biology  15 (2) :  195-200 doi:10.1134/S1990747821030089 [Abstract]

Brefeldin A and kifunensine modulate LPS-induced lung endothelial hyperpermeability in human and bovine cells.,  Kubra, Khadeja-Tul,Barabutis, Nektarios  (2021).  American Journal of Physiology - Cell Physiology  321 (2) :  C214-C220 doi:10.1152/ajpcell.00142.2021 [Abstract]

The Cx43 Carboxyl-Terminal Mimetic Peptide α CT1 Protects Endothelial Barrier Function in a ZO1 Binding-Competent Manner.,  Strauss, Randy E,Mezache, Louisa,Veeraraghavan, Rengasayee,Gourdie, Robert G  (2021).  Biomolecules  11 (8) :  1-20 doi:10.3390/biom11081192 [Abstract]

The SARS-CoV-2 spike protein subunit S1 induces COVID-19-like acute lung injury in Κ18-hACE2 transgenic mice and barrier dysfunction in human endothelial cells.,  Colunga Biancatelli, Ruben M. L.,Solopov, Pavel A.,Sharlow, Elizabeth R.,Lazo, John S.,Marik, Paul E.,Catravas, John D.  (2021).  American Journal of Physiology-Lung Cellular and Molecular Physiology  321 (2) :  L477-L484 doi:10.1152/ajplung.00223.2021 [Abstract]

Human milk oligosaccharides and non-digestible carbohydrates prevent adhesion of specific pathogens via modulating glycosylation or inflammatory genes in intestinal epithelial cells.,  Kong, Chunli,Beukema, Martin,Wang, Min,de Haan, Bart J.,de Vos, Paul  (2021).  Food & Function  1-20 doi:10.1039/d1fo00872b [Abstract]

Mucopolysaccharide polysulfate promotes microvascular stabilization and barrier integrity of dermal microvascular endothelial cells via activation of the angiopoietin-1/Tie2 pathway.,  Fujiwara-Sumiyoshi, Shiori,Ueda, Yuhki,Fujikawa, Mika,Osaki, Miho,Yamanaka, Naoki,Matsumoto, Tatsumi  (2021).  Journal of Dermatological Science  103 (1) :  25-32 doi:10.1016/j.jdermsci.2021.05.008 [Abstract]

SMAD6 transduces endothelial cell flow responses required for blood vessel homeostasis.,  Ruter, Dana L.,Liu, Ziqing,Ngo, Kimlynn M.,X, Shaka,Marvin, Allison,Buglak, Danielle B.,Kidder, Elise J.,Bautch, Victoria L.  (2021).  Angiogenesis  24 (2) :  387-398 doi:10.1007/s10456-021-09777-7 [Abstract]

Early administration of MPC-n(IVIg) selectively accumulates in ischemic areas to protect inflammation-induced brain damage from ischemic stroke.,  Jin, Weili,Wu, Ye,Chen, Ning,Wang, Qixue,Wang, Yunfei,Li, Yansheng,Li, Sidi,Han, Xing,Yang, Eryan,Tong, Fei,Wu, Jialing,Yuan, Xubo,Kang, Chunsheng  (2021).  Theranostics  11 (17) :  8197-8217 doi:10.7150/thno.58947 [Abstract]

Phosphorylated cingulin localises GEF-H1 at tight junctions to protect vascular barriers in blood endothelial cells.,  Holzner, Silvio,Bromberger, Sophie,Wenzina, Judith,Neumüller, Karin,Holper, Tina-Maria,Petzelbauer, Peter,Bauer, Wolfgang,Weber, Benedikt,Schossleitner, Klaudia  (2021).  Journal of Cell Science  134 (16) :  doi:10.1242/JCS.258557 [Abstract]

Ser69 phosphorylation of TIMAP affects endothelial cell migration.,  Király, Nikolett,Csortos, Csilla,Boratkó, Anita  (2021).  Experimental Lung Research  47 (6) :  doi:10.1080/01902148.2021.1960651 [Abstract]

Dephosphorylation of annexin A2 by protein phosphatase 1 regulates endothelial cell barrier.,  Király, Nikolett,Thalwieser, Zsófia,Fonódi, Márton,Csortos, Csilla,Boratkó, Anita  (2021).  IUBMB Life  73 1-12 doi:10.1002/iub.2538 [Abstract]

2′-Fucosyllactose impacts the expression of mucus-related genes in goblet cells and maintains barrier function of gut epithelial cells.,  Figueroa-Lozano, Susana,Akkerman, Renate,Beukema, Martin,van Leeuwen, Sander S.,Dijkhuizen, Lubbert,de Vos, Paul  (2021).  Journal of Functional Foods  85 1-8 doi:10.1016/j.jff.2021.104630 [Abstract]

Hsp90 inhibition protects the brain microvascular endothelium against oxidative stress.,  Uddin, Mohammad A.,Akhter, Mohammad S.,Kubra, Khadeja-Tul,Whitaker, Kathryn E.,Shipley, Summer L.,Smith, Landon M.,Barabutis, Nektarios  (2021).  Brain Disorders  1 (November 2020) :  1-6 doi:10.1016/j.dscb.2020.100001 [Abstract]

A Protective Role of FAM13A in Human Airway Epithelial Cells Upon Exposure to Cigarette Smoke Extract.,  Chen, Qing,de Vries, Maaike,Nwozor, Kingsley Okechukwu,Noordhoek, Jacobien A.,Brandsma, Corry Anke,Boezen, H. Marike,Heijink, Irene H.  (2021).  Frontiers in Physiology  12 (June) :  1-11 doi:10.3389/fphys.2021.690936 [Abstract]

Ethanol-induced lymphatic endothelial cell permeability via MAP-kinase regulation.,  Herrera, Matthew,Molina, Patricia,Souza-Smith, Flavia M.  (2021).  American Journal of Physiology - Cell Physiology  321 (1) :  C104-C116 doi:10.1152/ajpcell.00039.2021 [Abstract]

Effects of electrical fields on neuroblastoma (N2A) cell differentiation: Preliminary results.,  Fernández, Daniel Martin,García, Pablo Pérez,Martín, María E.,Daza, Paula,Serrano-Viseas, Juan Alfonso,Huertas, Gloria,Yúfera, Alberto  (2021).  BIODEVICES 2021 - 14th International Conference on Biomedical Electronics and Devices; Part of the 14th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2021  1 152-159 doi:10.5220/0010320101520159 [Abstract]

Mesenchymal stem cell carriers enhance antitumor efficacy induced by oncolytic reovirus in acute myeloid leukemia.,  Wang, Xianyao,Yang, Yichen,Wang, Nianxue,Wu, Xijun,Xu, Jianwei,Zhou, Yanhua,Zhao, Xing,He, Zhixu  (2021).  International Immunopharmacology  94 (December 2020) :  1-13 doi:10.1016/j.intimp.2021.107437 [Abstract]

Cell-free hemoglobin-mediated human lung microvascular endothelial barrier dysfunction is not mediated by cell death.,  Tomasek, Toria,Ware, Lorraine B.,Bastarache, Julie A.,Meegan, Jamie E.  (2021).  Biochemical and Biophysical Research Communications  556 199-206 doi:10.1016/j.bbrc.2021.03.161 [Abstract]

Brefeldin A and kifunensine modulate LPS-induced lung endothelial hyperpermeability in human and bovine cells.,  Kubra, Khadeja-Tul,Barabutis, Nektarios  (2021).  Molecular and Cellular Endocrinology  321 (2) :  C214-C220 doi:10.1016/j.mce.2021.111368 [Abstract]

Application of impedance measurement to investigate in vitro inhalation toxicity of bacteria.,  Klar, Stefanie,Poether, Dierk-christoph,Reinert, Jessica,Hüttig, Nicole,Linsel, Gunter,Jäckel, Udo  (2021).  Journal of Occupational Medicine and Toxicology  16 (32) :  1-10 doi:https://doi.org/10.1186/s12995-021-00317-z [Abstract]

Tumor necrosis factor-induced ArhGEF10 selectively activates RhoB contributing to human microvascular endothelial cell tight junction disruption.,  Khan, Alamzeb,Ni, Weiming,Lopez-Giraldez, Francesc,Kluger, Martin S.,Pober, Jordan S.,Pierce, Richard W.  (2021).  FASEB Journal  35 (6) :  1-13 doi:10.1096/fj.202002783RR [Abstract]

Microtubule-dependent mechanism of anti-inflammatory effect of SOCS1 in endothelial dysfunction and lung injury.,  Karki, Pratap,Cha, Boyoung,Zhang, Chen Ou,Li, Yue,Ke, Yunbo,Promnares, Kamoltip,Kaibuchi, Kozo,Yoshimura, Akihiko,Birukov, Konstantin G.,Birukova, Anna A.  (2021).  FASEB Journal  35 (4) :  1-17 doi:10.1096/fj.202001477RR [Abstract]

Involvement of N-glycans in binding of Photorhabdus luminescens Tc toxin.,  Ng'ang'a, Peter Njenga,Siukstaite, Lina,Lang, Alexander E.,Bakker, Hans,Römer, Winfried,Aktories, Klaus,Schmidt, Gudula  (2021).  Cellular Microbiology  23 (8) :  1-16 doi:10.1111/cmi.13326 [Abstract]

Acute cigarette smoke-induced eQTL affects formyl peptide receptor expression and lung function.,  Pouwels, Simon D.,Wiersma, Valerie R.,Fokkema, Immeke E.,Berg, Marijn,ten Hacken, Nick H.T.,van den Berge, Maarten,Heijink, Irene,Faiz, Alen  (2021).  Respirology  26 (3) :  233-240 doi:10.1111/resp.13960 [Abstract]

LncRNA AERRIE Is Required for Sulfatase 1 Expression, but Not for Endothelial-to-Mesenchymal Transition.,  Pham, Tan Phát,van Bergen, Anke S.,Kremer, Veerle,Glaser, Simone F.,Dimmeler, Stefanie,Boon, Reinier A.  (2021).  International Journal of Molecular Sciences  22 (15) :  1-14 doi:10.3390/ijms22158088 [Abstract]

SIKs suppress tumor function and regulate drug resistance in breast cancer.,  Xin, Ling,Liu, Chang,Liu, Yinhua,Mansel, Robert E.,Davies, Eleri,Jiang, Wen G.,Martin, Tracey A.  (2021).  American Journal of Cancer Research  11 (7) :  3537-3557 doi:10.1158/1538-7445.sabcs20-ps4-41 [Abstract]

Relative Contribution of Different Mitochondrial Oxidative Phosphorylation Components to the Retinal Pigment Epithelium Barrier Function: Implications for RPE-Related Retinal Diseases.,  Guerra, Michael H.,Yumnamcha, Thangal,Singh, Lalit P.,Ibrahim, Ahmed S.  (2021).  International Journal of Molecular Sciences  22 (15) :  8130 doi:10.3390/ijms22158130 [Abstract]

Nuclear factor of activated T-cells (NFAT) regulation of IL-1β-induced retinal vascular inflammation.,  Giblin, Meredith,Smith, Taylor E.,Winkler, Garrett,Pendergrass, Hannah A.,Kim, Minjae J.,Capozzi, Megan E.,Yang, Rong,McCollum, Gary W.,Penn, John S.  (2021).  BBA Molecular Basis of Disease  doi:10.1016/j.bbadis.2021.166238 [Abstract]

Probing tissue transglutaminase mediated vascular smooth muscle cell aging using a novel transamidation-de fi cient Tgm2 -C277S mouse model.,  Wang, Huilei,Chen, James,Jandu, Sandeep,Melucci, Sean,Savage, William,Nandakumar, Kavitha,Kang, Sara K  (2021).  Cell Death Discovery  7 (197) :  doi:10.1038/s41420-021-00543-8 [Abstract]

