CHARLES R. KEESE
Applied
BioPhysics, Inc. and Rensselaer Polytechnic Institute
Troy, NY 12180 USA
Dr. Keese is Vice President of Applied BioPhysics, Inc. and a Senior Research Scientist in
the Department of Biology at Rensselaer Polytechnic Institute. His work is largely
involved in research and development of a laboratory instrument for biology and medicine
referred to as ECIS for electric cell substrate
impedance sensing. This approach monitors the actitivies of cells as they are grown on
small gold electrodes at the base of tissue culture wells. Much support for this endeavor
has come from SBIR
grants from the National Institutes of Health including the National Center for
Research Resources, the National Cancer Institute and the National Institute for
Environmental Health Science. ECIS can follow a variety of cell behaviors including
attachment and spreading, cell growth, and cellular motions.
Past experience includes: Research Scientist at General Electric
Corporate Research and Development, Codirector of the Regional Laboratory of the National Foundation for Cancer
Research at GE CRD; Professor of Biology at SUNY
at Cobleskill.
Research interests include: impedance measurements of cells in culture; behavior of macromolecules and cells
at interfaces; growth of cells on fluorocarbon oil interfaces; development of new
immunodiagnostic methods.
Dr. Keese works closely with Dr. Ivar Giaever (Nobel Prize in Physics 1973) in research
and development of new biophysical methods to study cells and molecules at surfaces.
If you have comments or suggestions, email me at keesec@rpi.edu or keese@biophysics.com