ECIS is used in over 160 labs worldwide and ECIS data has been published in a growing list of over 400 peer-reviewed publications.

ECIS electrically monitors cell morphological changes and provides quantitative, real-time measurements of cell motility, attachment and spreading, and barrier function. Experimental protocols include studies of cell-integrin interactions, metastatic invasion, signal transduction, and cell migration (via automated wound/healing).

The ECIS Application Webinar series will review the topics listed below in 20 minute, web-based, interactive seminars. To view a pre-recorded video of the Introduction to ECIS click here: ECIS Introduction (11:02)

All Webinars are presented by Dr. Charles Keese, President Applied BioPhysics.

2012 WEBINAR SCHEDULE

ECIS Theory – 11:00 AM EST
January 10, 2012
This webinar will provide an overview of the use of impedance (both simple and complex) to detect cell morphological changes. Emphasis will be placed on the use of different AC frequencies to distinguish cell parameters. To view a pre-recorded video of this webinar click here: ECIS Theory(22:55)

Cell Invasion / Extravasation Assays – 11:00 AM EST
January 24, 2012
This webinar will review ECIS as it is used to monitor endothelial monolayers as they are challenged with metastatic cell lines. Extravasation of these layers can be followed in real time to provide quantitative data regarding the metastatic potential of the cancer cells. To view a pre-recorded video of this webinar click here: Cell Invasion Assays (9:19)

Automated Cell Migration – 11:00 AM EST
February 7, 2012
The ECIS Wound Healing Assay replaces the traditional "scratch" or "scrape" assay. Instead of disrupting the cell layer mechanically with a needle or pipette tip and following the migration of cells to "heal" the wound with a microscope, we employ electric signals to both wound and monitor the healing process. We will also describe a novel and new approach to this measurement called the “electric fence”.  This webinar will review the basic principles of ECIS and then present quantitative data regarding these automated assays. To view a pre-recorded video of this webinar click here: Cell Migration (10:27)
 
Barrier Function Assays – 11:00 AM EST
February 21, 2012
This webinar will review ECIS and then show how complex impedance measurements can be used to evaluate the barrier function (permeability) of confluent endothelial monolayers. The ability of ECIS data to be mathematically modeled will be briefly introduced.

Real-time Electroporation and Monitoring – 11:00 AM EST
March 6, 2012
ECIS can be used to electroporate cells and then to immediately follow the results of the electroporation in real-time. This unique feature of the ECIS technology will be described in this webinar and sample data presented. To view a pre-recorded video of this webinar click here: Electroporation (10:28)

Cell Attachment and Spreading Measurements – 11:00 AM EST
March 20, 2012
The webinar will review ECIS and then present quantitative data gathered in real time regarding the attachment and spreading behavior of cells upon extracellular matrix proteins. 

Signal Transduction Assays – 11:00 AM EST
April 3, 2012
Data will be presented showing the ability of ECIS to monitor signal transduction in label-free, whole-cell assays. The morphological changes responsible for the impedance changes will be further evaluated by modeling the complex impedance data. To view a pre-recorded video of this webinar click here: Signal Transduction Assays (7:16)

Toxicology with ECIS – 11:00 AM EST
April 17, 2012
This webinar will review ECIS and then present data showing how ECIS impedance measurements respond to varying concentrations of toxic compounds.