Group V Phospholipase A2 Mediates Endothelial Dysfunction and Acute Lung Injury Caused by Methicillin-Resistant Staphylococcus Aureus.,  Htwe, Yu Maw,Wang, Huashan,Belvitch, Patrick,Meliton, Lucille,Bandela, Mounica,Letsiou, Eleftheria,Dudek, Steven M  (2021).  Cells  10 (7) :  1731 doi:10.3390/cells10071731 [Abstract]

Distinctive Prognostic Value and Cellular Functions of Osteopontin Splice Variants in Human Gastric Cancer.,  Hao, Chengcheng,Cui, Yuxin,Lane, Jane,Jia, Shuqin,Ji, Jiafu,Jiang, Wen G  (2021).  Cells  10 (7) :  1-16 doi:10.3390/cells10071820 [Abstract]

In vitro radiotherapy and chemotherapy alter migration of brain cancer cells before cell death.,  Merrick, Michael,Mimlitz, Michael,Weeder, Catherine,Akhter, Haris,Bray, Allie,Walther, Andrew,Nwakama, Chisom,Bamesberger, Joe,Djam, Honour,Abid, Kaamil,Ekpenyong, Andrew  (2021).  Biochemistry and Biophysics Reports  27 (Sep 2021) :  101071 doi:10.1101/2020.07.23.218636 [Abstract]

Grape Seed Proanthocyanidin Extract Moderated Retinal Pigment Epithelium Cellular Senescence Through NAMPT / SIRT1 / NLRP3 Pathway.,  Wan, Wencui,Zhu, Wei,Wu, Yan,Long, Yang,Liu, Hongzhuo,Wan, Weiwei,Wan, Guangming,Yu, Jing  (2021).  Journal of Inflammation Research  14 (July) :  3129-3143 doi:10.2147/JIR.S306456 [Abstract]

Meningitic Escherichia coli α ‑ hemolysin aggravates blood – brain barrier disruption via targeting TGFβ1 ‑ triggered hedgehog signaling.,  Fu, Jiyang,Li, Liang,Huo, Dong,Yang, Ruicheng,Yang, Bo,Xu, Bojie,Yang, Xiaopei,Dai, Menghong,Tan, Chen,Chen, Huanchun,Wang, Xiangru  (2021).  Molecular Brain  14 (116) :  1-19 doi:10.1186/s13041-021-00826-2 [Abstract]

NETosis in the pathogenesis of acute lung injury following cutaneous chemical burns.,  Surolia, Ranu,Li, Fu Jun,Wang, Zheng,Kashyap, Mahendra,Srivastava, Ritesh Kumar,Traylor, Amie M.,Singh, Pooja,Dsouza, Kevin G.,Kim, Harrison,Pittet, Jean Francois,Zmijewski, Jaroslaw W.,Agarwal, Anupam,Athar, Mohammad,Ahmad, Aftab,Antony, Veena B.  (2021).  JCI Insight  6 (10) :  1-18 doi:10.1172/jci.insight.147564 [Abstract]

Controlled Release of 18-β-Glycyrrhetinic Acid from Core-Shell Nanoparticles: Effects on Cytotoxicity and Intracellular Concentration in HepG2 Cell Line.,  Nocca, Giuseppina,Avenio, Giuseppe D,Amalfitano, Adriana,Chronopoulou, Laura,Mordente, Alvaro,Palocci, Cleofe,Grigioni, Mauro  (2021).  Materials  14 (14) :  3893 doi:10.3390/ma14143893 [Abstract]

Tissue Kallikrein Exacerbating Sepsis-Induced Endothelial Hyperpermeability is Highly Predictive of Severity and Mortality in Sepsis.,  Ran, Xiao,Zhang, Qin,Li, Shaoping,Yu, Zhen,Wan, Li,Wu, Bin,Wu, Rongxue,Li, Shusheng  (2021).  Journal of Inflammation Research  14 3321-3333 doi:10.2147/JIR.S317874 [Abstract]

Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis.,  Beckmann, Denise,Römer-Hillmann, Anja,Krause, Annika,Hansen, Uwe,Wehmeyer, Corinna,Intemann, Johanna,de Gorter, David J.J.,Dankbar, Berno,Hillen, Jan,Heitzmann, Marianne,Begemann, Isabell,Galic, Milos,Weinhage, Toni,Foell, Dirk,Ai, Rizi,Kremerskothen, Joachim,Kiener, Hans P.,Müller, Sylvia,Kamradt, Thomas,Schröder, Christopher,Leitão, Elsa,Horsthemke, Bernhard,Rosenstiel, Philip,Nordström, Karl,Gasparoni, Gilles,Gasparoni, Nina,Walter, Jörn,Li, Na,Yang, Xinyi,Chung, Ho Ryun,Pavenstädt, Hermann,Lindemann, Nico,Schnittler, Hans J.,Wang, Wei,Firestein, Gary S.,Pap, Thomas,Korb-Pap, Adelheid  (2021).  Nature Communications  12 (1) :  1-17 doi:10.1038/s41467-021-23706-8 [Abstract]

SARS-CoV-2 Spike RBD-Induced Inflammatory Response by CD14+ Monocytes Causes Endothelial Barrier Dysfunction.,  Wang, Huilei,Dante, Sidartha,Nandakumar, Kavitha,Khoury, Elizabeth,Tucker, Elizabeth,Steppan, Jochen,Kannan, Sujatha,Santhanam, Lakshmi  (2021).  FASEB Journal  doi:10.1096/fasebj.2021.35.S1.03880 [Abstract]

Autocrine Effects of Brain Endothelial Cell-Produced Human Apolipoprotein E on Metabolism and Inflammation in vitro.,  Marottoli, Felecia M.,Trevino, Troy N.,Geng, Xue,Arbieva, Zarema,Kanabar, Pinal,Maienschein-Cline, Mark,Lee, James C.,Lutz, Sarah E.,Tai, Leon M.  (2021).  Frontiers in Cell and Developmental Biology  9 (June) :  1-20 doi:10.3389/fcell.2021.668296 [Abstract]

The HSP90 Inhibitor, AUY-922, Protects and Repairs Human Lung Microvascular Endothelial Cells from Hydrochloric Acid-Induced Endothelial Barrier Dysfunction.,  Colunga Biancatelli, Ruben M. L.,Solopov, Pavel,Gregory, Betsy,Catravas, John D.  (2021).  Cells  10 (6) :  1489 doi:10.3390/cells10061489 [Abstract]

Lncrsph9-4 facilitates meningitic escherichia coli-caused blood–brain barrier disruption via mir-17-5p/mmp3 axis.,  Xu, Bojie,Yang, Ruicheng,Fu, Jiyang,Yang, Bo,Chen, Jiaqi,Tan, Chen,Chen, Huanchun,Wang, Xiangru  (2021).  International Journal of Molecular Sciences  22 (12) :  doi:10.3390/ijms22126343 [Abstract]

Transendothelial Electrical Resistance Measurement across the Blood–Brain Barrier: A Critical Review of Methods.,  Vigh, Judit P.,Kincses, András,Ozgür, Burak,Walter, Fruzsina R.,Santa-Maria, Ana Raquel,Valkai, Sándor,Vastag, Mónika,Neuhaus, Winfried,Brodin, Birger,Dér, András,Deli, Mária A.  (2021).  Micromachines  12 (6) :  685 doi:10.3390/mi12060685 [Abstract]

Suppression of Endoplasmic Reticulum Stress by 4-PBA Protects Against Hyperoxia-Induced Acute Lung Injury via Up-Regulating Claudin-4 Expression.,  Pao, Hsin-Ping,Liao, Wen-I.,Tang, Shih-En,Wu, Shu-Yu,Huang, Kun-Lun,Chu, Shi-Jye  (2021).  Frontiers in Immunology  12 (May) :  1-16 doi:10.3389/fimmu.2021.674316 [Abstract]

Cell-Selective Altered Cargo Properties of Extracellular Vesicles Following In Vitro Exposures to Intermittent Hypoxia.,  Sanz-rubio, David,Khalyfa, Abdelnaby,Qiao, Zhuanhong,Ullate, Jorge,Marin, Jos M,Kheirandish-gozal, Leila,Gozal, David  (2021).  International Journal of Molecular Sciences  22 (11) :  5604 doi:10.3390/ijms22115604 [Abstract]

A protective effect of FAM13A in human bronchial epithelial cells upon exposure to cigarette smoke.,  Chen, Qing,De Vries, Maaike,Okechukwu Nwozor, Kingsley,Noordhoek, Jacobien A.,Brandsma, Corry-Anke,Boezen, Marike,Heijink, Irene  (2021).  Frontiers in Physiology  (June) :  doi:10.1183/13993003.congress-2019.pa2396 [Abstract]

Amphiregulin increases migration and proliferation of epithelial ovarian cancer cells by inducing its own expression via PI3-kinase signaling..,  Bolitho, Christine,Moscova, Michelle,Baxter, Robert C.,Marsh, Deborah J.  (2021).  Molecular and Cellular Endocrinology  104743 doi:10.1016/j.mce.2021.111338 [Abstract]

Comparison of Leading Biosensor Technologies to Detect Changes in Human Endothelial Barrier Properties in Response to Pro-Inflammatory TNFα and IL1β in Real-Time.,  Hucklesby, James J. W.,Anchan, Akshata,O'Carroll, Simon J.,Unsworth, Charles P.,Graham, Scott E.,Angel, Catherine  (2021).  Biosensors  11 (5) :  159 [Abstract]

High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages.,  Hoepel, Willianne,Chen, Hung-Jen,Geyer, Chiara E.,Allahverdiyeva, Sona,Manz, Xue D.,de Taeye, Steven W.,Aman, Jurjan,Mes, Lynn,Steenhuis, Maurice,Griffith, Guillermo R.,Bonta, Peter I.,Brouwer, Philip J.M.,Caniels, Tom G.,van der Straten, Karlijn,Golebski, Korneliusz,Jonkers, René E.,Larsen, Mads D.,Linty, Federica,Nouta, Jan,van Roomen, Cindy P.A.A.,van Baarle, Frank E.H.P.,van Drunen, Cornelis M.,Wolbink, Gertjan,Vlaar, Alexander P.J.,de Bree, Godelieve J.,Sanders, Rogier W.,Willemsen, Lisa,Neele, Annette E.,van de Beek, Diederik,Rispens, Theo,Wuhrer, Manfred,Bogaard, Harm Jan,van Gils, Marit J.,Vidarsson, Gestur,de Winther, Menno,den Dunnen, Jeroen  (2021).  Science Translational Medicine  8654 (May) :  eabf8654 doi:10.1126/scitranslmed.abf8654 [Abstract]

The individual effects of cyclin-dependent kinase inhibitors on head and neck cancer cells—a systematic analysis.,  Schoenwaelder, Nina,Salewski, Inken,Engel, Nadja,Krause, Mareike,Schneider, Björn,Müller, Michael,Riess, Christin,Lemcke, Heiko,Skorska, Anna,Grosse-Thie, Christina,Junghanss, Christian,Maletzki, Claudia  (2021).  Cancers  13 (10) :  doi:10.3390/cancers13102396 [Abstract]

