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ECIS® CP96


Cell Population Monitor

Description


Cell population is measured in real time, under incubator conditions, label-free and in 96 wells. Introducing the all new CP96 by Applied Biophysics, Inc. Data collection made easy.”

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Overview


The CP96 Cell Population Monitor is based upon the ECIS (Electric Cell-Substrate Impedance Sensing) technology where cells are grown upon gold electrodes carrying very weak AC signals. This complete turn-key system provides a means to carry out reproducible, label-free, automated cell population measurements without damaging the cells. Cell population is monitored as cells are grown in a normal CO2 tissue culture incubator, and data are reported as real-time changes in percent of cell-substrate coverage.

Benefits
  • - Automated cell population monitoring in 96 wells
  • - Data recorded and visualized in real time under incubator conditions
  • - Long-term data collection capabilities
  • - Non-invasive & label free
  • - Highly reproducible
  • - User Friendly software
  • - Calculate EC50 values
  • - Data output in CSV or graphical (jpg, tif)
  • - Impedance data converted to percent of cell-substrate coverage
  • - Create figures and plots of data
CP96 Graph
Features
  • - Follow dynamics of cell-substrate coverage
  • - Study cytotoxic effects of compounds upon cell proliferation or loss of viability
  • - Calculate EC50 values
System Includes:
  • - 96 channel station
  • - External control module
  • - Laptop PC
  • - ECIS control, acquisition, and display software
  • - Validation test array
  • - Six 96W20idf consumable electrode arrays
CP96 Includes

These non-invasive measurements can be made for days and even weeks without the need to remove the station from the incubator, eliminating unwanted temperature and pH variations.

Compounds affecting cell behavior can be introduced before or after the cells have covered the substrate to distinguish changes in growth from the cells to detaching from the substrate. And with the capability of measuring 96 wells continuously, the CP96 allows for a high throughput of data to be collected and analyzed in real time, making cell population monitoring simple and efficient.

  • - 96 well plates are barcoded with serial numbers for tracking
  • - Gold electrodes
  • - 48 KHz sinusoidal signal
  • - Power: < 1 watt, 12 V dc
  • - Station: 25.5 x 18 x 4.5 cm, 2.3 kg
  • - Controller: 30.2 x 22.2 x 9.8 cm, 2.3 kg
  • - Connects to laptop via USB
  • - Windows 10

Data Sheets