The ECIS™800 is a limited application research instrument having the capacity to monitor up to 16 individual tissue culture wells (one 8 well arrays). The impedance of small active electrodes in each well is measured in real time to record cell activity and response to agents. This instrument monitors the simple (rather than complex) impedance at one fixed frequency covering the range where impedance changes due to the presence of the cells are strongest. In addition to monitoring the cells non-invasively, this instrument can be equipped with the Elevated Field Module option allowing the performance of automated wound-healing (cell migration) assays [PNAS 101: 1554-1559 (2004)] and experiments involving electroporation of membrane-impermeable compounds.
The electronics are consolidated in a single case that sits beside a tissue culture incubator. Two leads connect the electronics to an ECIS electrode array holder within the incubator space – this, in turn, makes contact with up to two consumable ECIS arrays. A USB cable provides communication to a PC that controls all data acquisition, storage and analysis. In addition to the ECIS electronics and software, the system is supplied with a state-of-the-art laptop, and an initial supply of ECIS electrode arrays.
The user-friendly ECIS software runs on a Window's XP Profession platform for all operations. In addition to using the ECIS analysis and plotting programs, one can readily convert data to text files for export to other data analysis systems.
An optional compact CO2 tissue culture incubator is also available.
See also our instrument comparison chart.
For More Information Please Contact BTX