Endothelial eNAMPT amplifies pre-clinical acute lung injury: efficacy of an eNAMPT-neutralising monoclonal antibody.,  Quijada, Hector,Bermudez, Tadeo,Kempf, Carrie L.,Valera, Daniel G.,Garcia, Alexander N.,Camp, Sara M.,Song, Jin H.,Franco, Evelyn,Burt, Jessica K.,Sun, Belinda,Mascarenhas, Joseph B.,Burns, Kimberlie,Gaber, Amir,Oita, Radu C.,Reyes Hernon, Vivian,Barber, Christy,Moreno-Vinasco, Liliana,Sun, Xiaoguang,Cress, Anne E.,Martin, Diego,Liu, Zhonglin,Desai, Ankit A.,Natarajan, Viswanathan,Jacobson, Jeffrey R.,Dudek, Steven M.,Bime, Christian,Sammani, Saad,Garcia, Joe G.N.  (2021).  European Respiratory Journal  57 (5) :  2002536 doi:10.1183/13993003.02536-2020 [Abstract]

Protective Role of Mytilus edulis Hydrolysate in Lipopolysaccharide-Galactosamine Acute Liver Injury.,  Starikova, Eleonora,Mammedova, Jennet,Ozhiganova, Arina,Lebedeva, Aleksandra  (2021).  Frontiers in pharmacology  12 (May) :  1-12 doi:10.3389/fphar.2021.667572 [Abstract]

PepT1-Knockout Mice Harbor a Protective Metabolome Beneficial for Intestinal Wound Healing.,  Sung, Junsik,Wang, Lixin,Long, Dingpei,Yang, Chunhua,Merlin, Didier  (2021).  American Journal of Physiology-Gastrointestinal and Liver Physiology  (March) :  doi:10.1152/ajpgi.00299.2020 [Abstract]

Downregulation of Endothelial Plexin A4 Under Inflammatory Conditions Impairs Vascular Integrity.,  Vreeken, Dianne,Bruikman, Caroline Suzanne,Stam, Wendy,Martinus, Stefan,Cox, Leonardus,Nagy, Zsófia,Zhang, Huayu,Gils, Janine Maria Van  (2021).  Frontiers in Cardiovascular Medicine  8 (May) :  1-16 doi:10.3389/fcvm.2021.633609 [Abstract]

Mitofusin-2 stabilizes adherens junctions and suppresses endothelial inflammation via modulation of β-catenin signaling.,  Kim, Young-mee,Krantz, Sarah,Jambusaria, Ankit,Toth, Peter T,Gunarathna, Isuru,Park, Gye Young,Rehman, Jalees  (2021).  Nature Communications  12 (2736) :  1-17 doi:10.1038/s41467-021-23047-6 [Abstract]

IGFBP-1 expression is reduced in human type 2 diabetic glomeruli and modulates β1-integrin/FAK signalling in human podocytes.,  Lay, Abigail C.,Hale, Lorna J.,Stowell-Connolly, Holly,Pope, Robert J.P.,Nair, Viji,Ju, Wenjun,Marquez, Eva,Rollason, Ruth,Hurcombe, Jenny A.,Hayes, Bryony,Roberts, Timothy,Gillam, Lawrence,Allington, Jonathan,Nelson, Robert G.,Kretzler, Matthias,Holly, Jeff M.P.,Perks, Claire M.,McArdle, Craig A.,Welsh, Gavin I.,Coward, Richard J.M.  (2021).  Diabetologia  doi:10.1007/s00125-021-05427-1 [Abstract]

Netrin-4 expression by human endothelial cells inhibits endothelial inflammation and senescence.,  Zhang, Huayu,Vreeken, Dianne,Leuning, Danielle G.,Bruikman, Caroline S.,Junaid, Abidemi,Stam, Wendy,de Bruin, Ruben G.,Sol, Wendy M.P.J.,Rabelink, Ton J.,van den Berg, Bernard M.,van Zonneveld, Anton Jan,van Gils, Janine M.  (2021).  International Journal of Biochemistry and Cell Biology  134 (February) :  105960 doi:10.1016/j.biocel.2021.105960 [Abstract]

Novel Curcumin-Resveratrol Solid Nanoparticles Synergistically Inhibit Proliferation of Melanoma Cells.,  Palliyage, Gayathri H.,Hussein, Noor,Mimlitz, Michael,Weeder, Catherine,Alnasser, Marya H A,Ekpenyong, Andrew,Tiwari, Amit K,Chauhan, Harsh  (2021).  Pharmaceutical Research  doi:https://doi.org/10.1007/s11095-021-03043-7 [Abstract]

Real-time monitoring the effect of cytopathic hypoxia on retinal pigment epithelial barrier functionality using electric cell-substrate impedance sensing (Ecis) biosensor technology.,  Guerra, Michael H.,Yumnamcha, Thangal,Ebrahim, Abdul Shukkur,Berger, Elizabeth A.,Singh, Lalit Pukhrambam,Ibrahim, Ahmed S.  (2021).  International Journal of Molecular Sciences  22 (9) :  doi:10.3390/ijms22094568 [Abstract]

Vitamin E analogs limit in vitro oxidant damage to bovine mammary endothelial cells.,  Kuhn, M. J.,Sordillo, L. M.  (2021).  Journal of Dairy Science  doi:10.3168/jds.2020-19675 [Abstract]

SOCS3 microtubule interaction via CLIP-170 and CLASP2 is critical for modulation of endothelial inflammation and lung injury.,  Karki, Pratap,Ke, Yunbo,Zhang, Chen Ou,Li, Yue,Tian, Yufeng,Son, Sophia,Yoshimura, Akihiko,Kaibuchi, Kozo,Birukov, Konstantin G.,Birukova, Anna A.  (2021).  Journal of Biological Chemistry  296 100239 doi:10.1074/jbc.RA120.014232 [Abstract]

Detecting effects of low levels of fccp on stem cell micromotion and wound-healing migration by time-series capacitance measurement.,  Wang, Si Han,Tung, Tse Hua,Chiu, Sheng Po,Chou, Hsin Yi,Hung, Yu Han,Lai, Yi Ting,Lee, Yu Wei,Lee, Shiao Pieng,Lo, Chun Min  (2021).  Sensors  21 (9) :  doi:10.3390/s21093017 [Abstract]

Epigenetic modulation of immune synaptic-cytoskeletal networks potentiates γδ T cell-mediated cytotoxicity in lung cancer.,  Weng, Rueyhung R.,Lu, Hsuan-Hsuan,Lin, Chien-Ting,Fan, Chia-Chi,Lin, Rong-Shan,Huang, Tai-Chung,Lin, Shu-Yung,Huang, Yi-Jhen,Juan, Yi-Hsiu,Wu, Yi-Chieh,Hung, Zheng-Ci,Liu, Chi,Lin, Xuan-Hui,Hsieh, Wan-Chen,Chiu, Tzu-Yuan,Liao, Jung-Chi,Chiu, Yen-Ling,Chen, Shih-Yu,Yu, Chong-Jen,Tsai, Hsing-Chen  (2021).  Nature Communications  12 (1) :  1-18 doi:10.1038/s41467-021-22433-4 [Abstract]

The G4 Resolvase DHX36 Possesses a Prognosis Signi fi cance and Exerts Tumour Suppressing Function Through Multiple Causal Regulations in Non-Small Cell Lung Cancer.,  Cui, Yuxin,Li, Zhilei,Cao, Junxia,Lane, Jane,Birkin, Emily,Dong, Xuefei  (2021).  Frontiers in Oncology  11 (April) :  1-16 doi:10.3389/fonc.2021.655757 [Abstract]

Dual effects of targeting S100A11 on suppressing cellular metastatic properties and sensitizing drug response in gastric cancer.,  Cui, Yuxin,Li, Liting,Li, Zhilei,Yin, Jie,Lane, Jane,Ji, Jiafu,Jiang, Wen G  (2021).  Cancer Cell International  21 (243) :  1-15 doi:10.1186/s12935-021-01949-1 [Abstract]

Modulation of The Permeability-Inducing Factor Angiopoietin-2 Through Bifonazole in Systemic Inflammation.,  Pape, Thorben,Idowu, Temitayo O,Etzrodt, Valerie,Stahl, Klaus,Seeliger, Benjamin,Haller, Hermann,David, Sascha  (2021).  Shock  doi:10.1097/SHK.0000000000001777 [Abstract]

CaMKIIδ is upregulated by pro-inflammatory cytokine IL-6 in a JAK/STAT3-dependent manner to promote angiogenesis.,  O'Brien, Brendan J,Singer, Harold A,Adam, Alejandro P,Ginnan, Roman G  (2021).  FASEB J  35 (4) :  21437 doi:10.1096/fj.202002755R [Abstract]

Influence of Fucoidan Extracts from Different Fucus Species on Adult Stem Cells and Molecular Mediators in In Vitro Models for Bone Formation and Vascularization.,  Wang, Fanlu,Xiao, Yuejun,Neupane, Sandesh,Ptak, Signe Helle,Römer, Ramona,Xiong, Junyu,Ohmes, Julia,Seekamp, Andreas,Fretté, Xavier,Alban, Susanne,Fuchs, Sabine  (2021).  Marine drugs  19 (4) :  1-22 doi:10.3390/md19040194 [Abstract]

Lasius fuliginosus Nest Carton as a Source of New Promising Bioactive Extracts with Chemopreventive Potential.,  Wagner, Grzegorz Karol,Jaszek, Magdalena,Staniec, Bernard,Prendecka, Monika,Pigo, Dominika,Belcarz, Anna,Stefaniuk, Dawid,Matuszewska, Anna,Tudruj, Ewa Pietrykowska  (2021).  International Journal of Molecular Sciences  22 (9) :  4392 doi:10.3390/ijms22094392 [Abstract]

Increase in Blood-Brain Barrier ( BBB ) Permeability Is Regulated by MMP3 via the ERK Signaling Pathway.,  Zhang, Qin,Zheng, Mei,Betancourt, Cristian E,Liu, Lifeng,Sitikov, Albert,Sladojevic, Nikola,Zhao, Qiong,Zhang, John H,Liao, James K,Wu, Rongxue  (2021).  Oxidative Medicine and Cellular Longevity  2021 doi:10.1155/2021/6655122 [Abstract]

Sipa1 is a modulator of hgf/met induced tumour metastasis via the regulation of tight junction‐based cell to cell barrier function.,  Liu, Chang,Jiang, Wen G.,Zhang, Lijian,Hargest, Rachel,Martin, Tracey A.  (2021).  Cancers  13 (7) :  1-20 doi:10.3390/cancers13071747 [Abstract]

Depletion of Arg/Abl2 improves endothelial cell adhesion and prevents vascular leak during inflammation.,  Amado-Azevedo, Joana,Stalborch, Anne-Marieke D. van,Valent, Erik T.,Nawaz, Kalim,Bezu, Jan van,Eringa, Etto C.,Hoevenaars, Femke P.M.,Cuyper, Iris M. De,Hordijk, Peter L.,Hinsbergh, Victor W.M. van,Amerongen, Geerten P. van Nieuw,Aman, Jurjan,Margadant, Coert  (2021).  Angiogenesis  Accepted for publication doi:10.1007/s10456-021-09781-x [Abstract]

Leaky Gut as a Potential Culprit for the Paradoxical Dysglycemic Response to Gastric Bypass-Associated Ileal Microbiota.,  Hankir, Mohammed K,Seyfried, Florian,Schellinger, Isabel N,Schlegel, Nicolas  (2021).  Metabolites  11 (3) :  153 doi:https://dx.doi.org/10.3390%2Fmetabo11030153 [Abstract]

Myosin phosphatase is implicated in the control of thp-1 monocyte to macrophage differentiation.,  Tóth, Emese,Erdődi, Ferenc,Kiss, Andrea  (2021).  International Journal of Molecular Sciences  22 (5) :  1-13 doi:10.3390/ijms22052516 [Abstract]

Redox-Responsive Hyaluronic Acid-Based Nanogels for the Topical Delivery of the Visual Chromophore to Retinal Photoreceptors.,  Laradji, Amine M.,Kolesnikov, Alexander V.,Karakoçak, Bedia B.,Kefalov, Vladimir J.,Ravi, Nathan  (2021).  ACS Omega  (6) :  6172-6184 doi:10.1021/acsomega.0c05535 [Abstract]

Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate.,  Lu, Tyler M,Houghton, Sean,Magdeldin, Tarig,Gabriel, José,Durán, Barcia,Minotti, Andrew P,Snead, Amanda,Sproul, Andrew,Nguyen, Duc-huy T,Xiang, Jenny,Fine, Howard A,Rosenwaks, Zev,Studer, Lorenz,Rafii, Shahin,Agalliu, Dritan,Redmond, David,Lis, Raphael  (2021).  Proceedings of the National Academy of Sciences of the United States of America  118 (8) :  doi:10.1073/pnas.2016950118 [Abstract]

Circulating exosomes and gut microbiome induced insulin resistance in mice exposed to intermittent hypoxia: Effects of physical activity.,  Khalyfa, Abdelnaby,Ericsson, Aaron,Qiao, Zhuanghong,Almendros, Isaac,Farré, Ramon,Gozal, David  (2021).  EBioMedicine  64 1-15 doi:10.1016/j.ebiom.2021.103208 [Abstract]

Intestinal Epithelial Barrier Maturation by Enteric Glial Cells is GDNF-Dependent.,  Meir, Michael,Kannapin, Felix,Diefenbacher, Markus,Ghoreishi, Yalda,Kollmann, Catherine,Flemming, Sven,Germer, Christoph-Thomas,Waschke, Jens,Leven, Patrick,Schneider, Reiner,Wehner, Sven,Burkard, Natalie,Schlegel, Nicolas  (2021).  International Journal of Molecular Sciences  22 (4) :  1887 doi:10.3390/ijms22041887 [Abstract]

The psychoactive drug of abuse mephedrone differentially disrupts blood- brain barrier properties.,  Buzhdygan, Tetyana P,Rodrigues, Cassidy R,Mcgary, Hannah M,Khan, Jana A,Andrews, Allison M,Rawls, Scott M,Ramirez, Servio H  (2021).  Journal of Neuroinflammation  18 (63) :  1-15 [Abstract]

Role of endothelial microRNA 155 on capillary leakage in systemic inflammation.,  Etzrodt, Valerie,Idowu, Temitayo O,Schenk, Heiko,Seeliger, Benjamin,Prasse, Antje,Thamm, Kristina,Pape, Thorben,Deile, Janina Müller,Meurs, Matijs Van,Thum, Thomas,Garg, Ankita,Geffers, Robert,Stahl, Klaus,Parikh, Samir M,Haller, Hermann,David, Sascha  (2021).  Critical Care  25 (76) :  1-12 doi:10.1186/s13054-021-03500-0 [Abstract]

Catecholaminergic Vasopressors Reduce Toll-Like Receptor Agonist-Induced Microvascular Endothelial Cell Permeability But Not Cytokine Production.,  Joffre, Jérémie,Lloyd, Elliot,Wong, Erika,Chung-Yeh, Che,Nguyen, Nina,Xu, Fenguyn,Legrand, Matthieu,Hellman, Judith  (2021).  Critical Care Medicine  Publish Ah 315-326 doi:10.1097/ccm.0000000000004854 [Abstract]

Bone Morphogenetic Protein-2 Induces Non-Canonical Inflammatory and Oxidative Pathways in Human Retinal Endothelial Cells.,  Al-Shabrawey, Mohamed,Hussein, Khaled,Wang, Fang,Wan, Ming,Elmasry, Khaled,Elsherbiny, Nehal,Saleh, Heba,Yu, Paul B.,Tawfik, Amany,Ibrahim, Ahmed S.  (2021).  Frontiers in Immunology  11 (January) :  1-13 doi:10.3389/fimmu.2020.568795 [Abstract]

Co-inhibition of CD73 and ADORA2B Improves Long-Term Cigarette Smoke Induced Lung Injury.,  Tian, Zhi,Dixon, Jendayi,Guo, Xiaofang,Deal, Benjamin,Liao, Qianjin,Zhou, Yujuan,Cheng, Feng,Allen-Gipson, Diane S.  (2021).  Frontiers in Physiology  12 (January) :  1-14 doi:10.3389/fphys.2021.614330 [Abstract]

Neutrophil-Derived Myeloperoxidase Facilitates Both the Induction and Elicitation Phases of Contact Hypersensitivity.,  Strzepa, Anna,Gurski, Cody J.,Dittel, Landon J.,Szczepanik, Marian,Pritchard, Kirkwood A.,Dittel, Bonnie N.  (2021).  Frontiers in Immunology  11 (January) :  1-11 doi:10.3389/fimmu.2020.608871 [Abstract]

Extended lifespan of bronchial epithelial cells maintains normal cellular phenotype and transcriptome integrity.,  O'Loughlin, Jonathan,Hall, Robert J.,Bhaker, Sangita,Portelli, Michael A.,Henry, Amanda,Pang, Vincent,Bates, David O.,Sharp, Tyson V.,Sayers, Ian  (2021).  ERJ Open Research  7 (1) :  00254-2020 doi:10.1183/23120541.00254-2020 [Abstract]

Group I p21-activated kinases in leukemia cell adhesion to fibronectin.,  Kuželová, Kateřina,Obr, Adam,Röselová, Pavla,Grebeňová, Dana,Otevřelová, Petra,Brodská, Barbora,Holoubek, Aleš  (2021).  Cell Adhesion & Migration  15 (1) :  18-36 doi:10.1080/19336918.2021.1872760 [Abstract]

Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific Pdcd10-deficient mouse model.,  Zhou, Huanjiao Jenny,Qin, Lingfeng,Jiang, Quan,Murray, Katie N.,Zhang, Haifeng,Li, Busu,Lin, Qun,Graham, Morven,Liu, Xinran,Grutzendler, Jaime,Min, Wang  (2021).  Nature Communications  12 (1) :  doi:10.1038/s41467-020-20774-0 [Abstract]

Long Non-coding RNA Aerrie Controls DNA Damage Repair via YBX1 to Maintain Endothelial Cell Function.,  Pham, Tan Phát,Bink, Diewertje I.,Stanicek, Laura,van Bergen, Anke,van Leeuwen, Esmee,Tran, Yvonne,Matic, Ljubica,Hedin, Ulf,Wittig, Ilka,Dimmeler, Stefanie,Boon, Reinier A.  (2021).  Frontiers in Cell and Developmental Biology  8 (January) :  1-16 doi:10.3389/fcell.2020.619079 [Abstract]

Astrocyte-Derived TGFβ1 Facilitates Blood–Brain Barrier Function via Non-Canonical Hedgehog Signaling in Brain Microvascular Endothelial Cells.,  Fu, Jiyang,Li, Liang,Huo, Dong,Zhi, Shuli,Yang, Ruicheng,Yang, Bo,Xu, Bojie,Zhang, Tao,Dai, Menghong,Tan, Chen,Chen, Huanchun,Wang, Xiangru  (2021).  Brain Sciences  11 (1) :  77 doi:10.3390/brainsci11010077 [Abstract]

Extending In-Plane Impedance Measurements from 2D to 3D Cultures: Design Considerations.,  De Leon, Sorel E.,Cleuren, Lana,Oo, Zay Yar,Stoddart, Paul R.,McArthur, Sally L.  (2021).  Bioengineering  8 (1) :  11 doi:10.3390/bioengineering8010011 [Abstract]

SPAK-p38 MAPK Signal Pathway Modulates Claudin-18 and Barrier Function of Alveolar Epithelium after Hyperoxic Exposure.,  Shen, Chih-hao,Lin, Jr-yu,Lu, Cheng-yo,Yang, Sung-Sen,Peng, Chung-Kan,Huang, Kun-Lun  (2021).  BMC Pulmonary Medicine  21 (58) :  1-14 doi:10.1186/s12890-021-01408-7 [Abstract]

Salinomycin suppresses TGF-β1-induced EMT by down-regulating MMP-2 and MMP-9 via the AMPK/SIRT1 pathway in non-small cell lung cancer.,  Hwang, Ki-Eun,Kim, Hyo-Jin,Song, In-Sol,Park, Chul,Jung, Jae Wan,Park, Do-Sim,Oh, Seon-Hee,Kim, Young-Suk,Kim, Hak-Ryul  (2021).  International Journal of Medical Sciences  18 (3) :  715-726 doi:10.7150/ijms.50080 [Abstract]

Activation of the mechanosensitive Ca2+ channel TRPV4 induces endothelial barrier permeability via the disruption of mitochondrial bioenergetics.,  Lu, Qing,Zemskov, Evgeny A.,Sun, Xutong,Wang, Hui,Yegambaram, Manivannan,Wu, Xiaomin,Garcia-Flores, Alejandro,Song, Shanshan,Tang, Haiyang,Kangath, Archana,Cabanillas, Gabriela Zubiate,Yuan, Jason X.J.,Wang, Ting,Fineman, Jeffrey R.,Black, Stephen M.  (2021).  Redox Biology  38 (August 2020) :  101785 doi:10.1016/j.redox.2020.101785 [Abstract]

Luminespib counteracts the Kifunensine-induced lung endothelial barrier dysfunction.,  Kubra, Khadeja Tul,Uddin, Mohammad A.,Akhter, Mohammad S.,Barabutis, Nektarios  (2020).  Current Research in Toxicology  1 111-115 doi:10.1016/j.crtox.2020.09.003 [Abstract]

Cigarette smoke and nicotine-containing electronic-cigarette vapor downregulate lung WWOX expression, which is associated with increased severity of murine acute respiratory distress syndrome.,  Zeng, Zhenguo,Chen, Weiguo,Moshensky, Alexander,Shakir, Zaid,Khan, Raheel,Crotty Alexander, Laura E.,Ware, Lorraine B.,Aldaz, C. M.,Jacobson, Jeffrey R.,Dudek, Steven M.,Natarajan, Viswanathan,Machado, Roberto F.,Singla, Sunit  (2020).  American Journal of Respiratory Cell and Molecular Biology  64 (1) :  89-99 doi:10.1165/rcmb.2020-0145OC [Abstract]

Deficiency of C-X-C chemokine receptor type 5 (CXCR5) gene causes dysfunction of retinal pigment epithelium cells.,  Lennikov, Anton,Mukwaya, Anthony,Saddala, Madhu Sudhana,Huang, Hu  (2020).  Laboratory Investigation  101 (2) :  228-244 doi:10.1038/s41374-020-00491-4 [Abstract]

ActivinA Induced SMAD1/5 Signaling in an iPSC Derived EC Model of Fibrodysplasia Ossificans Progressiva (FOP) Can Be Rescued by the Drug Candidate Saracatinib.,  Hildebrandt, Susanne,Kampfrath, Branka,Fischer, Kristin,Hildebrand, Laura,Haupt, Julia,Stachelscheid, Harald,Knaus, Petra  (2020).  Stem Cell Reviews and Reports  17 (3) :  1039-1052 doi:10.1007/s12015-020-10103-9 [Abstract]

Inhibition of Class IIa HDACs improves endothelial barrier function in endotoxin-induced acute lung injury.,  Kovacs-Kasa, Anita,Kovacs, Laszlo,Cherian-Shaw, Mary,Patel, Vijay,Meadows, Mary L.,Fulton, David J.,Su, Yunchao,Verin, Alexander D.  (2020).  Journal of Cellular Physiology  236 (4) :  1-13 doi:10.1002/jcp.30053 [Abstract]