ECIS Theory – 11:00 AM EST
May 8, 2012
This webinar will provide an overview of the use of impedance (both simple and complex) to detect cell morphological changes. Emphasis will be placed on the use of different AC frequencies to distinguish cell parameters. To view a pre-recorded video of this webinar click here: ECIS Theory(22:55)

Cell Invasion / Extravasation Assays – 11:00 AM EST
May 22, 2012
This webinar will review ECIS as it is used to monitor endothelial monolayers as they are challenged with metastatic cell lines. Extravasation of these layers can be followed in real time to provide quantitative data regarding the metastatic potential of the cancer cells. To view a pre-recorded video of this webinar click here: Cell Invasion Assays (9:19)

Automated Cell Migration – 11:00 AM EST
June 5, 2012
The ECIS Wound Healing Assay replaces the traditional "scratch" or "scrape" assay. Instead of disrupting the cell layer mechanically with a needle or pipette tip and following the migration of cells to "heal" the wound with a microscope, we employ electric signals to both wound and monitor the healing process. We will also describe a novel and new approach to this measurement called the “electric fence”.  This webinar will review the basic principles of ECIS and then present quantitative data regarding these automated assays. To view a pre-recorded video of this webinar click here: Cell Migration (10:27)

Barrier Function Assays – 11:00 AM EST
June 19, 2012
This webinar will review ECIS and then show how complex impedance measurements can be used to evaluate the barrier function (permeability) of confluent endothelial monolayers. The ability of ECIS data to be mathematically modeled will be briefly introduced.

Real-time Electroporation and Monitoring – 11:00 AM EST
July 10, 2012
ECIS can be used to electroporate cells and then to immediately follow the results of the electroporation in real-time. This unique feature of the ECIS technology will be described in this webinar and sample data presented. To view a pre-recorded video of this webinar click here: Electroporation (10:28)

Cell Attachment and Spreading Measurements – 11:00 AM EST
July 24, 2012
The webinar will review ECIS and then present quantitative data gathered in real time regarding the attachment and spreading behavior of cells upon extracellular matrix proteins. 

Signal Transduction Assays – 11:00 AM EST
September 14, 2012
Data will be presented showing the ability of ECIS to monitor signal transduction in label-free, whole-cell assays. The morphological changes responsible for the impedance changes will be further evaluated by modeling the complex impedance data. To view a pre-recorded video of this webinar click here: Signal Transduction Assays (7:16)

Toxicology with ECIS – 11:00 AM EST
September 18, 2012
This webinar will review ECIS and then present data showing how ECIS impedance measurements respond to varying concentrations of toxic compounds.

ECIS Theory – 11:00 AM EST
October 9, 2012
This webinar will provide an overview of the use of impedance (both simple and complex) to detect cell morphological changes. Emphasis will be placed on the use of different AC frequencies to distinguish cell parameters. To view a pre-recorded video of this webinar click here: ECIS Theory(22:55)

Cell Invasion / Extravasation Assays – 11:00 AM EST
October 23, 2012
This webinar will review ECIS as it is used to monitor endothelial monolayers as they are challenged with metastatic cell lines. Extravasation of these layers can be followed in real time to provide quantitative data regarding the metastatic potential of the cancer cells. To view a pre-recorded video of this webinar click here: Cell Invasion Assays (9:19)

Automated Cell Migration – 11:00 AM EST
November 13, 2012
The ECIS Wound Healing Assay replaces the traditional "scratch" or "scrape" assay. Instead of disrupting the cell layer mechanically with a needle or pipette tip and following the migration of cells to "heal" the wound with a microscope, we employ electric signals to both wound and monitor the healing process. We will also describe a novel and new approach to this measurement called the “electric fence”.  This webinar will review the basic principles of ECIS and then present quantitative data regarding these automated assays. To view a pre-recorded video of this webinar click here: Cell Migration (10:27)

Barrier Function Assays – 11:00 AM EST
November 27, 2012
This webinar will review ECIS and then show how complex impedance measurements can be used to evaluate the barrier function (permeability) of confluent endothelial monolayers. The ability of ECIS data to be mathematically modeled will be briefly introduced.

Real-time Electroporation and Monitoring – 11:00 AM EST
December 11, 2012
ECIS can be used to electroporate cells and then to immediately follow the results of the electroporation in real-time. This unique feature of the ECIS technology will be described in this webinar and sample data presented. To view a pre-recorded video of this webinar click here: Electroporation (10:28)