Hemoglobin oxidation generates globin-derived peptides in atherosclerotic lesions and intraventricular hemorrhage of the brain, provoking endothelial dysfunction.,  Posta, Niké,Csősz, Éva,Oros, Melinda,Pethő, Dávid,Potor, László,Kalló, Gergő,Hendrik, Zoltán,Sikura, Katalin Éva,Méhes, Gábor,Tóth, Csaba,Posta, József,Balla, György,Balla, József  (2020).  Laboratory Investigation  100 (7) :  986-1002 doi:10.1038/s41374-020-0403-x [Abstract]

Irisin reverses intestinal epithelial barrier dysfunction during intestinal injury via binding to the integrin αVβ5 receptor.,  Bi, Jianbin,Zhang, Jia,Ren, Yifan,Du, Zhaoqing,Li, Teng,Wang, Tao,Zhang, Lin,Wang, Mengzhou,Wu, Zheng,Lv, Yi,Wu, Rongqian  (2020).  Journal of Cellular and Molecular Medicine  24 (1) :  996-1009 doi:10.1111/jcmm.14811 [Abstract]

BMX Represses Thrombin-PAR1-Mediated Endothelial Permeability and Vascular Leakage During Early Sepsis.,  Li, Zhao,Yin, Mingzhu,Zhang, Haifeng,Ni, Weiming,Pierce, Richard W.,Zhou, Huanjiao Jenny,Min, Wang  (2020).  Circulation Research  126 (4) :  471-485 doi:10.1161/CIRCRESAHA.119.315769 [Abstract]

Mesenchymal MACF1 Facilitates SMAD7 Nuclear Translocation to Drive Bone Formation.,  Zhao, Fan,Qiu, Wuxia,Wang, Pai,Zhang, Ru,Chen, Zhihao,Su, Peihong,Zhang, Yan,Li, Dijie,Yang, Chaofei,Chen, Lei,Yin, Chong,Tian, Ye,Hu, Lifang,Li, Yu,Zhang, Ge,Wu, Xiaoyang,Qian, Airong  (2020).  Cells  9 (3) :  616 doi:10.3390/cells9030616 [Abstract]

Metformin in acute respiratory distress syndrome: An opinion.,  Uddin, Mohammad A.,Akhter, Mohommad S.,Kubra, Khadeja-Tul,Siejka, Agnieszka,Barabutis, Nektarios  (2020).  Experimental Gerontology  145 (January) :  doi:10.1016/j.exger.2020.111197 [Abstract]

Biosensors for Studies on Adhesion-Mediated Cellular Responses to Their Microenvironment.,  Saffioti, Nicolás Andrés,Cavalcanti-Adam, Elisabetta Ada,Pallarola, Diego  (2020).  Frontiers in Bioengineering and Biotechnology  8 (November) :  doi:10.3389/fbioe.2020.597950 [Abstract]

Biosensors based on mechanical and electrical detection techniques.,  Chalklen, Thomas,Jing, Qingshen,Kar-Narayan, Sohini  (2020).  Sensors (Switzerland)  20 (19) :  26-37 doi:10.3390/s20195605 [Abstract]

Synergistic interactions of PlGF and VEGF contribute to blood-retinal barrier breakdown through canonical NFκB activation.,  Lennikov, Anton,Mukwaya, Anthony,Fan, Lijuan,Saddala, Madhu Sudhana,De Falco, Sandro,Huang, Hu  (2020).  Experimental Cell Research  397 (2) :  112347 doi:10.1016/j.yexcr.2020.112347 [Abstract]

miR-106b suppresses pathological retinal angiogenesis.,  Ménard, Catherine,M. Wilson, Ariel,Dejda, Agnieszka,Miloudi, Khalil,Binet, François,Crespo-Garcia, Sergio,Parinot, Célia,Pilon, Frédérique,Juneau, Rachel,MMA Andriessen, Elisabeth,Mawambo, Gaëlle,Paul SanGiovanni, John,De Guire, Vincent,Sapieha, Przemyslaw  (2020).  Aging  12 (24) :  24836-24852 doi:10.18632/aging.202404 [Abstract]

NSC348884 cytotoxicity is not mediated by inhibition of nucleophosmin oligomerization.,  Šašinková, Markéta,Heřman, Petr,Holoubek, Aleš,Strachotová, Dita,Otevřelová, Petra,Grebeňová, Dana,Kuželová, Kateřina,Brodská, Barbora  (2020).  bioRxiv  1-17 doi:10.1101/2020.02.06.936666 [Abstract]

Electrical impedance spectroscopy for monitoring chemoresistance of cancer cells.,  Crowell, Lexi L.,Yakisich, Juan S.,Aufderheide, Brian,Adams, Tayloria N.G.  (2020).  Micromachines  11 (9) :  doi:10.3390/mi11090832 [Abstract]

Identification of DHX36 as a tumour suppressor through modulating the activities of the stress-associated proteins and cyclin-dependent kinases in breast cancer.,  Zeng, Yinduo,Qin, Tao,Flamini, Valentina,Tan, Cui,Zhang, Xinke,Cong, Yizi,Birkin, Emily,Wen, G  (2020).  American Journal of Cancer Research  10 (12) :  4211-4233 [Abstract]

Differences of the tumour cell glycocalyx affect binding of capsaicin-loaded chitosan nanocapsules.,  von Palubitzki, Lydia,Wang, Yuanyuan,Hoffmann, Stefan,Vidal-y-Sy, Sabine,Zobiak, Bernd,Failla, Antonio V.,Schmage, Petra,John, Axel,Osorio-Madrazo, Anayancy,Bauer, Alexander T.,Schneider, Stefan W.,Goycoolea, Francisco M.,Gorzelanny, Christian  (2020).  Scientific Reports  10 (1) :  1-16 doi:10.1038/s41598-020-79882-y [Abstract]

Maf1 Ameliorates Sepsis-Associated Encephalopathy by Suppressing the NF- k B / NLRP3 In fl ammasome Signaling Pathway.,  Chen, Shenglong,Tang, Chaogang,Ding, Hongguang,Wang, Zhonghua  (2020).  Frontiers in Immunology  11 (December) :  1-13 doi:10.3389/fimmu.2020.594071 [Abstract]

Extratubular polymerized uromodulin induces leukocyte recruitment and inflammation in vivo.,  Immler, Roland,Lange-Sperandio, Bärbel,Steffen, Tobias,Beck, Heike,Roth, Jonas,Hupel, Georg,Pfister, Frederik,Popper, Bastian,Uhl, Bernd,Mannell, Hanna,Reichel, Christoph,Vielhauer, Volker,Scherberich, Jürgen,Sperandio, Markus,Pruenster, Monika  (2020).  Frontiers in Immunology  11 (December) :  1-16 doi:10.1101/2020.07.18.206508 [Abstract]

Vascular Tumor Recapitulated in Endothelial Cells from hiPSCs Engineered to Express the SERPINE1- ll Vascular Tumor Recapitulated in Endothelial Cells from hiPSCs Engineered to Express the SERPINE1-FOSB Translocation.,  Translocation, Fosb,Salvatori, Daniela C F,Cao, Xu,Orlova, Valeria V,Ijzendoorn, David G P Van,Salvatori, Daniela C F,Cao, Xu,Hil, Francijna Van Den,Bruijn, Inge H Briaire-de  (2020).  Cell Reports Medicine  1 (9) :  doi:10.1016/j.xcrm.2020.100153 [Abstract]

Biological properties and therapeutic effects of plant - derived nanovesicles.,  Gioia, Sante Di,Conese, Massimo  (2020).  Open Medicine  15 1096-1122 doi:https://dx.doi.org/10.1515%2Fmed-2020-0160 [Abstract]

Comparison of Leading Biosensor Technologies to Measure Endothelial Adhesion, Barrier Properties, and Responses to Cytokines in Real-Time.,  Hucklesby, James J. W.,Anchan, Akshata,O’Carroll, Simon J.,Angel, Catherine E.,Graham, E. Scott  (2020).  Proceedings  60 (1) :  62 doi:10.3390/iecb2020-07036 [Abstract]

Endothelial Barrier Integrity Is Disrupted In Vitro by Heme and by Serum From Sickle Cell Disease Patients.,  Araujo, Vanessa,Santaterra, Gomes,Marx, Maiara,Fiusa, Luz,Hounkpe, Bidossessi Wilfried,Chenou, Francine,Tonasse, Wouitchekpo Vincent,Nilkenes, Loredana,Garcia-weber, Diego,Domingos, Igor De Farias,Bezerra, Cavalcante,Andre, Marcos,Lucena-arau, Antonio Roberto,Paula, Erich Vinicius De  (2020).  Frontiers in Immunology  11 (December) :  1-10 doi:10.3389/fimmu.2020.535147 [Abstract]

Adaptation of endothelial cells to shear stress under atheroprone conditions by modulating internalization of vascular endothelial cadherin and vinculin.,  Zhong, Tingting,Li, Yanling,He, Xiaohong,Liu, Yongdong,Dong, Yugang,Ma, Hong,Zheng, Zhensheng,Zhang, Yan  (2020).  Annals of Translational Medicine  8 (21) :  1423-1423 doi:10.21037/atm-20-3426 [Abstract]

p90RSK-MAGI1 Module Controls Endothelial Permeability by Post-translational Modifications of MAGI1 and Hippo Pathway.,  Abe, Rei J.,Savage, Hannah,Imanishi, Masaki,Banerjee, Priyanka,Kotla, Sivareddy,Paez-Mayorga, Jesus,Taunton, Jack,Fujiwara, Keigi,Won, Jong Hak,Yusuf, Syed Wamique,Palaskas, Nicolas L.,Banchs, Jose,Lin, Steven H.,Schadler, Keri L.,Abe, Jun-ichi,Le, Nhat-Tu  (2020).  Frontiers in Cardiovascular Medicine  7 (November) :  1-19 doi:10.3389/fcvm.2020.542485 [Abstract]

A computer-aided design tool for biomedical OBT sensor tuning in cell-culture assays.,  Pérez, P.,Serrano, J. A.,Martín, M. E.,Daza, P.,Huertas, G.,Yúfera, A.  (2020).  Computer Methods and Programs in Biomedicine  (xxxx) :  doi:10.1016/j.cmpb.2020.105840 [Abstract]

Impedance analysis of adherent cells after in situ electroporation ‑ mediated delivery of bioactive proteins , DNA and nanoparticles in µL ‑ volumes.,  Stolwijk, Judith A,Wegener, Joachim  (2020).  Scientific Reports  1-14 doi:10.1038/s41598-020-78096-6 [Abstract]

Cardiac pericytes function as key vasoactive cells to regulate homeostasis and disease.,  Lee, Linda L,Khakoo, Aarif Y,Chintalgattu, Vishnu  (2020).  FEBS Open Bio  doi:https://doi.org/10.1002/2211-5463.13021 [Abstract]

Single-cell RNA sequencing of equine mesenchymal stromal cells from primary donor-matched tissue sources reveals functional heterogeneity in immune modulation and cell motility.,  Harman, Rebecca M,Patel, Roosheel S,Fan, Jennifer C,Park, Jee E,Rosenberg, Brad R  (2020).  Stem Cell Research & Therapy  5 (11) :  1-15 doi:https://dx.doi.org/10.1186%2Fs13287-020-02043-5 [Abstract]

Bladder cancer-derived interleukin-1 converts the vascular endothelium into a surface.,  John, A,Günes, C,Bolenz, C,Bauer, A T,Schneider, S W,Gorzelanny, C  (2020).  BMC cancer  20 (1178) :  1-13 doi:https://dx.doi.org/10.1186%2Fs12885-020-07548-z [Abstract]

CYR61 synthesis is Induced by Interleukin-6 and Promotes Migration and Invasion of Fibroblast-like Synoviocytes in Rheumatoid Arthritis.,  Choi, Changmin,Jeong, Wooseong,Ghang, Byeongzu,Park, Yonggeun,Cho, Moonjae,Kim, Jinseok  (2020).  Arthritis Res Ther  22 1-13 doi:https://dx.doi.org/10.1186%2Fs13075-020-02369-8 [Abstract]

Dysregulated Host Responses Underlie 2009 Pandemic Influenza-Methicillin Resistant Staphylococcus aureus Coinfection Pathogenesis at the Alveolar-Capillary Barrier.,  Nickol, Michaela E.,Lyle, Sarah M.,Dennehy, Brendan,Kindrachuk, Jason  (2020).  Cells  9 (11) :  2472 doi:https://dx.doi.org/10.3390%2Fcells9112472 [Abstract]

Alzheimer’s amyloid β heterogeneous species differentially affect brain endothelial cell viability, blood‐brain barrier integrity, and angiogenesis.,  Parodi‐Rullán, Rebecca,Ghiso, Jorge,Cabrera, Erwin,Rostagno, Agueda,Fossati, Silvia  (2020).  Aging Cell  (July) :  1-15 doi:10.1111/acel.13258 [Abstract]

Drug Crystal-Related Gastrointestinal Complications Involve Crystal-Induced Release of Neutrophil and Monocyte Extracellular Traps.,  Kim, Tehyung,de Oliveira Silva Lautenschlager, Sueli,Ma, Qiuyue,Eller, Kathrin,Pollheimer, Marion Julia,Lazarin-Bidóia, Danielle,Nakamura, Celso Vataru,Anders, Hans Joachim,Steiger, Stefanie  (2020).  Cells  9 (11) :  1-18 doi:10.3390/cells9112481 [Abstract]

Microembolus clearance through angiophagy is an auxiliary mechanism preserving tissue perfusion in the rat brain.,  van der Wijk, Anne Eva,Georgakopoulou, Theodosia,Majolée, Jisca,van Bezu, Jan S.M.,van der Stoel, Miesje M.,van het Hof, Bert J.,de Vries, Helga E.,Huveneers, Stephan,Hordijk, Peter L.,Bakker, Erik N.T.P.,van Bavel, Ed  (2020).  Acta Neuropathologica Communications  8 (1) :  1-14 doi:10.1186/s40478-020-01071-9 [Abstract]

Analysis of Melanoma Secretome for Factors That Directly Disrupt the Barrier Integrity of Brain Endothelial Cells.,  Anchan, Akshata,Martin, Olivia,Hucklesby, James J. W.,Finlay, Graeme,Johnson, Rebecca H.,Robilliard, Laverne D.,O’Carroll, Simon J.,Angel, Catherine E.,Graham, E Scott  (2020).  International Journal of Molecular Sciences  21 (21) :  8193 doi:10.3390/ijms21218193 [Abstract]

RAC1 nitration at Y32 IS involved in the endothelial barrier disruption associated with lipopolysaccharide-mediated acute lung injury.,  Wang, Ting,Yegambaram, Manivannan,Gross, Christine,Sun, Xutong,Lu, Qing,Wang, Hui,Wu, Xiaomin,Kangath, Archana,Tang, Haiyang,Aggarwal, Saurabh,Black, Stephen M.  (2020).  Redox Biology  doi:https://dx.doi.org/10.1016%2Fj.redox.2020.101794 [Abstract]

Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure.,  Michalick, Laura,Weidenfeld, Sarah,Grimmer, Benjamin,Fatykhova, Diana,Daniel, Philip,Behrens, Felix,Dohmen, Melanie,Brack, Markus C,Schulz, Sabrina,Simmons, Szandor,Müller-redetzky, Holger,Suttorp, Norbert,Kurth, Florian,Neudecker, Jens,Toennies, Mario,Bauer, Torsten T.,Eggeling, Stephan,Corman, Victor Max,Hocke, Andreas C.,Witzenrath, Martin,Hippenstiel, Stefan,Kuebler, Wolfgang M.  (2020).  European Respiratory Journal  doi:https://dx.doi.org/10.1183%2F13993003.02384-2020 [Abstract]

Involvement of the unfolded protein response in the protective effects of growth hormone releasing hormone antagonists in the lungs.,  Akhter, Mohammad S,Uddin, Mohammad A,Schally, Andrew V,Tul, Khadeja,Nektarios, Kubra  (2020).  Journal of Cell Communication and Signaling  (0123456789) :  3-7 doi:10.1007/s12079-020-00593-0 [Abstract]

TRPV4 channels are essential for alveolar epithelial barrier function as protection from lung edema.,  Weber, Jonas,Rajan, Suhasini,Schremmer, Christian,Chao, Yu-Kai,Krasteva-Christ, Gabriela,Kannler, Martina,Yildirim, Ali Önder,Brosien, Monika,Schredelseker, Johann,Weissmann, Norbert,Grimm, Christian,Gudermann, Thomas,Dietrich, Alexander  (2020).  JCI Insight  5 (20) :  1-16 doi:10.1172/jci.insight.134464 [Abstract]

Circ_2858 helps blood-brain barrier disruption by increasing VEGFA via sponging miR-93-5p during Escherichia coli meningitis.,  Yang, Ruicheng,Chen, Jiaqi,Xu, Bojie,Yang, Bo,Fu, Jiyang,Xiao, Siyu,Tan, Chen,Chen, Huanchun,Wang, Xiangru  (2020).  Molecular Therapy - Nucleic Acids  22 (December) :  708-721 doi:10.1016/j.omtn.2020.09.034 [Abstract]

Indoxylsulfate, a metabolite of the microbiome, has cytostatic effects in breast cancer via activation of ahr and pxr receptors and induction of oxidative stress.,  Sári, Zsanett,Mikó, Edit,Kovács, Tünde,Boratkó, Anita,Ujlaki, Gyula,Jankó, Laura,Kiss, Borbála,Uray, Karen,Bai, Péter  (2020).  Cancers  12 (10) :  1-23 doi:10.3390/cancers12102915 [Abstract]

Protein disulphide isomerase a1 is involved in the regulation of breast cancer cell adhesion and transmigration via lung microvascular endothelial cells.,  Stojak, Marta,Milczarek, Magdalena,Kurpinska, Anna,Suraj-Prazmowska, Joanna,Kaczara, Patrycja,Wojnar-Lason, Kamila,Banach, Joanna,Stachowicz-Suhs, Martyna,Rossowska, Joanna,Kalviņš, Ivars,Wietrzyk, Joanna,Chlopicki, Stefan  (2020).  Cancers  12 (10) :  1-22 doi:10.3390/cancers12102850 [Abstract]

Epac1 Is Crucial for Maintenance of Endothelial Barrier Function through A Mechanism Partly Independent of Rac1.,  García-Ponce, Alexander,Schuster, Katharina,Døskeland, Stein Ove,Reed, Rolf K.,Curry, Fitz Roy E.,Waschke, Jens,Radeva, Mariya Y.  (2020).  Cells  9 (10) :  1-20 doi:10.3390/cells9102170 [Abstract]

The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models.,  Klems, Alina,van Rijssel, Jos,Ramms, Anne S,Wild, Raphael,Hammer, Julia,Merkel, Melanie,Derenbach, Laura,Préau, Laetitia,Hinkel, Rabea,Suarez-Martinez, Irina,Schulte-Merker, Stefan,Vidal, Ramon,Sauer, Sascha,Kivelä, Riikka,Alitalo, Kari,Kupatt, Christian,van Buul, Jaap D,le Noble, Ferdinand  (2020).  Nature Communications  11 (1) :  5319 doi:10.1038/s41467-020-19008-0 [Abstract]

Bardoxolone Methyl Displays Detrimental Effects on Endothelial Bioenergetics, Suppresses Endothelial ET-1 Release, and Increases Endothelial Permeability in Human Microvascular Endothelium.,  Szczesny-Malysiak, Ewa,Stojak, Marta,Campagna, Roberto,Grosicki, Marek,Jamrozik, Marek,Kaczara, Patrycja,Chlopicki, Stefan  (2020).  Oxidative Medicine and Cellular Longevity  2020 1-16 doi:10.1155/2020/4678252 [Abstract]

Cigarette Smoke and Nicotine-Containing E-cigarette Vapor Downregulate Lung WWOX Expression Which is Associated with Increased Severity of Murine ARDS.,  Zheng, Zhenguo,Chen, Weiguo,Moshensky, Alexander,Shakir, Zaid,Khan, Raheel,Crotty Alexander, Laura E.,Ware, Lorraine B,Aldaz, C M,Jacobson, Jeffrey R.,Dudek, Steven M.,Natarajan, Viswanathan,Machado, Roberto F.,Singla, Sunit  (2020).  Am J Respir Cell Mol Biol.  doi:https://doi.org/10.1165/rcmb.2020-0145oc [Abstract]

Indolepropionic acid, a metabolite of the microbiome, has cytostatic properties in breast cancer by activating ahr and pxr receptors and inducing oxidative stress.,  Sári, Zsanett,Mikó, Edit,Kovács, Tünde,Jankó, Laura,Csonka, Tamás,Lente, Gréta,Sebő, Éva,Tóth, Judit,Tóth, Dezső,Árkosy, Péter,Boratkó, Anita,Ujlaki, Gyula,Török, Miklós,Kovács, Ilona,Szabó, Judit,Kiss, Borbála,Méhes, Gábor,Goedert, James J.,Bai, Péter  (2020).  Cancers  12 (9) :  1-27 doi:10.3390/cancers12092411 [Abstract]

Distinct Factors Secreted by Adipose Stromal Cells Protect the Endothelium From Barrier Dysfunction and Apoptosis.,  Lu, Hongyan,Merfeld-Clauss, Stephanie,Jawed, Yameena,March, Keith L.,Coleman, Michael E.,Bogatcheva, Natalia V.  (2020).  Frontiers in Cell and Developmental Biology  8 (September) :  1-15 doi:10.3389/fcell.2020.584653 [Abstract]

Exacerbated inflammatory signaling underlies aberrant response to BMP9 in pulmonary arterial hypertension lung endothelial cells.,  Szulcek, Robert,Sanchez-Duffhues, Gonzalo,Rol, Nina,Pan, Xiaoke,Tsonaka, Roula,Dickhoff, Chris,Yung, Lai Ming,Manz, Xue D.,Kurakula, Kondababu,Kiełbasa, Szymon M.,Mei, Hailiang,Timens, Wim,Yu, Paul B.,Bogaard, Harm Jan,Goumans, Marie José  (2020).  Angiogenesis  23 (4) :  699-714 doi:10.1007/s10456-020-09741-x [Abstract]

The SARSCoV2 spike protein alters barrier function in 2D static and 3D microfluidic in vitro models of the human blood–brain barrier.,  Buzhdygan, Tetyana P,DeOre, Brandon J,Baldwin-Leclair, Abigail,McGary, Hannah,Razmpour, Roshanak,Galie, Peter A,Potula, Raghava,Andrews, Allison M,Ramirez, Servio Heybert  (2020).  bioRxiv  146 (September) :  2020.06.15.150912 doi:10.1016/j.nbd.2020.105131 [Abstract]

Tim-3 promotes tube formation and decreases tight junction formation in vascular endothelial cells.,  Cong, Yizi,Wang, Xingmiao,Wang, Suxia,Qiao, Guangdong,Li, Yalun,Cao, Jianqiao,Jiang, Wenguo,Cui, Yuxin  (2020).  Bioscience Reports  40 (10) :  doi:https://dx.doi.org/10.1042%2FBSR20202130 [Abstract]

Extracellular vesicles released from p18 overexpressing pulmonary endothelial cells are barrier protective – potential implications for acute respiratory distress syndrome.,  Harrington, Elizabeth O.,Braza, Julie,Shil, Aparna,Chichger, Havovi  (2020).  Pulmonary Circulation  10 (3) :  doi:10.1177/2045894020951759 [Abstract]

G Protein-Coupled Receptors in the Mammalian Blood-Brain Barrier.,  Pluimer, Brock R.,Colt, Mark,Zhao, Zhen  (2020).  Frontiers in Cellular Neuroscience  14 (June) :  1-9 doi:10.3389/fncel.2020.00139 [Abstract]

Pathophysiology of Aortic Aneurysms: Insights from Animal Studies.,  Khoury, Mitri K,Stranz, Amelia R,Liu, Bo  (2020).  Cardiol Cardiovasc Med.  4 (4) :  498-514 doi:10.26502/fccm.92920146.Pathophysiology [Abstract]

State-of-Art Bio-Assay Systems and Electrochemical Approaches for Nanotoxicity Assessment.,  Shinde, Ravikumar B.,Veerapandian, Murugan,Kaushik, Ajeet,Manickam, Pandiaraj  (2020).  Frontiers in Bioengineering and Biotechnology  8 (April) :  doi:10.3389/fbioe.2020.00325 [Abstract]

SIRT7 deficiency suppresses inflammation, induces EndoMT, and increases vascular permeability in primary pulmonary endothelial cells.,  Wyman, Anne E.,Nguyen, Trang T.T.,Karki, Pratap,Tulapurkar, Mohan E.,Zhang, Chen Ou,Kim, Junghyun,Feng, Theresa G.,Dabo, Abdoulaye J.,Todd, Nevins W.,Luzina, Irina G.,Geraghty, Patrick,Foronjy, Robert F.,Hasday, Jeffrey D.,Birukova, Anna A.,Atamas, Sergei P.,Birukov, Konstantin G.  (2020).  Scientific Reports  10 (1) :  1-17 doi:10.1038/s41598-020-69236-z [Abstract]

miR-96 and miR-183 differentially regulate neonatal and adult postinfarct neovascularization.,  Castellan, Raphael F.P.,Vitiello, Milena,Vidmar, Martina,Johnstone, Steven,Iacobazzi, Dominga,Mellis, David,Cathcart, Benjamin,Thomson, Adrian,Ruhrberg, Christiana,Caputo, Massimo,Newby, David E.,Gray, Gillian A.,Baker, Andrew H.,Caporali, Andrea,Meloni, Marco  (2020).  JCI Insight  5 (14) :  1-14 doi:10.1172/JCI.INSIGHT.134888 [Abstract]

Specialized differentially pro-resolving altered in peripheral lipid mediators blood of are patients with multiple sclerosis and attenuate monocyte and blood-brain barrier dysfunction.,  Kooij, Gijs,Troletti, Claudio Derada,Leuti, Alessandro,Norris, Paul C.,Riley, Ian,Albanese, Maria,Ruggieri, Serena,Libreros, Stephania,van der Pol, Susanne M.A.,van het Hof, Bert,Schell, Yoëlle,Guerrera, Gisella,Buttari, Fabio,Mercuri, Nicola Biagio,Centonze, Diego,Gasperini, Claudio,Battistini, Luca,de Vries, Helga E.,Serhan, Charles N.,Chiurchiù, Valerio  (2020).  Haematologica  105 (8) :  2056-2070 doi:10.3324/haematol.2019.219519 [Abstract]

Extracellular vesicle transfer from endothelial cells drives ve-cadherin expression in breast cancer cells, thereby causing heterotypic cell contacts.,  Rezaei, Maryam,Martins Cavaco, Ana C.,Stehling, Martin,Nottebaum, Astrid,Brockhaus, Katrin,Caliandro, Michele F.,Schelhaas, Sonja,Schmalbein, Felix,Vestweber, Dietmar,Eble, Johannes A.  (2020).  Cancers  12 (8) :  1-25 doi:10.3390/cancers12082138 [Abstract]

Identification of specific tie2 cleavage sites and therapeutic modulation in experimental sepsis.,  Idowu, Temitayo O.,Etzrodt, Valerie,Seeliger, Benjamin,Bolanos-Palmieri, Patricia,Thamm, Kristina,Haller, Hermann,David, Sascha  (2020).  eLife  9 1-15 doi:10.7554/ELIFE.59520 [Abstract]

Δ9-Tetrahydrocannabinol Prevents Mortality from Acute Respiratory Distress Syndrome through the Induction of Apoptosis in Immune Cells, Leading to Cytokine Storm Suppression.,  Mohammed, Amira,F K Alghetaa, Hasan,Miranda, Kathryn,Wilson, Kiesha,P Singh, Narendra,Cai, Guoshuai,Putluri, Nagireddy,Nagarkatti, Prakash,Nagarkatti, Mitzi  (2020).  International journal of molecular sciences  21 (17) :  doi:10.3390/ijms21176244 [Abstract]

Site-specific opening of the blood-brain barrier by extracellular histones.,  Villalba, Nuria,Baby, Sheon,Cha, Byeong J.,Yuan, Sarah Y.  (2020).  Journal of neuroinflammation  17 (1) :  281 doi:10.1186/s12974-020-01950-x [Abstract]

Gut Ischemia Reperfusion Injury Induces Lung Inflammation via Mesenteric Lymph-Mediated Neutrophil Activation.,  Ma, Yonggang,Zabell, Taylor,Creasy, Alexandra,Yang, Xiaoyuan,Chatterjee, Victor,Villalba, Nuria,Kistler, Erik B.,Wu, Mack H.,Yuan, Sarah Y.  (2020).  Frontiers in Immunology  11 (September) :  1-12 doi:10.3389/fimmu.2020.586685 [Abstract]

Let-7G Counteracts Endothelial Dysfunction and Ameliorating Neurological Functions in Mouse Ischemia/Reperfusion Stroke Model.,  Bernstein, David L.,Gajghate, Sachin,Reichenbach, Nancy L.,Winfield, Malika,Persidsky, Yuri,Heldt, Nathan A.,Rom, Slava  (2020).  Brain, Behavior, and Immunity  87 (October 2019) :  543-555 doi:10.1016/j.bbi.2020.01.026 [Abstract]

Targeting NOX4 alleviates sepsis-induced acute lung injury via attenuation of redox-sensitive activation of CaMKII/ERK1/2/MLCK and endothelial cell barrier dysfunction.,  Jiang, Jinyao,Huang, Kai,Xu, Shiqing,Garcia, Joe G.N.,Wang, Chen,Cai, Hua  (2020).  Redox Biology  36 101638 doi:10.1016/j.redox.2020.101638 [Abstract]

Impedance Spectroscopy as a Tool for Monitoring Performance in 3D Models of Epithelial Tissues.,  Gerasimenko, Tatiana,Nikulin, Sergey,Zakharova, Galina,Poloznikov, Andrey,Petrov, Vladimir,Baranova, Ancha,Tonevitsky, Alexander  (2020).  Frontiers in Bioengineering and Biotechnology  7 (January) :  doi:10.3389/fbioe.2019.00474 [Abstract]

Novel ginsenoside derivative 20(S)-Rh2E2 suppresses tumor growth and metastasis in vivo and in vitro via intervention of cancer cell energy metabolism.,  Huang, Qi,Zhang, Hui,Bai, Li Ping,Law, Betty Yuen Kwan,Xiong, Haoming,Zhou, Xiaobo,Xiao, Riping,Qu, Yuan Qing,Mok, Simon Wing Fai,Liu, Liang,Wong, Vincent Kam Wai  (2020).  Cell Death and Disease  11 (8) :  doi:10.1038/s41419-020-02881-4 [Abstract]

Potential antitumor activity of digitoxin and user-designed analog administered to human lung cancer cells.,  Eldawud, Reem,Wagner, Alixandra,Dong, Chenbo,Gupta, Neha,Rojanasakul, Yon,O'Doherty, George,Stueckle, Todd A.,Dinu, Cerasela Zoica  (2020).  Biochimica et Biophysica Acta - General Subjects  1864 (11) :  129683 doi:10.1016/j.bbagen.2020.129683 [Abstract]

Resident mesenchymal vascular progenitors modulate adaptive angiogenesis and pulmonary remodeling via regulation of canonical Wnt signaling.,  Summers, Megan E.,Richmond, Bradley W.,Menon, Swapna,Sheridan, Ryan M.,Kropski, Jonathan A.,Majka, Sarah A.,Taketo, M. Mark,Bastarache, Julie A.,West, James D.,De Langhe, Stijn,Geraghty, Patrick,Klemm, Dwight J.,Chu, Hong Wei,Friedman, Rachel S.,Tao, Yuankai K.,Foronjy, Robert F.,Majka, Susan M.  (2020).  FASEB Journal  34 (8) :  10267-10285 doi:10.1096/fj.202000629R [Abstract]

The Current Trends of Biosensors in Tissue Engineering.,  Li, Yi Chen Ethan,Lee, I. Chi  (2020).  Biosensors  10 (8) :  doi:10.3390/bios10080088 [Abstract]

Fasudil loaded PLGA microspheres as potential intravitreal depot formulation for glaucoma therapy.,  Mietzner, Raphael,Kade, Christian,Froemel, Franziska,Pauly, Diana,Stamer, W. Daniel,Ohlmann, Andreas,Wegener, Joachim,Fuchshofer, Rudolf,Breunig, Miriam  (2020).  Pharmaceutics  12 (8) :  1-22 doi:10.3390/pharmaceutics12080706 [Abstract]

Measuring Cell Growth and Junction Development in Epithelial Cells Using Electric Cell-Substrate Impedance Sensing (ECIS).,  Anwer, Shaista,Szaszi, Katalin  (2020).  bio-protocol  10 (16) :  doi:https://doi.org/10.21769/BioProtoc.3729 [Abstract]

Correlation of host inflammatory cytokines and immune-related metabolites , but not viral NS1 protein , with disease severity of dengue virus infection.,  Soe, Hui Jen,Manikam, Rishya,Raju, Chandramathi Samudi,Khan, Mohammad Asif,Devi, Shamala,Id, Sekaran  (2020).  PloS one  15 (8) :  doi:10.1371/journal.pone.0237141 [Abstract]

Identification of a combination of transcription factors that synergistically increases endothelial cell barrier resistance.,  Roudnicky, Filip,Kim, Bo Kyoung,Lan, Yanjun,Schmucki, Roland,Küppers, Verena,Christensen, Klaus,Graf, Martin,Patsch, Christoph,Burcin, Mark,Meyer, Claas Aiko,Westenskow, Peter D.,Cowan, Chad A.  (2020).  Scientific Reports  10 (1) :  1-9 doi:10.1038/s41598-020-60688-x [Abstract]

The MARCH6-SQLE Axis Controls Endothelial Cholesterol Homeostasis and Angiogenic Sprouting.,  Tan, Josephine Mathilde Elisabeth,van der Stoel, Miesje Maxime,van den Berg, Marlene,van Loon, Nienke Marlies,Moeton, Martina,Scholl, Edwin,van der Wel, Nicole Neeltje,Kovačević, Igor,Hordijk, Peter Lodewijk,Loregger, Anke,Huveneers, Stephan,Zelcer, Noam  (2020).  Cell Reports  32 (5) :  doi:10.1016/j.celrep.2020.107944 [Abstract]

Investigation of Normal Cell and Cancer Cell Attachment and the Effects of Ganoderma Lucidum Using an Electric Impedance Sensing Technique.,  Shi Qing Kong, Steffi,Martinez, Alejandra,Behravan, Maddy  (2020).  MRS Advances  doi:https://doi.org/10.1557/adv.2020.313 [Abstract]

Bone Morphogenetic Protein ( BMP ) 4 But Not BMP2 Disrupts the Barrier Integrity of Retinal Pigment Epithelia and Induces Their Migration : A Potential Role in Neovascular Age-Related Macular Degeneration.,  Ibrahim, Ahmed S,Hussein, Khaled,Wang, Fang,Wan, Ming,Saad, Nancy,Essa, Maamon,Kim, Ivana,Shakoor, Akbar,Owen, Leah A,DeAngelis, Margaret M,Al-Shabrawey, Mohamed  (2020).  Journal of Clinical Medicine  9 (7) :  doi:https://doi.org/10.3390/jcm9072293 [Abstract]

An in vitro model of chronic wounding and its implication for age-related macular degeneration.,  Id, Lindsay J Bailey-steinitz,Shih, Ying-hsuan,Radeke, Monte J,Coffey, Pete J  (2020).  PLOS ONE  1-22 doi:10.1371/journal.pone.0236298 [Abstract]

Discovery of novel L-type voltage-gated calcium channel blockers and application for the prevention of inflammation and angiogenesis.,  Saddala, Madhu Sudhana,Lennikov, Anton,Mukwaya, Anthony,Yang, Yan,Hill, Michael A.,Lagali, Neil,Huang, Hu  (2020).  Journal of Neuroinflammation  17 (1) :  1-23 doi:10.1186/s12974-020-01801-9 [Abstract]

IGSF3 Mutation Identified in Patient With Severe COPD Alters Cell Function and Motility.,  Schweitzer, Kelly S,Jinawath, Natini,Yonescu, Raluca,Ni, Kevin,Rush, Natalia,Charoensawan, Varodom,Bronova, Irina,Berdyshev, Evgeny,Leach, Sonia M,Gillenwater, Lucas A,Bowler, Russell P,Pearse, David B,Griffin, Constance A,Petrache, Irina  (2020).  JCI Insight  doi:10.1172/jci.insight.138101 [Abstract]

In vitro endothelial hyperpermeability occurs early following traumatic hemorrhagic shock.,  van Leeuwen, Anoek LI,Naumann, David N,Dekker, Nicole AM,Hordijk, Peter L,Hutchings, Sam D,Boer, Christa,van den Brom, Charissa E  (2020).  Clinical Hemorheology and Microcirculation  1-13 doi:10.3233/CH-190642 [Abstract]

Combination of HIV-1 and Diabetes Enhances Blood Brain Barrier Injury via Effects on Brain Endothelium and Pericytes.,  Rom, Slava,Gajghate, Sachin,Winfield, Malika,Reichenbach, Nancy L,Persidsky, Yuri  (2020).  International Journal of Molecular Sciences  21 (13) :  4663 doi:https://doi.org/10.3390/ijms21134663 [Abstract]

Using Electric Cell-Substrate Impedance Sensing (ECIS) as a novel method to evaluate bacterial urinary tract infections.,  Horseman, Tim,Campbell, Carmen,Gomes, Grace,Fong, Keith  (2020).  The Journal of Immunology  204 (1 Supplement) :  [Abstract]

Using Electric Cell-substrate Impedance Sensing to Characterize Effects of Curcumin on NRK Cells.,  Troy, Erin,Beahm, Derek  (2020).  Biophysical journal  118 (3) :  doi:https://doi.org/10.1016/j.bpj.2019.11.1782 [Abstract]

Assessment of cytotoxicity of magnesium oxide and magnesium hydroxide nanoparticles using the electric cell-substrate impedance sensing.,  Pallavi, Manishi,Waterman, Jenora,Koo, Youngmi,Sankar, Jagannathan,Yun, Yeoheung  (2020).  Applied Sciences (Switzerland)  10 (6) :  doi:10.3390/app10062114 [Abstract]

Cartilage acidic protein 1 promotes increased cell viability, cell proliferation and energy metabolism in primary human dermal fibroblasts.,  Letsiou, Sophia,Félix, Rute C.,Cardoso, João C.R.,Anjos, Liliana,Mestre, Ana L.,Gomes, Henrique L.,Power, Deborah M.  (2020).  Biochimie  171-172 72-78 doi:10.1016/j.biochi.2020.02.008 [Abstract]

The identification and function of a Netrin-1 mutation in a pedigree with premature atherosclerosis.,  Bruikman, Caroline S.,Vreeken, Dianne,Zhang, Huayu,van Gils, Marit J.,Peter, Jorge,van Zonneveld, Anton Jan,Hovingh, G. Kees,van Gils, Janine M.  (2020).  Atherosclerosis  301 (December 2019) :  84-92 doi:10.1016/j.atherosclerosis.2020.02.015 [Abstract]

Zika virus dysregulates human Sertoli cell proteins involved in spermatogenesis with little effect on tight junctions.,  Rashid, Mahamud-ur,Zahedi-amiri, Ali,Glover, Kathleen K M,Gao, Ang,Nickol, E,Kindrachuk, Jason,Wilkins, John A,Coombs, Kevin M.  (2020).  PLoS neglected tropical diseases  14 (6) :  1-23 doi:10.1371/journal.pntd.0008335 [Abstract]

Endothelial semaphorin 3F maintains endothelial barrier function and inhibits monocyte migration.,  Zhang, Huayu,Vreeken, Dianne,Junaid, Abidemi,Wang, Gangqi,Sol, Wendy M.P.J.,de Bruin, Ruben G.,van Zonneveld, Anton Jan,van Gils, Janine M.  (2020).  International Journal of Molecular Sciences  21 (4) :  doi:10.3390/ijms21041471 [Abstract]

Use of Discrete Wavelet Transform to Assess Impedance Fluctuations Obtained From Cellular Micromotion.,  Tung, Tse-Hua,Wang, Si-Han,Huang, Chun-Chung,Su, Tai-Yuan,Lo, Chun-Min  (2020).  Sensors  20 (11) :  doi:https://doi.org/10.3390/s20113250 [Abstract]

Functional and Cell Surface Characteristics of Periodontal Ligament Cells (PDLCs) on RGD-synthetic Polypeptide Conjugate Coatings.,  Khorolsuren, Zambaga,Lang, Orsolya,Pallinger, Eva,Foldes, Anna,Szabolcs, Gyulai-Gaal,Varga, Gabor,Mezo, Gabor,Vag, Janos,Kohidai, Laszlo  (2020).  J Periodontal Research  doi:https://doi.org/10.1111/jre.12760 [Abstract]

Cytoplasm-localized SIRT1 downregulation attenuates apoptosis and cell cycle arrest in cisplatin-resistant lung cancer A549 cells.,  Yu, Hyeran,Kim, Young Mee,Cho, Moonjae  (2020).  Journal of Cancer  11 (15) :  4495-4509 doi:10.7150/jca.44383 [Abstract]

Hyperglycemia and advanced glycation end products disrupt BBB and promote occludin and claudin-5 protein secretion on extracellular microvesicles.,  Rom, Slava,Heldt, Nathan A.,Gajghate, Sachin,Seliga, Alecia,Reichenbach, Nancy L.,Persidsky, Yuri  (2020).  Scientific Reports  10 (1) :  1-14 doi:10.1038/s41598-020-64349-x [Abstract]

Sphingosine-1-phosphate receptor-independent lung endothelial cell barrier disruption induced by FTY720 regioisomers.,  Camp, Sara M.,Marciniak, Alexander,Chiang, Eddie T.,Garcia, Alexander N.,Bittman, Robert,Polt, Robin,Perez, Ruth G.,Dudek, Steven M.,Garcia, Joe G.N.  (2020).  Pulmonary Circulation  10 (1) :  doi:10.1177/2045894020905521 [Abstract]

Transcriptomics analysis of pericytes from retinas of diabetic animals reveals novel genes and molecular pathways relevant to blood-retinal barrier alterations in diabetic retinopathy.,  Rangasamy, Sampathkumar,Monickaraj, Finny,Legendre, Christophe,Cabrera, Andrea P.,Llaci, Lorida,Bilagody, Cherae,McGuire, Paul,Das, Arup  (2020).  Experimental Eye Research  195 (March) :  108043 doi:10.1016/j.exer.2020.108043 [Abstract]

Focal adhesion kinase and Src mediate microvascular hyperpermeability caused by fibrinogen- γC- terminal fragments.,  Guo, Xiaohua,Eitnier, Rebecca A.,Beard, Richard S.,Meegan, Jamie E.,Yang, Xiaoyuan,Aponte, Alexandra M.,Wang, Fang,Nelson, Peter R.,Wu, Mack H.  (2020).  PloS one  15 (4) :  e0231739 doi:10.1371/journal.pone.0231739 [Abstract]

Electrochemical Assessment of Anticancer Compounds on the Human Tongue Squamous.,  Huang, Chun-Chung,Tung, Tse-Hua,Huang, Chien-Chu,Lin, Shao-Yi,Chao, Shih-Chi,Chiu, Sheng-Po,Lee, Shiao-Pieng,Lo, Chun-Min  (2020).  Sensors  20 (9) :  2632 doi:https://doi.org/10.3390/s20092632 [Abstract]

Phenotypic and functional characterization of corneal endothelial cells during in vitro expansion.,  Frausto, Ricardo F,Swamy, Vinay S,Peh, Gary S L,Boere, Payton M,Hanser, E Maryam,Chung, Doug D,George, Benjamin L,Morselli, Marco,Kao, Liyo,Azimov, Rustam,Wu, Jessica,Pellegrini, Matteo,Kurtz, Ira,Mehta, Jodhbir S,Aldave, Anthony J  (2020).  Scientific Reports  10 (7402) :  1-22 doi:10.1038/s41598-020-64311-x [Abstract]

Sigma-1 Receptor Activation-Induced Glycolytic ATP Production and Endothelial Barrier Enhancement..,  Motawe, ZY,Farsaei, F,Abdelmaboud, SS,Cuevas, J,Breslin, JW  (2020).  Microcirculation  [Abstract]

Inflammatory Conditions Disrupt Constitutive Endothelial Cell Barrier Stabilization by Alleviating Autonomous Secretion of Sphingosine 1-Phosphate.,  Paul, Jefri Jeya,Weigel, Cynthia,Müller, Tina,Heller, Regine,Spiegel, Sarah,Gräler, Markus H  (2020).  Cells  9 (4) :  928 [Abstract]

Arg mediates LPS-induced disruption of the pulmonary endothelial barrier.,  Rizzo, Alicia N.,Belvitch, Patrick,Demeritte, Regaina,Garcia, Joe G.N.,Letsiou, Eleftheria,Dudek, Steven M.  (2020).  Vascular Pharmacology  (October 2019) :  106677 doi:10.1016/j.vph.2020.106677 [Abstract]

Extracorporeal cytokine removal in severe CAR-T cell associated cytokine release syndrome.,  Stahl, Klaus,Schmidt, Bernhard M.W.,Hoeper, Marius M.,Skripuletz, Thomas,Möhn, Nora,Beutel, Gernot,Eder, Matthias,Welte, Tobias,Ganser, Arnold,Falk, Christine S.,Koenecke, Christian,David, Sascha  (2020).  Journal of Critical Care  57 124-129 doi:10.1016/j.jcrc.2020.02.010 [Abstract]

Placental growth factor regulates the pentose phosphate pathway and antioxidant defense systems in human retinal endothelial cells.,  Saddala, Madhu Sudhana,Lennikov, Anton,Huang, Hu  (2020).  Journal of Proteomics  217 (December 2019) :  103682 doi:10.1016/j.jprot.2020.103682 [Abstract]

Application of Impedance-Based Techniques in Hepatology Research.,  Morgan, Katie,Gamal, Wesam,Samuel, Kay,Morley, Steven D,Hayes, Peter C,Bagnaninchi, Pierre,Plevris, John N  (2020).  Journal of Clinical Medicine  9 (50) :  [Abstract]